Stroke-induced immunodepression is a marker of severe brain damage

Stroke

Volumn 41, Issue 2, 2010, Pages

  Urra, Xabier ^a   Chamorro, Ángel ^a,b,c  

^a HOSPITAL CLÍNIC   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; HLA DR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER;

BRAIN DAMAGE; BRAIN INFARCTION SIZE; CELL COUNT; CYTOKINE PRODUCTION; DISEASE SEVERITY; HUMAN; IMMUNE DEFICIENCY; INFECTION; INFECTION RISK; LETTER; MONOCYTE; PRIORITY JOURNAL; BLOOD; BRAIN INFARCTION; COMORBIDITY; DISEASE COURSE; HOSPITALIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; NOTE; PATHOLOGY; PATHOPHYSIOLOGY; PROGNOSIS; RISK FACTOR; STROKE;

ANTI-BACTERIAL AGENTS; BIOLOGICAL MARKERS; BRAIN INFARCTION; COMORBIDITY; DISEASE PROGRESSION; HLA-DR ANTIGENS; HUMANS; IMMUNE TOLERANCE; INFECTION; MONOCYTES; PROGNOSIS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STROKE;

EID: 77449145607     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.109.566968     Document Type: Letter

References (7)

1. Meisel C, Schwab JM, Prass K, Meisel A, Dirnagl U. Central nervous system injury-induced immune deficiency syndrome. Nat Rev Neurosci. 2005;6:775-786.
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3. Hug A, Dalpke A, Wieczorek N, Giese T, Lorenz A, Auffarth G, Liesz A, Veltkamp R. Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection. Stroke. 2009;40:3226-3232.
4. Urra X, Cervera A, Villamor N, Planas AM, Chamorro A. Harms and benefits of lymphocyte subpopulations in patients with acute stroke. Neuroscience. 2009;158:1174-1183.
5. Vargas M, Horcajada JP, Obach V, Revilla M, Cervera A, Torres F, Planas AM, Mensa J, Chamorro A. Clinical consequences of infection in patients with acute stroke: is it prime time for further antibiotic trials? Stroke. 2006;37:461-465.
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7. Urra X, Villamor N, Amaro S, Gomez-Choco M, Obach V, Oleaga L, Planas AM, Chamorro A. Monocyte subtypes predict clinical course and prognosis in human stroke. J Cereb Blood Flow Metab. 2009;29: 994-1002.