Maxillary sinus floor elevation using a tissue engineered bone complex with BMP-2 gene modified bMSCs and a novel porous ceramic scaffold in rabbits

Archives of Oral Biology

Volumn 55, Issue 3, 2010, Pages 195-202

  Sun, X Juan ^a,b   Xia, L Guo ^a   Chou, L Lee ^c   Zhong, Wei ^d   Zhang, X Li ^a   Wang, S Yi ^a   Zhao, Jun ^a   Jiang, X Quan ^a   Zhang, Z Yuan ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c BOSTON UNIVERSITY   (United States)

^d Chinese Academy of Sciences   (China)

Author keywords

Bone marrow stromal cells; Bone morphogenetic protein; Gene therapy; Sinus floor elevation; Tissue engineering scaffold

Indexed keywords

BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; DIAGNOSTIC AGENT; GREEN FLUORESCENT PROTEIN; LUMINESCENT AGENT; TISSUE SCAFFOLD;

ADENOVIRUS; ANIMAL; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; CELL ADHESION; CELL MOTION; CERAMICS; CHEMISTRY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CYTOLOGY; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; IMAGE PROCESSING; MALE; MAXILLA; MAXILLARY SINUS; METHODOLOGY; ORAL SURGERY; OSTEOTOMY; PATHOLOGY; PHYSIOLOGY; RABBIT; RANDOMIZATION; STROMA CELL; TISSUE ENGINEERING;

ADENOVIRIDAE; ALVEOLAR RIDGE AUGMENTATION; ANIMALS; BIOCOMPATIBLE MATERIALS; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; CELL ADHESION; CELL MOVEMENT; CERAMICS; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; LUMINESCENT AGENTS; MALE; MAXILLA; MAXILLARY SINUS; MICROSCOPY, CONFOCAL; MODELS, ANIMAL; OSTEOGENESIS; OSTEOTOMY; RABBITS; RANDOM ALLOCATION; STROMAL CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSDUCTION, GENETIC;

ADENOVIRIDAE; ORYCTOLAGUS CUNICULUS;

EID: 77649232756     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2010.01.006     Document Type: Article

References (23)

1. Schimming R., and Schmelzeisen R. Tissue-engineered bone for maxillary sinus augmentation. J Oral Maxillofac Surg 62 6 (2004) 724-729
2. Sun X.J., Zhang Z.Y., Wang S.Y., Gittens S.A., Jiang X.Q., and Chou L.L. Maxillary sinus floor elevation using tissue-engineered bone complex with OsteoBone™ and bMSCs in rabbits. Clin Oral Implants Res 19 8 (2008) 804-813
3. Schek R.M., Wilke E.N., Hollister S.J., and Krebsbach P.H. Combined use of designed scaffolds and adenoviral gene therapy for skeletal tissue engineering. Biomaterials 27 7 (2006) 1160-1166
4. Lieberman J.R., Le L.Q., Wu L., Finerman G.A., Berk A., Witte O.N., et al. Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents. J Orthop Res 16 3 (1998) 330-339
5. Musgrave D.S., Bosch P., Ghivizzani S., Robbins P.D., Evans C.H., and Huard J. Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone. Bone 24 6 (1999) 541-547
6. Jiang X.Q., Chen J.G., Gittens S., Chen C.J., Zhang X.L., and Zhang Z.Y. The ectopic study of tissue-engineered bone with hBMP-4 gene modified bone marrow stromal cells in rabbits. Chin Med J (Engl) 118 4 (2005) 281-288
7. Aghaloo T., Jiang X., Soo C., Zhang Z., Zhang X., Hu J., et al. A study of the role of Nell-1 gene modified goat bone morrow stromal cells in promoting new bone formation. Mol Ther 15 10 (2007) 1872-1880
8. Jiang X., Gittens S.A., Chang Q., Zhang X., Chen C., and Zhang Z. The use of tissue-engineered bone with human bone morphogenetic protein-4-modified bone-marrow stromal cells in repairing mandibular defects in rabbit. Int J Oral Maxillofac Surg 35 12 (2006) 1133-1139
9. Asai S., Shimizu Y., and Ooya K. Maxillary sinus augmentation model in rabbits: effect of occluded nasal ostium on new bone formation. Clin Oral Implants Res 13 4 (2002) 405-409
10. Xu H., Shimizu Y., Asai S., and Ooya K. Experimental sinus grafting with the use of deproteinized bone particles of different sizes. Clin Oral Implants Res 14 5 (2003) 548-555
11. Donath K., and Breuner G. A method for the study of undecalcified bones and teeth with attached soft tissues. The Sage-Schliff (sawing and grinding) technique. J Oral Pathol 11 4 (1982) 318-326
12. Rohrer M.D., and Schubert C.C. The cutting-grinding technique for histologic preparation of undecalcified bone and bone-anchored implants. Improvements in instrumentation and procedures. Oral Surg Oral Med Oral Pathol 74 1 (1992) 73-78
13. Stocks S.M. Mechanism and use of the commercially available viability stain. Cytometry A 61 2 (2004) 189-195
14. Turgemann G., Zilberman Y., Zhou S., Kelly P., Moutsatsos I.K., Kharode Y.P., et al. Systemically administered rhBMP-2 promotes MSC activity and reverses bone and cartilage loss in osteopenic mice. J Cell Biochem 86 3 (2002) 461-474
15. Stagg J., Lejeune L., Paquin A., and Galipeau J. Marrow stromal cells for interleukin-2 delivery in cancer immunotherapy. Hum Gene Ther 15 6 (2004) 597-608
16. Reiser J., Zhang X.Y., Hemenway C.S., Mondal D., Pradhan L., and Russa L. Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases. Expert Opin Biol Ther 5 12 (2005) 1571-1584
17. Gazit D., Turgeman G., Kelley P., Wang E., Jalenak M., and Zilberman Y. Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy. J Gene Med 1 2 (1999) 121-133
18. Gosain A.K. Bioactive glass for bone replacement in craniomaxillofacial reconstruction. Plast Reconstr Surg 114 2 (2004) 590-593
19. Tadjoedin E.S., de Lange G.L., Holzmann P.J., Kulper L., and Burger E.H. Histological observations on biopsies harvested following sinus floor elevation using a bioactive glass material of narrow size range. Clin Oral Implants Res 11 4 (2000) 334-344
20. Al Ruhaimi K.A. Bone graft substitutes: a comparative qualitative histologic review of current osteoconductive grafting materials. Int J Oral Maxillofac Implants 16 1 (2001) 105-114
21. Smiler D.G., Johnson P.W., Lozada J.L., Misch C., Rosenlicht J.L., Tatum Jr. O.H., et al. Sinus lift grafts and endosseous implants. Treatment of the atrophic posterior maxilla. Dent Clin North Am 36 1 (1992) 151-186 [Discussion 187-8]
22. Schlegel K.A., Fichtner G., Schultze-Mosgau S., and Wiltfang J. Histologic findings in sinus augmentation with autogenous bone chips vs. a bovine bone substitute. Int J Oral Maxillofac Implants 18 1 (2003) 53-58
23. Chang S.C., Chung H., and Chen Y.R. Cranial repair using BMP-2 gene engineered bone marrow stromal cells. J Surg Res 119 1 (2004) 85-91