-
1
-
-
77952118055
-
-
PREZISTA TM (darunavir) , Tibotec Inc. (accessed 19 , 2009)
-
PREZISTA TM (darunavir) Summary of Product Characteristics, 2009, Tibotec Inc. http:// www.emea.europa.eu/humandocs/PDFs/ EPAR/prezista/emea-combined- h707en.pdf (accessed 19 November 2009).
-
(2009)
Summary of Product Characteristics
-
-
-
2
-
-
77951025065
-
-
Tibotec Inc. ( accessed 19 November 2009)
-
PREZISTA TM (darunavir) US Prescribing Information; revised June 2009. Tibotec Inc. http://www.prezista.com/prezista/documents/ us-package-insert.pdf. (accessed 19 November 2009).
-
(2009)
US Prescribing Information; Revised June
-
-
-
3
-
-
19544386471
-
TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates
-
DOI 10.1128/AAC.49.6.2314-2321.2005
-
De Meyer S, Azijn H, Surleraux D, et al: TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates. Antimicrob Agents Chemother 2005; 49: 2314-2321. (Pubitemid 40734460)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.6
, pp. 2314-2321
-
-
De Meyer, S.1
Azijn, H.2
Surleraux, D.3
Jochmans, D.4
Tahri, A.5
Pauwels, R.6
Wigerinck, P.7
De Bethune, M.-P.8
-
4
-
-
34249322174
-
Absolute bioavailability of TMC114 administered in the absence and presence of low-dose ritonavir
-
Sekar V, Guzman S, Stevens T, et al: Absolute bioavailability of TMC114 administered in the absence and presence of low-dose ritonavir. 7th International Workshop on Clinical Pharmacology of HIV Therapy, Lisbon, 2006, abstr 86.
-
(2006)
7th International Workshop on Clinical Pharmacology of HIV Therapy, Lisbon
-
-
Sekar, V.1
Guzman, S.2
Stevens, T.3
-
5
-
-
0003443998
-
-
Crixivanα(indinavir) revised 7 October Merck Sharp & Dohme Ltd (accessed 29 April 2008)
-
Crixivanα(indinavir) Summary of Product Characteristics, revised 7 October 2006. Merck Sharp & Dohme Ltd. http://www. emea.europa.eu/humandocs/ PDFs/EPAR/ Crixivan/H-128-PI-en.pdf (accessed 29 April 2008).
-
(2006)
Summary of Product Characteristics
-
-
-
6
-
-
0034801355
-
Pharmacokinetic profile and tolerability of indinavir-ritonavir combinations in healthy volunteers
-
DOI 10.1128/AAC.45.10.2710-2715.2001
-
Saah AJ, Winchell GA, Nessly ML, et al: Pharmacokinetic profile and tolerability of indinavir-ritonavir combinations in healthy volunteers. Antimicrob Agents Chemother 2001; 45: 2710-2715. (Pubitemid 32906661)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.10
, pp. 2710-2715
-
-
Saah, A.J.1
Winchell, G.A.2
Nessly, M.L.3
Seniuk, M.A.4
Rhodes, R.R.5
Deutsch, P.J.6
-
8
-
-
1542405937
-
Pharmacokinetic Considerations for Combining 2 Protease Inhibitors
-
Boffito M, Moyle GJ: Pharmacokinetic considerations for combining 2 protease inhibitors. AIDS Read 2004; 14: 110-112, 115-116. (Pubitemid 38339411)
-
(2004)
AIDS Reader
, vol.14
, Issue.3
, pp. 110-112
-
-
Boffito, M.1
Moyle, G.J.2
-
9
-
-
0003443998
-
-
Norvirα(ritonavir) Abbott Laboratories L., UK. (accessed 29 April 2008)
-
Norvirα(ritonavir) Summary of Product Characteristics; revised 27 August 2006, Abbott Laboratories L., UK. http://www.emea. europa.eu/humandocs/ PDFs/EPAR/Norvir/ H-127-PI-en.pdf (accessed 29 April 2008).
-
(2006)
Summary of Product Characteristics; Revised 27 August
-
-
-
10
-
-
60349115344
-
Cocktail study to investigate the in-vivo drug interaction potential of darunavir coadministered with low-dose ritonavir (DRV/ r; RTV) on cytochrome P450 enzymes 2D6, 2C9 and 2C19
-
New Orleans
-
Sekar V, Spinosa-Guzman S, Meyvisch P, et al: Cocktail study to investigate the in-vivo drug interaction potential of darunavir coadministered with low-dose ritonavir (DRV/ r; RTV) on cytochrome P450 enzymes 2D6, 2C9 and 2C19. 9th International Workshop on Clinical Pharmacology of HIV Therapy (IWCPHIV), New Orleans, 2008, abstr P23.
-
(2008)
9th International Workshop on Clinical Pharmacology of HIV Therapy (IWCPHIV)
-
-
Sekar, V.1
Spinosa-Guzman, S.2
Meyvisch, P.3
-
11
-
-
77951022980
-
Swift and simultaneous determination of darunavir (TMC114) and ritonavir in human plasma using LC-MS/MS. 17th Int Mass Spectrom Conf (IMSC), Prague
-
Bouche MP, Michielsen L, Piot M, et al: Swift and simultaneous determination of darunavir (TMC114) and ritonavir in human plasma using LC-MS/MS. 17th Int Mass Spectrom Conf (IMSC), Prague, 2006, abstr TuP-042.
-
(2006)
Abstr TuP-042
-
-
Bouche, M.P.1
Michielsen, L.2
Piot, M.3
-
12
-
-
77951022574
-
-
Data on File. Tibotec Inc
-
Data on File. Tibotec Inc.
-
-
-
-
13
-
-
0015356770
-
The use of nonparametric methods in the statistical analysis of the two-period change-over design
-
Koch G: The use of nonparametric methods in the statistical analysis of the two-period change-over design. Biometrics 1972; 28: 577-584.
-
(1972)
Biometrics
, vol.28
, pp. 577-584
-
-
Koch, G.1
-
14
-
-
1642363348
-
Analysis of protease inhibitor combinations in vitro: Activity of lopinavir, amprenavir and tipranavir against HIV type 1 wild-type and drug-resistant isolates
-
DOI 10.1093/jac/dkh103
-
Bulgheroni E, Citterio P, Croce F, et al: Analysis of protease inhibitor combinations in vitro: activity of lopinavir, amprenavir and tipranavir against HIV type 1 wild-type and drug-resistant isolates. J Antimicrob Chemother 2004; 53: 464-468. (Pubitemid 38380244)
-
(2004)
Journal of Antimicrobial Chemotherapy
, vol.53
, Issue.3
, pp. 464-468
-
-
Bulgheroni, E.1
Citterio, P.2
Croce, F.3
Lo Cicero, M.4
Vigano, O.5
Soster, F.6
Chou, T.-C.7
Galli, M.8
Rusconi, S.9
-
15
-
-
17544368645
-
The pharmacokinetics of HIV protease inhibitor combinations
-
Boffito M, Maitland D, Samarasinghe Y, et al: The pharmacokinetics of HIV protease inhibitor combinations. Curr Opin Infect Disease 2005; 18: 1-7. (Pubitemid 41716233)
-
(2005)
Current Opinion in Infectious Diseases
, vol.18
, Issue.1
, pp. 1-7
-
-
Boffito, M.1
Maitland, D.2
Samarasinghe, Y.3
Pozniak, A.4
-
16
-
-
13244299389
-
Pharmacokinetics and safety of tipranavir/ritonavir (TPV/r) alone or in combination with saquinavir (SQV), amprenavir (APV), or lopinavir (LPV): Interim analysis of BI1182.51
-
Bangkok, abstr WeOrB1236
-
Walmsley S, Leith J, Katlama C, et al: Pharmacokinetics and safety of tipranavir/ritonavir (TPV/r) alone or in combination with saquinavir (SQV), amprenavir (APV), or lopinavir (LPV): interim analysis of BI1182.51. 15th International AIDS Conference, Bangkok, 2004, abstr WeOrB1236.
-
(2004)
15th International AIDS Conference
-
-
Walmsley, S.1
Leith, J.2
Katlama, C.3
-
17
-
-
20144365012
-
Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results
-
Kashuba AD, Tierney C, Downey GF, et al: Combining fosamprenavir with lopinavir/ ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results. AIDS 2005; 19: 145-152. (Pubitemid 40409533)
-
(2005)
AIDS
, vol.19
, Issue.2
, pp. 145-152
-
-
Kashuba, A.D.M.1
Tierney, C.2
Downey, G.F.3
Acosta, E.P.4
Vergis, E.N.5
Klingman, K.6
Mellors, J.W.7
Eshleman, S.H.8
Scott, T.R.9
Collier, A.C.10
-
18
-
-
12144286333
-
Saquinavir drug exposure is not impaired by the boosted double protease inhibitor combination of lopinavir/ritonavir
-
DOI 10.1097/00002030-200402200-00017
-
Stephan C, Hentig N, Kourbeti I, et al: Saquinavir drug exposure is not impaired by the boosted double protease inhibitor combination of lopinavir/ritonavir. AIDS 2004; 18: 503-508. (Pubitemid 38365878)
-
(2004)
AIDS
, vol.18
, Issue.3
, pp. 503-508
-
-
Stephan, C.1
Hentig, N.V.2
Kourbeti, I.3
Dauer, B.4
Mosch, M.5
Lutz, T.6
Klauke, S.7
Harder, S.8
Kurowski, M.9
Staszewski, S.10
-
19
-
-
7244243920
-
Steady-state pharmacokinetics of a double-boosting regimen of saquinavir soft gel plus lopinavir plus minidose ritonavir in human immunodeficiency virus-infected adults
-
DOI 10.1128/AAC.48.11.4256-4262.2004
-
Ribera E, Lopez RM, Diaz M, et al: Steadystate pharmacokinetics of a double-boosting regimen of saquinavir soft gel plus lopinavir plus minidose ritonavir in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother 2004; 48: 4256-4262. (Pubitemid 39434884)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.11
, pp. 4256-4262
-
-
Ribera, E.1
Lopez, R.M.2
Diaz, M.3
Pou, L.4
Ruiz, L.5
Falco, V.6
Crespo, M.7
Azuaje, C.8
Ruiz, I.9
Ocana, I.10
Clotet, B.11
Pahissa, A.12
-
20
-
-
33748745128
-
Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV type 1-infected individuals administered different atazanavir doses
-
DOI 10.1089/aid.2006.22.749
-
Boffito M, Maitland D, Dickinson L, et al: Pharmacokinetics of saquinavir hard gel (SQV)/ritonavir and atazanavir when combined once daily in HIV type 1-infected individuals administered different atazanavir doses. AIDS Res Hum Retrovir 2006; 22: 749-756. (Pubitemid 44735001)
-
(2006)
AIDS Research and Human Retroviruses
, vol.22
, Issue.8
, pp. 749-756
-
-
Boffito, M.1
Maitland, D.2
Dickinson, L.3
Back, D.4
Hill, A.5
Fletcher, C.6
Moyle, G.7
Nelson, M.8
Gazzard, B.9
Pozniak, A.10
-
21
-
-
3042636428
-
Atazanavir enhances saquinavir hard-gel concentrations in a ritonavir-boosted once-daily regimen
-
DOI 10.1097/00002030-200406180-00007
-
Boffito M, Kurowski M, Kruse G, et al: Atazanavir enhances saquinavir hard-gel concentrations in a ritonavir-boosted once-daily regimen. AIDS 2004; 18: 1291-1297. (Pubitemid 38822707)
-
(2004)
AIDS
, vol.18
, Issue.9
, pp. 1291-1297
-
-
Boffito, M.1
Kurowski, M.2
Kruse, G.3
Hill, A.4
Benzie, A.A.5
Nelson, M.R.6
Moyle, G.J.7
Gazzard, B.G.8
Pozniak, A.L.9
-
22
-
-
0029872126
-
Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor
-
Chiba M, Hensleigh M, Nishime JA, Balani SK, Lin JH: Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor. Drug Metab Dispos 1996; 24: 307-314. (Pubitemid 26087084)
-
(1996)
Drug Metabolism and Disposition
, vol.24
, Issue.3
, pp. 307-314
-
-
Chiba, M.1
Hensleigh, M.2
Nishime, J.A.3
Balani, S.K.4
Lin, J.H.5
-
23
-
-
0033371825
-
Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors
-
DOI 10.1097/00002030-199909100-00004
-
Profit L, Eagling V, Back D: Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. AIDS 1999; 13: 1623-1627. (Pubitemid 30015708)
-
(1999)
AIDS
, vol.13
, Issue.13
, pp. 1623-1627
-
-
Profit, L.1
Eagling, V.A.2
Back, D.J.3
-
24
-
-
52949129506
-
Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements
-
Jiménez-Nácher I, García B, Barreiro P, et al: Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements. J Antimicrob Chemother 2008; 62: 816-822
-
(2008)
J Antimicrob Chemother
, vol.62
, pp. 816-822
-
-
Jiménez-Nácher, I.1
García, B.2
Barreiro, P.3
-
25
-
-
34147107862
-
Pharmacokinetic/ pharmacodynamic (PK/ PD) analyses of TMC114 in the POWER 1 and POWER 2 trials in treatment-experienced HIV-infected patients
-
Abstr J-121
-
Sekar V, de Meyer S, Vangeneugden T, et al: Pharmacokinetic/ pharmacodynamic (PK/ PD) analyses of TMC114 in the POWER 1 and POWER 2 trials in treatment-experienced HIV-infected patients. Conference on Retroviruses and Opportunistic Infections (CROI), Denver, 2006, abstr J-121.
-
(2006)
Conference on Retroviruses and Opportunistic Infections (CROI) Denver
-
-
Sekar, V.1
De Meyer, S.2
Vangeneugden, T.3
|