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Volumn 878, Issue 9-10, 2010, Pages 823-830
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Simultaneous determination of etoposide and a piperine analogue (PA-1) by UPLC-qTOF-MS: Evidence that PA-1 enhances the oral bioavailability of etoposide in mice
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Author keywords
Bioavailability; Etoposide; Pharmacokinetics; Piperine analogue; UPLC qTOF MS MS
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Indexed keywords
ANALYTES;
AUTOSAMPLERS;
BIOAVAILABILITY;
CALIBRATION CURVES;
CONCENTRATION RANGES;
ETOPOSIDE;
FREEZE-THAW;
IN-BETWEEN;
LOWER LIMIT OF QUANTITATIONS;
METHANOL-WATER;
MOBILE PHASE;
MOUSE PLASMA;
MULTIPLE-REACTION MONITORING MODES;
PHARMACOKINETIC STUDIES;
REVERSE PHASE;
ROOM TEMPERATURE;
RUNTIMES;
SIMULTANEOUS DETERMINATIONS;
SOLID PHASE EXTRACTION TECHNIQUES;
CHEMICAL ANALYSIS;
EXTRACTION;
IONIZATION OF LIQUIDS;
METHANOL;
PHARMACOKINETICS;
BIOCHEMISTRY;
4 ETHYL 5(3,4 METHYLENEDIOXYPHENYL) 2E,4E PENTADIENOIC ACID PIPERIDINE;
ETOPOSIDE;
PA 1;
PIPERINE;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
DISTRIBUTION VOLUME;
DRUG BIOAVAILABILITY;
DRUG CLEARANCE;
DRUG DETERMINATION;
DRUG HALF LIFE;
DRUG POTENTIATION;
ELECTROSPRAY MASS SPECTROMETRY;
LIQUID CHROMATOGRAPHY;
MAXIMUM PLASMA CONCENTRATION;
MOUSE;
NONHUMAN;
PRIORITY JOURNAL;
SOLID PHASE EXTRACTION;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ALKALOIDS;
ANIMALS;
ANTINEOPLASTIC AGENTS, PHYTOGENIC;
BENZODIOXOLES;
BIOLOGICAL AVAILABILITY;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG CARRIERS;
ETOPOSIDE;
MICE;
PIPERIDINES;
POLYUNSATURATED ALKAMIDES;
TANDEM MASS SPECTROMETRY;
MUS;
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EID: 77549085128
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.01.048 Document Type: Article |
Times cited : (32)
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References (21)
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