Investigation of ingavirin®antiviral activity against season influenza virus A/H1N1 in MDCK Cell Culture

Antibiotiki i Khimioterapiya

Volumn 54, Issue 9-10, 2009, Pages 19-22

  Galegov, G A ^a   Andronova, V L ^a   Nebolsin, V E ^b  

^a D I IVANOVSKY INSTITUTE OF VIROLOGY   (Russian Federation)

^b Valenta Pharmacevtica   (Russian Federation)

Author keywords

Antiviral actvity; Influenza virus a h1n1; Ingavirin

Indexed keywords

ORTHOMYXOVIRIDAE;

AMIDE; ANTIVIRUS AGENT; DICARBOXYLIC ACID; IMIDAZOLE DERIVATIVE; PENTANEDIOIC ACID IMIDAZOLYL ETHANAMIDE;

ANIMAL; ANTIVIRAL RESISTANCE; ARTICLE; CELL LINE; DOG; DRUG EFFECT; INFLUENZA VIRUS A H1N1;

AMIDES; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DICARBOXYLIC ACIDS; DOGS; DRUG RESISTANCE, VIRAL; IMIDAZOLES; INFLUENZA A VIRUS, H1N1 SUBTYPE;

EID: 77649113806     PISSN: 02352990     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. http://ecdc.europa.eu/en/files/pdf/Health-topics/Situation-Report-090725- 1700hrs.pdf.
2. Gubareva L. V., Kaiser L., Hayden F. G. Influenza virus neuraminidase inhibitors. Lancet 2000; 355: 627-835.
3. Bright R. A., Medina M. J., Xu X. et al. Incidence of amantadine resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 2005; 366:1175-1181.
4. Bright R. A., Shay D. K, Shay B. et al. Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. JAMA 2006; 295:8:891-894.
5. Lacenby A., Hungnes O., Dudmam S. G. et al. Emergence of resistance to oseltamivir among influenza A(H1N1) viruses in Europe. Eurosurveillance 2008; 13: Issue 5:8026.
6. Leneva I. el al. The mechanism of action of arbidol against influenza virus -selection and characterization of arbidol-resistant mutants. 12th International Congress of Virology. Paris, 2002; 1077: Abstr.
7. Kaverin N. V., Webster R. G. Impairment of multicycle influenza virus growth in Ver (WHO) cells by loss of trypsin activity. J Virol 1995; 69:4: 2700-2703.