Construction and characterisation of a modular microfluidic system: Coupling magnetic capture and electrochemical detection

Microfluidics and Nanofluidics

Volumn 8, Issue 3, 2010, Pages 393-402

  Godino, Neus ^a   Snakenborg, Detlef ^b   Kutter, Jörg P ^b   Emnéus, Jenny ^b   Hansen, Mikkel Fougt ^b   Muñoz, F Xavier ^a   Javier Del Campo, F ^a  

^a INSTITUTO DE MICROELECTRÓNICA DE BARCELONA   (Spain)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Aminophenol; Channel electrode; Electrochemistry; Galactosidase; Lab on a chip; Microfluidics; PDMS

Indexed keywords

AMINOPHENOL; CHANNEL ELECTRODES; GALACTOSIDASE; GALACTOSIDASES; LAB-ON-A-CHIP;

CHEMICAL DETECTION; DETECTORS; ELECTROCHEMISTRY; ENZYME ACTIVITY; ENZYMES; FLUIDIC DEVICES; MAGNETS; MICROCHANNELS; SILICONES;

MICROFLUIDICS;

EID: 77649237095     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-009-0468-8     Document Type: Article

References (38)

1. JA Alden MA Feldman E Hill F Prieto M Oyama BA Coles RG Compton PJ Dobson PA Leigh 1998 Channel microband electrode arrays for mechanistic electrochemistry. Two-dimensional voltammetry: transport-limited currents Anal Chem 70 1707 1720 10.1021/ac971248i
2. C Amatore N Da Mota C Sella L Thouin 2008 General concept of high-performance amperometric detector for microfluidic (bio)analytical chips Anal Chem 80 4976 4985 10.1021/ac800227t (Pubitemid 351956305)
3. E Baldrich FX Muñoz 2008 Enzyme shadowing: using antibody-enzyme dually labeled magnetic particles for fast bacterial detection Analyst 133 1009 1012 10.1039/b805536j (Pubitemid 352033098)
4. Bard AJ, Faulkner LR (2001) Electrochemical methods: fundamentals and applications. Wiley, Chichester
5. JW Choi KW Oh JH Thomas WR Heineman HB Halsall JH Nevin AJ Helmicki HT Henderson CH Ahn 2002 An integrated microfluidic biochemical detection system for protein analysis with magnetic bead-based sampling capabilities Lab Chip 2 27 30 10.1039/b107540n (Pubitemid 37248115)
6. Compton RG, Banks CE (2007) Understanding voltammetry. World Scientific Publishing, Singapore
7. RG Compton AC Fisher RG Wellington PJ Dobson PA Leigh 1993 Hydrodynamic voltammetry with microelectrodes. Channel microband electrodes: theory and experiment J Phys Chem 97 10410 10415 10.1021/j100142a024
8. JB Conant MF Pratt 1926 The irreversible oxidation of organic compounds I. The oxidation of aminophenols by reagents of definite potential JACS 48 3178 3192 10.1021/ja01691a026
9. JA Cooper RG Compton 1998 Channel electrodes-a review Electroanalysis 10 141 155 10.1002/(SICI)1521-4109(199803)10:3<141::AID-ELAN141>3.0.CO;2-F
10. J Do CH Ahn 2008 A polymer lab-on-a-chip for magnetic immunoassay with on-chip sampling and detection capabilities Lab Chip 8 542 549 10.1039/b715569g
11. DC Duffy JC Mcdonald OJA Schueller GM Whitesides 1998 Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) Anal Chem 70 4974 4984 10.1021/ac980656z (Pubitemid 28553167)
12. S Farrell NJ Ronkainen-Matsuno HB Halsall WR Heineman 2004 Bead-based immunoassays with microelectrode detection Anal Bioanal Chem 379 358 367 10.1007/s00216-004-2632-z (Pubitemid 40877560)
13. PS Francis SW Lewis KF Lim K Carlsson B Karlberg 2002 Flow analysis based on a pulsed flow of the solution: theory, instrumentation and applications Talanta 58 1029 1042 10.1016/S0039-9140(02)00426-5
14. M Gabig-Ciminska A Holmgren H Andresen K Bundvig Barken M Wümpelmann J Albers R Hintsche A Breitenstein P Neubauer M Los A Czyz G Wegrzyn G Silfversparre B Jürgen T Schweder SO Enfors 2004 Electric chips for rapid detection and quantification of nucleic acids Biosens Bioelectron 19 537 546 10.1016/S0956-5663(03)00273-2 (Pubitemid 37547944)
15. MAM Gijs 2004 Magnetic bead handling on-chip: new opportunities for analytical applications Microfluid Nanofluid 1 22 40
16. D Goncalves RC Faria M Yonashiro LOS Bulhoes 2000 Electrochemical oxidation of o-aminophenol in aqueous acidic medium: formation of film and soluble products J Electroanal Chem 487 90 99 10.1016/S0022-0728(00)00151-0 (Pubitemid 30942148)
17. VN Goral NV Zaytseva AJ Baeumner 2006 Electrochemical microfluidic biosensor for the detection of nucleic acid sequences Lab Chip 6 414 421 10.1039/b513239h (Pubitemid 43327567)
18. X Llopis M Pumera S Alegret A Merkoçi 2009 Lab-on-a-chip for ultrasensitive detection of carbofuran by enzymatic inhibition with replacement of enzyme using magnetic beads Lab Chip 9 213 218 10.1039/b816643a
19. T Lund-Olesen H Bruus MF Hansen 2007 Quantitative characterization of magnetic separators: comparison of systems with and without integrated microfluidic mixers Biomed Microdev 9 195 205 10.1007/s10544-006-9021-7 (Pubitemid 46554127)
20. M Másson Z Liu T Haruyama E Kobatake Y Ikariyama M Aizawa 1995 Immunosensing with amperometric detection, using galactosidase as label and p-aminophenyl-B-d-galactopyranoside as substrate Anal Chim Acta 304 353 359 10.1016/0003-2670(94)00645-3
21. JC Mcdonald GM Whitesides 2002 Poly(dimethylsiloxane) as a material for fabricating microfluidic devices Acc Chem Res 35 491 499 10.1021/ar010110q
22. C Mikkelsen M Fougt Hansen H Bruus 2005 Theoretical comparison of magnetic and hydrodynamic interactions between magnetically tagged particles in microfluidic systems J Magn Magn Mater 293 578 583 10.1016/j.jmmm.2005.01.076 (Pubitemid 40608983)
23. PD Morland RG Compton 1999 Heterogeneous and homogeneous EC and ECE processes at channel electrodes: analytical wave shape theory J Phys Chem B 103 8951 8959 10.1021/jp991922v
24. RS Nicholson I Shain 1964 Theory of stationary electrode polarography single scan and cyclic methods applied to reversible, irreversible, and kinetic systems Anal Chem 36 706 723 10.1021/ac60210a007
25. O Niwa Y Xu H Brian Halsall WR Heineman 1993 Small-volume voltammetric detection of 4-aminophenol with interdigitated array electrodes and its application to electrochemical enzyme immunoassay Anal. Chem. 65 1559 1563 10.1021/ac00059a013
26. V Plichon G Faure 1973 Thin-layer electrochemistry-applications to chemical-kinetics-example of para-aminophenol J Electroanal Chem 44 275 290 10.1016/S0022-0728(73)80253-0
27. NV Rees RG Compton 2008 Hydrodynamic microelectrode voltammetry Russ J Electrochem 44 368 389 10.1134/S1023193508040034 (Pubitemid 351725899)
28. JS Rossier HH Girault 2001 Enzyme-linked immunosorbent assay on a microchip with electrochemical detection Lab Chip 1 153 157 10.1039/b104772h
29. H Shinohara J Mizuno S Shoji 2007 Low-temperature direct bonding of poly(methyl methacrylate) for polymer microchips IEE J Trans Elect Electron Eng 2 301 306 10.1002/tee.20157 (Pubitemid 46715016)
30. K Smistrup M Bu A Wolff H Bruus MF Hansen 2008 Theoretical analysis of a new, efficient microfluidic magnetic bead separator based on magnetic structures on multiple length scales Microfluid. Nanofluid. 4 565 573 10.1007/s10404-007- 0213-0 (Pubitemid 351722205)
31. D Snakenborg G Perozziello H Klank O Geschke JP Kutter 2006 Direct milling and casting of polymer-based optical waveguides for improved transparency in the visible range J Micromech Microeng 16 375 381 10.1088/0960-1317/16/2/023 (Pubitemid 43146242)
32. JH Thomas SK Kim PJ Hesketh HB Halsall WR Heineman 2004 Microbead-based electrochemical immunoassay with interdigitated array electrodes Anal Biochem 328 113 122 10.1016/j.ab.2004.02.020 (Pubitemid 38542926)
33. K Tokuda H Matsuda 1974 Theory of stationary current-voltage curves of redox-electrode reactions in hydrodynamic voltammetry. IX. Double electrodes in channel flow J Electroanal Chem 52 421 431 10.1016/S0022-0728(74)80452-3
34. CW Tsao L Hromada J Liu P Kumar DL Devoe 2007 Low temperature bonding of PMMA and COC microfluidic substrates using UV/ozone surface treatment Lab Chip 7 499 505 10.1039/b618901f (Pubitemid 46496556)
35. E Verpoorte 2003 Beads and chips: new recipes for analysis Lab Chip 3 60N 10.1039/b313217j
36. Voet D, Voet JG (1995) Biochemistry. John Wiley & Sons, New York
37. CR Wilke P Chang 1955 A I Ch E J 1 264
38. S Yamaguchi S Mitsugi 1997 Sensitive amperometry of 4-aminophenol (4AP) based on the catalytic current produced by the 4AP-diphorase-NADH system at a glassy carbon electrode and its application to enzyme assay. Effect of the inhibition of diaphorase by NADH Anal Sci 13 307 309 10.2116/analsci.13.307