Simultaneous quantitative determination of olmesartan and hydrochlorothiazide in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 9-10, 2010, Pages 743-748

  Liu, Dongyang ^a   Jiang, Ji ^a   Wang, Peng ^a   Feng, Sheng ^a   Hu, Pei ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Determination; HPLC MS MS; Human plasma and urine; Hydrochlorothiazide; Olmesartan; Simultaneous

Indexed keywords

ANALYTES; BIOLOGICAL MATRIXES; CONCENTRATION RANGES; EXTRACTION RECOVERY; HPLC-MS/MS; HUMAN PLASMAS; HYDROCHLOROTHIAZIDE; ISOCRATIC ELUTION; LIQUID CHROMATOGRAPHY COUPLED TO TANDEM MASS SPECTROMETRY; MATRIX EFFECTS; MULTIPLE-REACTION MONITORING MODES; QUANTITATIVE DETERMINATIONS; RAPID METHOD; SIMULTANEOUS DETERMINATIONS; SOLID-PHASE EXTRACTION; TRIPLE QUADRUPOLE;

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS; RECOVERY;

PLASMA STABILITY;

HYDROCHLOROTHIAZIDE; OLMESARTAN;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG URINE LEVEL; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINALYSIS;

ANTIHYPERTENSIVE AGENTS; CHROMATOGRAPHY, LIQUID; HUMANS; HYDROCHLOROTHIAZIDE; IMIDAZOLES; TANDEM MASS SPECTROMETRY; TETRAZOLES;

EID: 77549088148     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.01.009     Document Type: Article

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