Co-expression of Japanese encephalitis virus prM-E-NS1 antigen with granulocyte-macrophage colony-stimulating factor enhances humoral and anti-virus immunity after DNA vaccination

Immunology Letters

Volumn 129, Issue 1, 2010, Pages 23-31

  Gao, Na ^a   Chen, Wei ^a   Zheng, Qun ^b   Fan, Dong ying ^b   Zhang, Jun lei ^a   Chen, Hui ^b   Gao, George F ^c   Zhou, De shan ^b   An, Jing ^b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Adjuvant; DNA vaccine; Granulocyte macrophage colony stimulating factor; Japanese encephalitis virus

Indexed keywords

DNA VACCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN G; JAPANESE ENCEPHALITIS VACCINE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; DRUG EFFICACY; EPIDEMIC ENCEPHALITIS; FEMALE; HUMORAL IMMUNITY; IMMUNIZATION; INFECTION PREVENTION; JAPANESE ENCEPHALITIS VIRUS; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; SURVIVAL RATE; VIRUS IMMUNITY;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, VIRAL; CELL LINE; CLONING, MOLECULAR; CYTOTOXICITY, IMMUNOLOGIC; ENCEPHALITIS VIRUS, JAPANESE; ENCEPHALITIS, JAPANESE; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNITY, HUMORAL; MICE; MICE, INBRED BALB C; VACCINES, DNA; VIRAL NONSTRUCTURAL PROTEINS;

EID: 77649183747     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.12.023     Document Type: Article

References (37)

1. van den Hurk A.F., Ritchie S.A., and Mackenzie J.S. Ecology and geographical expansion of Japanese encephalitis virus. Annual Review of Entomology 54 (2009) 17-35
2. Parida M., Dash P.K., Tripathi N.K., Ambuj, Sannarangaiah S., Saxena P., et al. Japanese Encephalitis Outbreak, India, 2005. Emerging Infectious Diseases 12 (2006) 1427-1430
3. Bray M., and Lai C.J. Dengue virus premembrane and membrane proteins elicit a protective immune response. Virology 185 (1991) 505-508
4. Konishi E., and Mason P.W. Proper maturation of the Japanese encephalitis virus envelope glycoprotein requires cosynthesis with the premembrane protein. Journal of Virology 67 (1993) 1672-1675
5. Schlesinger J.J., Foltzer M., and Chapman S. The Fc portion of antibody to yellow fever virus NS1 is a determinant of protection against YF encephalitis in mice. Virology 192 (1993) 132-141
6. Chen H.W., Pan C.H., Liau M.Y., Jou R., Tsai C.J., Wu H.J., et al. Screening of protective antigens of Japanese encephalitis virus by DNA immunization: a comparative study with conventional viral vaccines. Journal of Virology 73 (1999) 10137-10145
7. Pan C.H., Chen H.W., Huang H.W., and Tao M.H. Protective mechanisms induced by a Japanese encephalitis virus DNA vaccine: requirement for antibody but not CD8(+) cytotoxic T-cell responses. Journal of Virology 75 (2001) 11457-11463
8. Kaur R., Sachdeva G., and Vrati S. Plasmid DNA immunization against Japanese encephalitis virus: immunogenicity of membrane-anchored and secretory envelope protein. The Journal of Infectious Diseases 185 (2002) 1-12
9. Zhao Z., Wakita T., and Yasui K. Inoculation of plasmids encoding Japanese encephalitis virus PrM-E proteins with colloidal gold elicits a protective immune response in BALB/c mice. Journal of Virology 77 (2003) 4248-4260
10. Konishi E., Ajiro N., Nukuzuma C., Mason P.W., and Kurane I. Comparison of protective efficacies of plasmid DNAs encoding Japanese encephalitis virus proteins that induce neutralizing antibody or cytotoxic T lymphocytes in mice. Vaccine 21 (2003) 3675-3683
11. Wu Y., Zhang F., Ma W., Song J., Huang Q., and Zhang H. A plasmid encoding Japanese encephalitis virus PrM and E proteins elicits protective immunity in suckling mice. Microbiology and Immunology 48 (2004) 585-590
12. Wu C.J., Li T.L., Huang H.W., Tao M.H., and Chan Y.L. Development of an effective Japanese encephalitis virus-specific DNA vaccine. Microbes and Infection/Institut Pasteur 8 (2006) 2578-2586
13. Lin Y.L., Chen L.K., Liao C.L., Yeh C.T., Ma S.H., Chen J.L., et al. DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice. Journal of Virology 72 (1998) 191-200
14. Chen W., Lin Y., Liao C., and Hsieh S. Modulatory effects of the human heat shock protein 70 on DNA vaccination. Journal of Biomedical Science 7 (2000) 412-419
15. Mellado-Sanchez G., Garcia-Cordero J., Luria-Perez R., Lazaro-Olan L., Santos-Argumedo L., Gutierrez-Castaneda B., et al. DNA priming E and NS1 constructs-homologous proteins boosting immunization strategy to improve immune response against dengue in mice. Viral Immunology 18 (2005) 709-721
16. Kimura-Kuroda J., and Yasui K. Protection of mice against Japanese encephalitis virus by passive administration with monoclonal antibodies. Journal of Immunology 141 (1988) 3606-3610
17. Zhang M.J., Wang M.J., Jiang S.Z., and Ma W.Y. Passive protection of mice, goats, and monkeys against Japanese encephalitis with monoclonal antibodies. Journal of Medical Virology 29 (1989) 133-138
18. Kaufman B.M., Summers P.L., Dubois D.R., Cohen W.H., Gentry M.K., Timchak R.L., et al. Monoclonal antibodies for dengue virus prM glycoprotein protect mice against lethal dengue infection. American Journal of Tropical Medicine and Hygiene 41 (1989) 576-580
19. Henchal E.A., Henchal L.S., and Schlesinger J.J. Synergistic interactions of anti-NS1 monoclonal antibodies protect passively immunized mice from lethal challenge with dengue 2 virus. The Journal of General Virology 69 Pt 8 (1988) 2101-2107
20. Xu R., Megati S., Roopchand V., Luckay A., Masood A., Garcia-Hand D., et al. Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines. Vaccine 26 (2008) 4819-4829
21. Zhang X., Divangahi M., Ngai P., Santosuosso M., Millar J., Zganiacz A., et al. Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene. Vaccine 25 (2007) 1342-1352
22. Follador I., Araujo C., Orge G., Cheng L.H., de Carvalho L.P., Bacellar O., et al. Immune responses to an inactive vaccine against American cutaneous leishmaniasis together with granulocyte-macrophage colony-stimulating factor. Vaccine 20 (2002) 1365-1368
23. Chen Z., Sahashi Y., Matsuo K., Asanuma H., Takahashi H., Iwasaki T., et al. Comparison of the ability of viral protein-expressing plasmid DNAs to protect against influenza. Vaccine 16 (1998) 1544-1549
24. Lee S.W., Cho J.H., and Sung Y.C. Optimal induction of hepatitis C virus envelope-specific immunity by bicistronic plasmid DNA inoculation with the granulocyte-macrophage colony-stimulating factor gene. Journal of Virology 72 (1998) 8430-8436
25. Chang S.Y., Lee K.C., Ko S.Y., Ko H.J., and Kang C.Y. Enhanced efficacy of DNA vaccination against Her-2/neu tumor antigen by genetic adjuvants. International Journal of Cancer 111 (2004) 86-95
26. Yang B., Lan X., Li X., Yin X., Li B., Han X., et al. A novel bi-functional DNA vaccine expressing VP1 protein and producing antisense RNA targeted to 5′UTR of foot-and-mouth disease virus can induce both rapid inhibitory effect and specific immune response in mice. Vaccine 26 (2008) 5477-5483
27. Chen H.W., Pan C.H., Huan H.W., Liau M.Y., Chiang J.R., and Tao M.H. Suppression of immune response and protective immunity to a Japanese encephalitis virus DNA vaccine by coadministration of an IL-12-expressing plasmid. Journal of Immunology 166 (2001) 7419-7426
28. Konishi E., Yamaoka M., Khin Sane W., Kurane I., Takada K., and Mason P.W. The anamnestic neutralizing antibody response is critical for protection of mice from challenge following vaccination with a plasmid encoding the Japanese encephalitis virus premembrane and envelope genes. Journal of Virology 73 (1999) 5527-5534
29. Bokisch V.A., Top Jr. F.H., Russell P.K., Dixon F.J., and Muller-Eberhard H.J. The potential pathogenic role of complement in dengue hemorrhagic shock syndrome. New England Journal of Medicine 289 (1973) 996-1000
30. Halstead S.B. Pathogenesis of dengue: challenges to molecular biology. Science 239 (1988) 476-481
31. Qin L., Greenland J.R., Moriya C., Cayabyab M.J., and Letvin N.L. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo. Journal of Virology 81 (2007) 10606-10613
32. Ashok M.S., and Rangarajan P.N. Protective efficacy of a plasmid DNA encoding Japanese encephalitis virus envelope protein fused to tissue plasminogen activator signal sequences: studies in a murine intracerebral virus challenge model. Vaccine 20 (2002) 1563-1570
33. Bharati K., Appaiahgari M.B., and Vrati S. Effect of cytokine-encoding plasmid delivery on immune response to Japanese encephalitis virus DNA vaccine in mice. Microbiology and Immunology 49 (2005) 349-353
34. Zhai Y.Z., Li X.M., Zhou Y., Ma L., and Feng G.H. Intramuscular immunization with a plasmid DNA vaccine encoding prM-E protein from Japanese encephalitis virus: enhanced immunogenicity by co-administration of GM-CSF gene and genetic fusions of prM-E protein and GM-CSF. Intervirology 52 (2009) 152-163
35. Sun X., Hodge L.M., Jones H.P., Tabor L., and Simecka J.W. Co-expression of granulocyte-macrophage colony-stimulating factor with antigen enhances humoral and tumor immunity after DNA vaccination. Vaccine 20 (2002) 1466-1474
36. Xiang Z., and Ertl H.C. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 2 (1995) 129-135
37. Hughes H.P. Cytokine adjuvants: lessons from the past-guidelines for the future?. Veterinary Immunology and Immunopathology 63 (1998) 131-138