Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Biochemical Pharmacology

Volumn 79, Issue 9, 2010, Pages 1310-1316

  Cronican, Andrea A ^a   Fitz, Nicholas F ^a   Pham, Tam ^a   Fogg, Allison ^a   Kifer, Brionna ^a   Koldamova, Radosveta ^a   Lefterov, Iliya ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

ABCA1; APOE; Gene expression; Liver X receptors; LXR knockout mice; Primary astrocytes; Proton pump inhibitors

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN E; ESOMEPRAZOLE; LANSOPRAZOLE; LIVER X RECEPTOR AGONIST; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MESSENGER RNA; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR;

ANIMAL CELL; ARTICLE; ASSAY; ASTROCYTE; CELL LEVEL; CONTROLLED STUDY; DRUG SCREENING; GENE EXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANIMALS; APOLIPOPROTEINS E; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, KNOCKOUT; MOLECULAR STRUCTURE; NEUROGLIA; OMEPRAZOLE; ORPHAN NUCLEAR RECEPTORS; PROTON PUMP INHIBITORS;

EID: 77649188082     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.12.018     Document Type: Article

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