메뉴 건너뛰기




Volumn 11, Issue 3, 2010, Pages 357-364

RVX-208, a stimulator of apolipoprotein AI gene expression for the treatment of cardiovascular diseases

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ANTILIPEMIC AGENT; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; QUINAZOLINONE DERIVATIVE; RESVERATROL; RVX 208; UNCLASSIFIED DRUG;

EID: 77649168189     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (33)

References (50)
  • 6
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease
    • The Framingham Study
    • High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR AM J MED 1977 62 5 707-714
    • (1977) AM J MED , vol.62 , Issue.5 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 7
    • 77649098532 scopus 로고    scopus 로고
    • Annual information form
    • Resverlogix Corp. December 03
    • Annual information form. Resverlogix Corp ANNUAL REPORT 2004 December 03
    • (2004) ANNUAL REPORT
  • 8
    • 77649131411 scopus 로고    scopus 로고
    • In interests of patient safety, Pfizer stops all torcetrapib clinical trials; Company has notified FDA and is in the process of notifying all clinical investigators and other regulatory authorities
    • Pfizer Inc. December 02
    • In interests of patient safety, Pfizer stops all torcetrapib clinical trials; company has notified FDA and is in the process of notifying all clinical investigators and other regulatory authorities. Pfizer Inc PRESS RELEASE 2006 December 02
    • (2006) PRESS RELEASE
  • 9
    • 77649173571 scopus 로고    scopus 로고
    • Resverlogix RVX-208 passes key toxicology milestone
    • Resverlogix Corp. March 07
    • Resverlogix RVX-208 passes key toxicology milestone. Resverlogix Corp PRESS RELEASE 2007 March 07
    • (2007) PRESS RELEASE
  • 12
    • 77649093386 scopus 로고    scopus 로고
    • Tredaptive (nicotinic acid /laropiprant) approved in the European Union: New lipid-modifying therapy to treat LDL-C, HDL-C and triglycerides
    • Merck & Co Inc. July 11
    • Tredaptive (nicotinic acid /laropiprant) approved in the European Union: New lipid-modifying therapy to treat LDL-C, HDL-C and triglycerides. Merck & Co Inc PRESS RELEASE 2008 July 11
    • (2008) PRESS RELEASE
  • 15
    • 77649086890 scopus 로고    scopus 로고
    • RVX-208 exploratory study illustrates early potential for Alzheimer's disease
    • Resverlogix Corp. November 10
    • RVX-208 exploratory study illustrates early potential for Alzheimer's disease. Resverlogix Corp PRESS RELEASE 2008 November 10
    • (2008) PRESS RELEASE
  • 17
    • 77649086378 scopus 로고    scopus 로고
    • Resverlogix provides quarterly update
    • Resverlogix Corp. April 28
    • Resverlogix provides quarterly update. Resverlogix Corp PRESS RELEASE 2009 April 28
    • (2009) PRESS RELEASE
  • 18
    • 67649361967 scopus 로고    scopus 로고
    • American College of cardiology-58th annual scientific session
    • American College of Cardiology-58th annual scientific session. Wong NCW IDRUGS 2009 12 5 291-293
    • (2009) IDRUGS , vol.12 , Issue.5 , pp. 291-293
    • Wong, N.C.W.1
  • 19
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Inflammation, atherosclerosis, and coronary artery disease. Hansson GK N ENGL J MED 2005 352 16 1685-1695
    • (2005) N ENGL J MED , vol.352 , Issue.16 , pp. 1685-1695
    • Hansson, G.K.1
  • 20
    • 77649088920 scopus 로고    scopus 로고
    • Resverlogix phase 1b/2a study meets primary endpoint
    • Resverlogix Corp. August 25
    • Resverlogix phase 1b/2a study meets primary endpoint. Resverlogix Corp PRESS RELEASE 2009 August 25
    • (2009) PRESS RELEASE
  • 21
    • 77649128591 scopus 로고    scopus 로고
    • Resverlogix RVX-208 second clinical trial demonstrates success on key reverse cholesterol transport markers
    • Resverlogix Corp. September 29
    • Resverlogix RVX-208 second clinical trial demonstrates success on key reverse cholesterol transport markers. Resverlogix Corp PRESS RELEASE 2009 September 29
    • (2009) PRESS RELEASE
  • 22
    • 79952729023 scopus 로고    scopus 로고
    • Oral administration of compound RVX-208 increases serum levels of apoA-I and improves high-density lipoproteinmediated cholesterol efflux in African green monkeys
    • Oral administration of compound RVX-208 increases serum levels of apoA-I and improves high-density lipoproteinmediated cholesterol efflux in African green monkeys. Krimbou L, Jahagirdar R, Ruel I, Johansson J, Genest J CIRCULATION 2007 116 16 Abs 679
    • (2007) CIRCULATION , vol.116 , Issue.16 , pp. 679
    • Krimbou, L.1    Jahagirdar, R.2    Ruel, I.3    Johansson, J.4    Genest, J.5
  • 28
    • 77649089513 scopus 로고    scopus 로고
    • RVX-208 increases APOA-I, pre-B-HDL, HDL functionality and inhibits markers of inflammation
    • RVX-208 increases APOA-I, pre-B-HDL, HDL functionality and inhibits markers of inflammation. A Gordon, S Attwell, R Jahagirdar, N Wong ATHEROSCLEROSIS SUPPL 2009 10 2 Abs S4-2
    • (2009) ATHEROSCLEROSIS SUPPL , vol.10 , Issue.2
    • Gordon, A.1    Attwell, S.2    Jahagirdar, R.3    Wong, N.4
  • 29
    • 77649177617 scopus 로고    scopus 로고
    • Resverlogix updates shareholders on accelerated clinical trial plan
    • Resverlogix Corp. October 16
    • Resverlogix updates shareholders on accelerated clinical trial plan. Resverlogix Corp PRESS RELEASE 2009 October 16
    • (2009) PRESS RELEASE
  • 30
    • 77649137101 scopus 로고    scopus 로고
    • Merck's investigational anacetrapib phase IIb study results presented at American Heart Association Annual Scientific Sessions
    • Merck & Co Inc. November 17
    • Merck's investigational anacetrapib phase IIb study results presented at American Heart Association Annual Scientific Sessions. Merck & Co Inc PRESS RELEASE 2009 November 17
    • (2009) PRESS RELEASE
  • 31
    • 71249116819 scopus 로고    scopus 로고
    • Coronary artery disease-Eighth international congress from prevention to intervention
    • Coronary artery disease-Eighth international congress. From prevention to intervention. Wong NCW IDRUGS 2009 12 12 742-746
    • (2009) IDRUGS , vol.12 , Issue.12 , pp. 742-746
    • Wong, N.C.W.1
  • 32
    • 77649130910 scopus 로고    scopus 로고
    • American Heart association scientific sessions, in brief
    • American Heart Association Scientific Sessions, in brief. FDC REP PINK SHEET 2009 71 47 17-18
    • (2009) FDC REP PINK SHEET , vol.71 , Issue.47 , pp. 17-18
  • 33
    • 77649145904 scopus 로고    scopus 로고
    • Resverlogix commences phase 2 Atherosclerosis clinical trial
    • Resverlogix Corp. December 22
    • Resverlogix commences phase 2 Atherosclerosis clinical trial. Resverlogix Corp PRESS RELEASE 2009 December 22
    • (2009) PRESS RELEASE
  • 34
    • 0033539313 scopus 로고    scopus 로고
    • Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: Fate of Early Lesions in Children (FELIC) study
    • Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: Fate of Early Lesions in Children (FELIC) study. Napoli C, Glass CK, Witztum JL, Deutsch R, D'Armiento FP, Palinski W LANCET 1999 354 9186 1234-1241
    • (1999) LANCET , vol.354 , Issue.9186 , pp. 1234-1241
    • Napoli, C.1    Glass, C.K.2    Witztum, J.L.3    Deutsch, R.4    D'Armiento, F.P.5    Palinski, W.6
  • 35
    • 0021261107 scopus 로고
    • Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation
    • Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation. Faggiotto A, Ross R, Harker L ARTERIOSCLEROSIS 1984 4 4 323-340 (Pubitemid 14092676)
    • (1984) Arteriosclerosis , vol.4 , Issue.4 , pp. 323-340
    • Faggiotto, A.1    Ross, R.2    Harker, L.3
  • 37
    • 60549091035 scopus 로고    scopus 로고
    • High-density lipoproteins, inflammation and oxidative stress
    • High-density lipoproteins, inflammation and oxidative stress. Tabet F, Rye KA CLIN SCI 2009 116 1-2 87-98
    • (2009) CLIN SCI , vol.116 , Issue.1-2 , pp. 87-98
    • Tabet, F.1    Rye, K.A.2
  • 39
    • 66949172751 scopus 로고    scopus 로고
    • Promoting mechanisms of vascular health circulating progenitor cells, angiogenesis, and reverse cholesterol transport
    • Promoting mechanisms of vascular health circulating progenitor cells, angiogenesis, and reverse cholesterol transport. Moreno PR, Sanz J, Fuster V J AM COLL CARDIOL 2009 53 25 2315-2323
    • (2009) J AM COLL CARDIOL , vol.53 , Issue.25 , pp. 2315-2323
    • Moreno, P.R.1    Sanz, J.2    Fuster, V.3
  • 40
    • 0027994776 scopus 로고
    • Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits
    • Recombinant apolipoprotein A-I Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits. Ameli S, Hultgardh-Nilsson A, Cercek B, Shah PK, Forrester JS, Ageland H, Nilsson J CIRCULATION 1994 90 4 1935-1941
    • (1994) CIRCULATION , vol.90 , Issue.4 , pp. 1935-1941
    • Ameli, S.1    Hultgardh-Nilsson, A.2    Cercek, B.3    Shah, P.K.4    Forrester, J.S.5    Ageland, H.6    Nilsson, J.7
  • 43
    • 0031442321 scopus 로고    scopus 로고
    • Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport
    • Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport. Jin FY, Kamanna VS, Kashyap ML ARTERIOSCLER THROMB VASC BIOL 1997 17 10 2020-2028
    • (1997) ARTERIOSCLER THROMB VASC BIOL , vol.17 , Issue.10 , pp. 2020-2028
    • Jin, F.Y.1    Kamanna, V.S.2    Kashyap, M.L.3
  • 44
    • 69849109122 scopus 로고    scopus 로고
    • Update on strategies to increase HDL quantity and function
    • Update on strategies to increase HDL quantity and function. Duffy D, Rader DJ NAT REV CARDIOL 2009 6 7 455-463
    • (2009) NAT REV CARDIOL , vol.6 , Issue.7 , pp. 455-463
    • Duffy, D.1    Rader, D.J.2
  • 45
    • 0141455881 scopus 로고    scopus 로고
    • Basic aspects of plaque vulnerability
    • Basic aspects of plaque vulnerability. Lafont A HEART 2003 89 10 1262-1267
    • (2003) HEART , vol.89 , Issue.10 , pp. 1262-1267
    • Lafont, A.1
  • 46
    • 21544467275 scopus 로고    scopus 로고
    • Pathophysiology of coronary artery disease
    • Pathophysiology of coronary artery disease. Libby P, Theroux P CIRCULATION 2005 111 25 3481-3488
    • (2005) CIRCULATION , vol.111 , Issue.25 , pp. 3481-3488
    • Libby, P.1    Theroux, P.2
  • 47
    • 58749091678 scopus 로고    scopus 로고
    • Targeting residual cardiovascular risk: Raising highdensity lipoprotein cholesterol levels
    • Targeting residual cardiovascular risk: Raising highdensity lipoprotein cholesterol levels. Hausenloy DJ, Yellon DM POSTGRAD MED J 2008 84 997 590-598
    • (2008) POSTGRAD MED J , vol.84 , Issue.997 , pp. 590-598
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 48
    • 77649134946 scopus 로고    scopus 로고
    • Annual report
    • Resverlogix Corp. October 15
    • -2009 annual report. Resverlogix Corp ANNUAL REPORT 2010 October 15
    • (2009) ANNUAL REPORT
  • 49
    • 0027161044 scopus 로고
    • Two-dimensional electrophoresis of plasma lipoproteins: Recognition of new apo A-I-containing subpopulations
    • Two-dimensional electrophoresis of plasma lipoproteins: Recognition of new apo A-I-containing subpopulations. Asztalos BF, Sloop CH, Wong L, Roheim PS BIOCHIM BIOPHYS ACTA 1993 1169 3 291-300
    • (1993) BIOCHIM BIOPHYS ACTA , vol.1169 , Issue.3 , pp. 291-300
    • Asztalos, B.F.1    Sloop, C.H.2    Wong, L.3    Roheim, P.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.