The role of mast cells in wound healing

International Wound Journal

Volumn 7, Issue 1, 2010, Pages 55-61

  Ng, Michael Fy ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Cellular proliferation; Inflammation; Mast cell; Wound healing

Indexed keywords

CHLORPHENIRAMINE; CIMETIDINE; CROMOGLYCATE DISODIUM; IMMUNOGLOBULIN E; KETOTIFEN;

CELL PROLIFERATION; CLINICAL PRACTICE; CONNECTIVE TISSUE; DISEASE ASSOCIATION; HELMINTHIASIS; HUMAN; IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; MAST CELL; MUCOSA; NONHUMAN; PRIORITY JOURNAL; REVIEW; SCAR FORMATION; SCLERODERMA; SKIN; SKIN FIBROSIS; TISSUE INJURY; WOUND CONTRACTION; WOUND HEALING;

ANIMALS; CELL PROLIFERATION; HUMANS; MAST CELLS; MODELS, ANIMAL; WOUND HEALING;

EID: 77649144115     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/j.1742-481X.2009.00651.x     Document Type: Review

References (38)

1. Hart J. Inflammation 1: its role in the healing of acute wounds. J Wound Care 2002 11 : 205 209.
2. Martin CW, Muir IFK. The role of lymphocytes in wound healing. BrJ Plast Surg 1990 43 : 655 662.
3. Boyce DE, Jones WD, Ruge F, Harding KG, Moore K. The role of lymphocytes in human dermal wound healing. Br J Dermatol 2000 143 : 59 65.
4. Ehrlich P. Beiträge zur theorie und praxis der hitologischen Färbung. Thesis, Leipzig University, 1878.
5. Metcalfe DD, Baram D, Mekori YA. Mast cells. Physiol Rev 1997 77 : 1033 1079.
6. Parslow TG, Stites DP, Terr AI, Imboden JB, editors. Medical immunology. 10th ed. London, McGraw-Hill, 2001.
7. Sonoda T, Kitamura Y, Haku Y, Hara H, Mori KJ. Mast cell precursors in various hematopoietic colonies of mice produced in vivo and in vitro. Br J Haematol 1983 53 : 611 620.
8. Woolf, N. Acute inflammation II: cellular events and chemical mediators. In: Woolf N, editor. Pathology: basic and systemic, 1st ed. London : W B Saunders, 1998 : 41 62.
9. Theoharides TC, Kempuraj D, Tagen M, Conti P, Kalogeromitros D. Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol Rev 2007 217 : 65 78.
10. Kagawa S, Matsuo A, Yagi Y, Ikematsu K, Tsuda R, Nakasono I. The time-course analysis of gene expression during wound healing in mouse skin. Legal Med 2008 11 (2 70 5.
11. Nishioka K, Kobayashi Y, Katayama I, Takijiri C. Mast cell numbers in diffuse scleroderma. Arch Dermatol 1987 123 (22 205 208.
12. Kischer CW, Bunce H, Shetlar MR. Mast cell analysis in hypertrophic scars, hypertrophic scars treated with pressure and mature scars. J Invest Dermatol 1978 70 : 355 357.
13. Soucek L, Lawlor ER, Soto D, Shchors K, Brown Swugart L, Evan GI. Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumours. Nat Med 2007 13 : 1211 1218.
14. Chang L, Wong T, Ohbayashi M, Bunce C, Barton K, Ono S, Khaw PT. Increased mast cell numbers in the conjunctiva of glaucoma patients: a possible indicator of preoperative glaucoma surgery inflammation. Eye 2009 23 : 1859 1865.
15. Kalin TV, Meliton L, Meliton AY, Zhu X, Whitsett JA, Kalinichenko VV. Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene. Am J Respir Cell Mol Biol 2008 39 : 390 399.
16. Higuchi H, Hara M, Yamamoto K, Miyamoto T, Kinoshita M, Yamada T, Uchiyama K, Matsumori A. Mast cells play a critical role in the pathogenesis of viral myocarditis. Circulation 2008 118 : 363 372.
17. Desmoulière A, Geinoz A, Gabbiani F, Gabbiani G. Transforming growth factor-β1 induces α-smooth muscle actin expression in granulation tissue myofibrobalsts and in quiescent and growing cultured fibroblasts. J Cell Biol 1993 122 : 103 111.
18. Shah M, Foreman DM, Ferguson MW. Neutralising antibody to TGF-beta 1,2 reduces cutaneous scarring in adult rodents. J Cell Sci 1994 107: 1137 1157.
19. Abe M, Kurosawa M, Ishikawa O, Miyachi Y. Effect of mast cell-derived mediators and mast cell-related neutral proteases on human dermal fibroblast proliferation and type I collagen production. J Allergy Clin Immunol 2002 106 : S78 84
20. Garbuzenko E, Nagler A, Pickholtz D, Gillery P, Reich R, Maquart F-X, Levi-Schaffer F. Human mast cells stimulate fibroblast proliferation, collagen synthesis and lattice contraction: a direct role for mast cells in skin fibrosis. Clin Exp Allergy 2002 32 : 237 246.
21. Lohi J, Narvima I, Keski-Oja J. Pericellular substrates of human mast cell tryptase: 72000 dalton gelatinase and fibronectin. J Cell Biochem 1992 106 : 337 349.
22. Miller HRP, Pemberton AD. Tissue-specific expression of mast cell granule serine proteinases and their role in inflammation in the lung and gut. Immunology 2002 105 : 375 390.
23. Henz BM. Exploring the mast cell enigma: a personal reflection of what remains to be done. Exp Dermatol 2008 17 : 91 9.
24. Solivan S, Selwood T, Wang Z-M, Schechter NM. Evidence of diversity of substrate specificity among members of the chymase family of serine proteases. FEBS 2002 512 : 133 138.
25. Gailit J, Marchese MJ, Kew RR, Gruber BL. The differentiation and function of myofibroblasts is regulated by mast cell mediators. J Invest Dermatol 2001 117 : 1113 1119.
26. Yamamoto T, Hartmann K, Eckes B, Krieg T. Mast cells enhance contraction of three-dimensional collagen lattices by fibroblasts by cell-cell interaction: role of stem cell factor/c-kit. Immunology 2000 99 : 435 439.
27. Moyer KE, Saggers GC, Ehrlich P. Mast cells promote fibroblast populated collagen lattice contraction through gap junction intercellular communication. Wound Repair Regen 2004 12 : 269 275.
28. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000 6 3: 389 396.
29. Nienartowicz A, Sobaniec-Lotowska ME, Jarocka-Cyrta E, Lemancewicz D. Mast cells in neoangiogenesis. Med Sci Monit 2006 12 : RA53 6.
30. Crivellato E, Nico B, Ribatti D. Mast cells and tumour angiogenesis: new insight from experimental carcinogenesis. Cancer Lett 2008 269 : 1 6.
31. Cox L. Present angiogenesis research and its possible future implementation in wound care. J Wound Care 2003 12 : 225 228.
32. Russo A, Russo G, Peticca M, Pietropaolo C, Di Rosa M, Iuvone T. Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: role of mast cell protease-5. Br J Pharmacol 2005 145 : 24 33.
33. Lawson JA, Adams WJ, Morris DL. Ranitidine and cimetidine differ in their in vitro and in vivo effects on human colonic cancer growth. Br J Cancer 1996 73 : 872 876.
34. Bowrey PF, King J, Magarey C, Schwartz P, Marr P, Bolton E, Morris DL. Histamine, mast cells and tumour cell proliferation in breast cancer: does preoperative cimetidine administration have an effect? Br J Cancer 2000 82 : 167 170.
35. Weller K, Foitzik K, Paus R, Syska W, Maurer M. Mast cells are required for normal healing of skin wounds in mice. FASEB 2006 20 : E1628 35.
36. Gallant-Behm CL, Hildebrand KA, Hart DA. The mast cell stabilizer ketotifen prevents development of excessive skin wound contraction and fibrosis in red Duroc pigs. Wound Repair Regen 2008 16 : 226 233.
37. Wang JF, Olson ME, Reno CR, Wright JB, Hart DA. The pig as a model for excisional skin wound healing: characterization of the molecular and cellular biology, and bacteriology of the healing process. Comp Med 2001 51 : 341 348.
38. Gallant CL, Olson ME, Hart DA. Molecular, histologic, and gross phenotype of skin wound healing in red Duroc pigs reveal an abnormal healing phenotype of hypercontracted, hyperpigmented scarring. Wound Repair Regen 2004 12 : 305 319.