Murine model of Hirschsprung-associated enterocolitis. I: Phenotypic characterization with development of a histopathologic grading system

Journal of Pediatric Surgery

Volumn 45, Issue 3, 2010, Pages 475-482

  Cheng, Zhi ^a   Dhall, Deepti ^b   Zhao, Lifu ^a   Wang, Hanlin L ^b   Doherty, Terence M ^b   Bresee, Catherine ^b   Frykman, Philip K ^a  

^a Division of Pediatric Surgery   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Aganglionic megacolon; Ednrb B null mice; Enteric nervous system; Enteric neuropathy; Hirschsprung's disease; Hirschsprung associated enterocolitis; Histopathologic grading system

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; ASCENDING COLON; BACTEREMIA; BACTERIUM CULTURE; COLONY FORMING UNIT; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIET RESTRICTION; DISEASE SEVERITY; ENTEROCOLITIS; FEMALE; HIRSCHSPRUNG DISEASE; HISTOPATHOLOGY; ILEUM; INFLAMMATION; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; PERITONEUM LAVAGE; PHENOTYPE; PRIORITY JOURNAL; SCORING SYSTEM; SMALL INTESTINE; SPLEEN; STAINING; SURVIVAL TIME; TISSUE HOMOGENATE;

ANIMALS; BACTEREMIA; BIOPSY, NEEDLE; DISEASE MODELS, ANIMAL; ENTERIC NERVOUS SYSTEM; ENTEROCOLITIS; GASTROINTESTINAL TRANSIT; HIRSCHSPRUNG DISEASE; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; PHENOTYPE; PROBABILITY; RANDOM ALLOCATION; RECEPTOR, ENDOTHELIN B; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC;

EID: 77649194185     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2009.06.009     Document Type: Article

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