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Volumn 877, Issue 30, 2009, Pages 3781-3786
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Quantitative determination of icotinib in human plasma and urine using liquid chromatography coupled to tandem mass spectrometry
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Author keywords
Human plasma and urine; Icotinib; Quantitative determination
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Indexed keywords
CLINICAL PHARMACOKINETICS;
ELECTROSPRAY IONIZATION SOURCES;
GRADIENT ELUTION;
HEALTHY SUBJECTS;
HPLC-MS/MS;
HUMAN PLASMAS;
INTERNAL STANDARDS;
LIQUID CHROMATOGRAPHY COUPLED TO TANDEM MASS SPECTROMETRY;
LIQUID-LIQUID EXTRACTION;
LOWER LIMITS OF QUANTITATIONS;
MATRIX EFFECTS;
MIDAZOLAM;
POSITIVE MODE;
QUANTITATIVE DETERMINATIONS;
REACTION MONITORING;
SENSITIVE METHOD;
VALIDATION RESULTS;
BODY FLUIDS;
CHROMATOGRAPHIC ANALYSIS;
CHROMATOGRAPHY;
ELECTROSPRAY IONIZATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
IONIZATION;
LIQUIDS;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
PARTICLE DETECTORS;
PLASMA (HUMAN);
PLASMAS;
SOLVENT EXTRACTION;
PLASMA STABILITY;
ICOTINIB;
MIDAZOLAM;
QUINAZOLINE DERIVATIVE;
UNCLASSIFIED DRUG;
ACCURACY;
ARTICLE;
DILUTION;
DRUG BLOOD LEVEL;
DRUG ISOLATION;
DRUG URINE LEVEL;
ELECTROSPRAY;
ELUTION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
LIQUID LIQUID EXTRACTION;
PRIORITY JOURNAL;
QUANTITATIVE ASSAY;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
ANTINEOPLASTIC AGENTS;
CHROMATOGRAPHY, LIQUID;
CROWN ETHERS;
HUMANS;
QUINAZOLINES;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
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EID: 72049103970
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2009.08.055 Document Type: Article |
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Times cited : (37)
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References (16)
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