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Volumn 208, Issue 2, 2010, Pages 223-232

Effects of acute tryptophan depletion in serotonin reuptake inhibitor-remitted patients with generalized anxiety disorder

Author keywords

Anxiety; GAD; Serotonin; SSRI; Tryptophan

Indexed keywords

AMINO ACID TRANSPORTER; ESCITALOPRAM; PAROXETINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRYPTOPHAN; VENLAFAXINE; AMINO ACID; ANXIOLYTIC AGENT; CARBON DIOXIDE;

EID: 77449130264     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-009-1722-1     Document Type: Article
Times cited : (17)

References (45)
  • 3
    • 58649084786 scopus 로고    scopus 로고
    • Effect of acute tryptophan depletion on noradrenaline and dopamine in the rat brain
    • 10.1177/0269881108089597 1:CAS:528:DC%2BD1MXisVClu7o%3D 18562433
    • T Ardis M Cahir J Elliott R Bell G Reynolds S Cooper 2009 Effect of acute tryptophan depletion on noradrenaline and dopamine in the rat brain J Psychopharmacol 23 51 55 10.1177/0269881108089597 1:CAS:528:DC%2BD1MXisVClu7o%3D 18562433
    • (2009) J Psychopharmacol , vol.23 , pp. 51-55
    • Ardis, T.1    Cahir, M.2    Elliott, J.3    Bell, R.4    Reynolds, G.5    Cooper, S.6
  • 5
    • 4644308951 scopus 로고    scopus 로고
    • Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder
    • 10.1016/j.biopsych.2004.07.006 1:CAS:528:DC%2BD2cXnvV2ms7w%3D 15450786
    • SV Argyropoulos SD Hood M Adrover CJ Bell AS Rich JR Nash NC Rich HJ Witchel DJ Nutt 2004 Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder Biol Psychiatry 56 503 509 10.1016/j.biopsych.2004.07.006 1:CAS:528: DC%2BD2cXnvV2ms7w%3D 15450786
    • (2004) Biol Psychiatry , vol.56 , pp. 503-509
    • Argyropoulos, S.V.1    Hood, S.D.2    Adrover, M.3    Bell, C.J.4    Rich, A.S.5    Nash, J.R.6    Rich, N.C.7    Witchel, H.J.8    Nutt, D.J.9
  • 7
    • 33845738916 scopus 로고    scopus 로고
    • 2 model of GAD using paroxetine and lorazepam in healthy volunteers
    • 10.1177/0269881106063889 1:CAS:528:DC%2BD2sXhvFylsbc%3D 16533865
    • 2 model of GAD using paroxetine and lorazepam in healthy volunteers J Psychopharmacol 21 42 49 10.1177/0269881106063889 1:CAS:528:DC%2BD2sXhvFylsbc%3D 16533865
    • (2007) J Psychopharmacol , vol.21 , pp. 42-49
    • Bailey, J.E.1    Kendrick, A.2    Diaper, A.3    Potokar, J.P.4    Nutt, D.J.5
  • 8
    • 27644534854 scopus 로고    scopus 로고
    • Evidence-based guidelines for the pharmacological treatment of anxiety disorders: Recommendations from the British Association for Psychopharmacology
    • 10.1177/0269881105059253 1:CAS:528:DC%2BD2MXht1Kru77N 16272179
    • DS Baldwin IM Anderson DJ Nutt B Bandelow A Bond JR Davidson JA Den Boer NA Fineberg M Knapp J Scott HU Wittchen 2005 Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology J Psychopharmacol 19 567 596 10.1177/0269881105059253 1:CAS:528:DC%2BD2MXht1Kru77N 16272179
    • (2005) J Psychopharmacol , vol.19 , pp. 567-596
    • Baldwin, D.S.1    Anderson, I.M.2    Nutt, D.J.3    Bandelow, B.4    Bond, A.5    Davidson, J.R.6    Den Boer, J.A.7    Fineberg, N.A.8    Knapp, M.9    Scott, J.10    Wittchen, H.U.11
  • 9
    • 0028350351 scopus 로고
    • Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors
    • 1:STN:280:DyaK2c3htlGkuw%3D%3D 8161291
    • LC Barr WK Goodman CJ McDougle PL Delgado GR Heninger DS Charney LH Price 1994 Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors Arch Gen Psychiatry 51 309 317 1:STN:280:DyaK2c3htlGkuw%3D%3D 8161291
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 309-317
    • Barr, L.C.1    Goodman, W.K.2    McDougle, C.J.3    Delgado, P.L.4    Heninger, G.R.5    Charney, D.S.6    Price, L.H.7
  • 10
    • 0035021701 scopus 로고    scopus 로고
    • Tryptophan depletion and its implications for psychiatry
    • 10.1192/bjp.178.5.399 1:STN:280:DC%2BD3Mzps1ekug%3D%3D 11331552
    • C Bell J Abrams D Nutt 2001 Tryptophan depletion and its implications for psychiatry Br J Psychiatry 178 399 405 10.1192/bjp.178.5.399 1:STN:280:DC%2BD3Mzps1ekug%3D%3D 11331552
    • (2001) Br J Psychiatry , vol.178 , pp. 399-405
    • Bell, C.1    Abrams, J.2    Nutt, D.3
  • 11
    • 0036204062 scopus 로고    scopus 로고
    • Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine
    • 10.1177/026988110201600116 1:CAS:528:DC%2BD38Xjt1yms7o%3D 11949771
    • C Bell S Forshall M Adrover J Nash S Hood S Argyropoulos A Rich DJ Nutt 2002 Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine J Psychopharmacol 16 5 14 10.1177/ 026988110201600116 1:CAS:528:DC%2BD38Xjt1yms7o%3D 11949771
    • (2002) J Psychopharmacol , vol.16 , pp. 5-14
    • Bell, C.1    Forshall, S.2    Adrover, M.3    Nash, J.4    Hood, S.5    Argyropoulos, S.6    Rich, A.7    Nutt, D.J.8
  • 12
    • 27744511322 scopus 로고    scopus 로고
    • Acute tryptophan depletion. Part II: Clinical effects and implications
    • 15996137
    • CJ Bell SD Hood DJ Nutt 2005 Acute tryptophan depletion. Part II: clinical effects and implications Aust N Z J Psychiatry 39 565 574 15996137
    • (2005) Aust N Z J Psychiatry , vol.39 , pp. 565-574
    • Bell, C.J.1    Hood, S.D.2    Nutt, D.J.3
  • 13
    • 33646104425 scopus 로고    scopus 로고
    • Lack of effects on core obsessive-compulsive symptoms of tryptophan depletion during symptom provocation in remitted obsessive-compulsive disorder patients
    • 10.1016/j.biopsych.2005.08.023 1:CAS:528:DC%2BD28XjsFOnt7k%3D 16213470
    • A Berney D Sookman M Leyton SN Young C Benkelfat 2006 Lack of effects on core obsessive-compulsive symptoms of tryptophan depletion during symptom provocation in remitted obsessive-compulsive disorder patients Biol Psychiatry 59 853 857 10.1016/j.biopsych.2005.08.023 1:CAS:528:DC%2BD28XjsFOnt7k%3D 16213470
    • (2006) Biol Psychiatry , vol.59 , pp. 853-857
    • Berney, A.1    Sookman, D.2    Leyton, M.3    Young, S.N.4    Benkelfat, C.5
  • 14
    • 84987469571 scopus 로고
    • The use of analogue scales in rating subjective feelings
    • AJ Bond MH Lader 1974 The use of analogue scales in rating subjective feelings Br J Med Psychology 47 211 218
    • (1974) Br J Med Psychology , vol.47 , pp. 211-218
    • Bond, A.J.1    Lader, M.H.2
  • 15
    • 40749132958 scopus 로고    scopus 로고
    • Acute tryptophan depletion does not alter central or plasma brain-derived neurotrophic factor in the rat
    • 10.1016/j.euroneuro.2007.07.006 1:CAS:528:DC%2BD1cXjtlWhsbk%3D 17719210
    • M Cahir TC Ardis JJ Elliott CB Kelly GP Reynolds SJ Cooper 2008 Acute tryptophan depletion does not alter central or plasma brain-derived neurotrophic factor in the rat Eur Neuropsychopharmacol 18 317 322 10.1016/j.euroneuro.2007. 07.006 1:CAS:528:DC%2BD1cXjtlWhsbk%3D 17719210
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 317-322
    • Cahir, M.1    Ardis, T.C.2    Elliott, J.J.3    Kelly, C.B.4    Reynolds, G.P.5    Cooper, S.J.6
  • 17
    • 67349265638 scopus 로고    scopus 로고
    • Serotonin and sensitivity to trauma-related exposure in selective serotonin reuptake inhibitors-recovered posttraumatic stress disorder
    • Corchs F, Nutt DJ, Hood S, Bernik M (2009) Serotonin and sensitivity to trauma-related exposure in selective serotonin reuptake inhibitors-recovered posttraumatic stress disorder. Biol Psychiatry 66:17-24
    • (2009) Biol Psychiatry , vol.66 , pp. 17-24
    • Corchs, F.1    Nutt, D.J.2    Hood, S.3    Bernik, M.4
  • 18
    • 49949120001 scopus 로고    scopus 로고
    • Plasma NPY concentrations during tryptophan and sham depletion in medication-free patients with remitted depression
    • 10.1016/j.jad.2008.01.014 1:CAS:528:DC%2BD1cXhtVKmtbrE 18281099
    • C Czermak R Hauger WC Drevets DA Luckenbaugh M Geraci DS Charney A Neumeister 2008 Plasma NPY concentrations during tryptophan and sham depletion in medication-free patients with remitted depression J Affect Disord 110 277 281 10.1016/j.jad.2008.01.014 1:CAS:528:DC%2BD1cXhtVKmtbrE 18281099
    • (2008) J Affect Disord , vol.110 , pp. 277-281
    • Czermak, C.1    Hauger, R.2    Drevets, W.C.3    Luckenbaugh, D.A.4    Geraci, M.5    Charney, D.S.6    Neumeister, A.7
  • 19
    • 33746890808 scopus 로고    scopus 로고
    • Depleting serotonin enhances both cardiovascular and psychological stress reactivity in recovered patients with anxiety disorders
    • 10.1097/01.jcp.0000227704.79740.c0 1:CAS:528:DC%2BD28XntFSmsro%3D 16855462
    • SJ Davies SD Hood SV Argyropoulos K Morris C Bell HJ Witchel PR Jackson DJ Nutt JP Potokar 2006 Depleting serotonin enhances both cardiovascular and psychological stress reactivity in recovered patients with anxiety disorders J Clin Psychopharmacol 26 414 418 10.1097/01.jcp.0000227704.79740.c0 1:CAS:528:DC%2BD28XntFSmsro%3D 16855462
    • (2006) J Clin Psychopharmacol , vol.26 , pp. 414-418
    • Davies, S.J.1    Hood, S.D.2    Argyropoulos, S.V.3    Morris, K.4    Bell, C.5    Witchel, H.J.6    Jackson, P.R.7    Nutt, D.J.8    Potokar, J.P.9
  • 20
    • 0033032825 scopus 로고    scopus 로고
    • Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: Implications for the role of serotonin in the mechanism of antidepressant action
    • 10.1016/S0006-3223(99)00014-1 1:CAS:528:DyaK1MXltFOlt7k%3D 10418696
    • PL Delgado HL Miller RM Salomon J Licinio JH Krystal FA Moreno GR Heninger DS Charney 1999 Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action Biol Psychiatry 46 212 220 10.1016/S0006-3223(99)00014-1 1:CAS:528:DyaK1MXltFOlt7k%3D 10418696
    • (1999) Biol Psychiatry , vol.46 , pp. 212-220
    • Delgado, P.L.1    Miller, H.L.2    Salomon, R.M.3    Licinio, J.4    Krystal, J.H.5    Moreno, F.A.6    Heninger, G.R.7    Charney, D.S.8
  • 21
    • 0018369087 scopus 로고
    • Diet-induced changes in plasma amino acid pattern: Effects on the brain uptake of large neutral amino acids, and on brain serotonin synthesis
    • Fernstrom JD (1979) Diet-induced changes in plasma amino acid pattern: effects on the brain uptake of large neutral amino acids, and on brain serotonin synthesis. J Neural Transm Suppl (15):55-67
    • (1979) J Neural Transm Suppl , Issue.15 , pp. 55-67
    • Fernstrom, J.D.1
  • 22
    • 53449096295 scopus 로고    scopus 로고
    • Serotonin and emotional processing: Does it help explain antidepressant drug action?
    • 10.1016/j.neuropharm.2008.06.036 1:CAS:528:DC%2BD1cXht1Knu7vP 18634807
    • CJ Harmer 2008 Serotonin and emotional processing: Does it help explain antidepressant drug action? Neuropharmacology 55 1023 1028 10.1016/j.neuropharm. 2008.06.036 1:CAS:528:DC%2BD1cXht1Knu7vP 18634807
    • (2008) Neuropharmacology , vol.55 , pp. 1023-1028
    • Harmer, C.J.1
  • 23
    • 42949163402 scopus 로고    scopus 로고
    • The nosologic relationship between generalized anxiety disorder and major depression
    • 10.1002/da.20491 18412057
    • JM Hettema 2008 The nosologic relationship between generalized anxiety disorder and major depression Depress Anxiety 25 300 316 10.1002/da.20491 18412057
    • (2008) Depress Anxiety , vol.25 , pp. 300-316
    • Hettema, J.M.1
  • 25
    • 27744486264 scopus 로고    scopus 로고
    • Acute tryptophan depletion. Part I: Rationale and methodology
    • 15996136
    • SD Hood CJ Bell DJ Nutt 2005 Acute tryptophan depletion. Part I: rationale and methodology Aust N Z J Psychiatry 39 558 564 15996136
    • (2005) Aust N Z J Psychiatry , vol.39 , pp. 558-564
    • Hood, S.D.1    Bell, C.J.2    Nutt, D.J.3
  • 26
    • 33749249169 scopus 로고    scopus 로고
    • Serotonin regulation of the human stress response
    • 10.1016/j.psyneuen.2006.07.001 1:CAS:528:DC%2BD28XhtVGiu7rI 16962720
    • SD Hood DA Hince H Robinson M Cirillo D Christmas JM Kaye 2006 Serotonin regulation of the human stress response Psychoneuroendocrinology 31 1087 1097 10.1016/j.psyneuen.2006.07.001 1:CAS:528:DC%2BD28XhtVGiu7rI 16962720
    • (2006) Psychoneuroendocrinology , vol.31 , pp. 1087-1097
    • Hood, S.D.1    Hince, D.A.2    Robinson, H.3    Cirillo, M.4    Christmas, D.5    Kaye, J.M.6
  • 27
    • 40349107245 scopus 로고    scopus 로고
    • Effects of tryptophan depletion on cognitive functioning, obsessive-compulsive symptoms and mood in obsessive-compulsive disorder: Preliminary results
    • 10.1159/000115778 18259085
    • AK Kulz S Meinzer M Kopasz U Voderholzer 2007 Effects of tryptophan depletion on cognitive functioning, obsessive-compulsive symptoms and mood in obsessive-compulsive disorder: preliminary results Neuropsychobiology 56 127 131 10.1159/000115778 18259085
    • (2007) Neuropsychobiology , vol.56 , pp. 127-131
    • Kulz, A.K.1    Meinzer, S.2    Kopasz, M.3    Voderholzer, U.4
  • 29
    • 0035085227 scopus 로고    scopus 로고
    • Venlafaxine occupation at the noradrenaline reuptake site: In-vivo determination in healthy volunteers
    • 10.1177/026988110101500102 1:CAS:528:DC%2BD3MXisFymu7g%3D 11277612
    • JK Melichar A Haida C Rhodes AH Reynolds DJ Nutt AL Malizia 2001 Venlafaxine occupation at the noradrenaline reuptake site: in-vivo determination in healthy volunteers J Psychopharmacol 15 9 12 10.1177/026988110101500102 1:CAS:528:DC%2BD3MXisFymu7g%3D 11277612
    • (2001) J Psychopharmacol , vol.15 , pp. 9-12
    • Melichar, J.K.1    Haida, A.2    Rhodes, C.3    Reynolds, A.H.4    Nutt, D.J.5    Malizia, A.L.6
  • 30
    • 42949126593 scopus 로고    scopus 로고
    • Is generalized anxiety disorder an anxiety or mood disorder? Considering multiple factors as we ponder the fate of GAD
    • 10.1002/da.20493 18412056
    • DS Mennin RG Heimberg DM Fresco MR Ritter 2008 Is generalized anxiety disorder an anxiety or mood disorder? Considering multiple factors as we ponder the fate of GAD Depress Anxiety 25 289 299 10.1002/da.20493 18412056
    • (2008) Depress Anxiety , vol.25 , pp. 289-299
    • Mennin, D.S.1    Heimberg, R.G.2    Fresco, D.M.3    Ritter, M.R.4
  • 32
    • 0031849045 scopus 로고    scopus 로고
    • Dose-dependent noradrenergic and serotonergic properties of venlafaxine in animal models indicative of antidepressant activity
    • 10.1007/s002130050638 1:CAS:528:DyaK1cXkvVKlurc%3D
    • JP Redrobe M Bourin MC Colombel GB Baker 1998 Dose-dependent noradrenergic and serotonergic properties of venlafaxine in animal models indicative of antidepressant activity Psychopharmacology (Berl) 138 1 8 10.1007/s002130050638 1:CAS:528:DyaK1cXkvVKlurc%3D
    • (1998) Psychopharmacology (Berl) , vol.138 , pp. 1-8
    • Redrobe, J.P.1    Bourin, M.2    Colombel, M.C.3    Baker, G.B.4
  • 33
    • 33947653784 scopus 로고    scopus 로고
    • Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: A meta-analysis of monoamine depletion studies
    • 10.1038/sj.mp.4001949 1:CAS:528:DC%2BD2sXjsV2isr8%3D 17389902
    • HG Ruhe NS Mason AH Schene 2007 Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies Mol Psychiatry 12 331 359 10.1038/sj.mp.4001949 1:CAS:528:DC%2BD2sXjsV2isr8%3D 17389902
    • (2007) Mol Psychiatry , vol.12 , pp. 331-359
    • Ruhe, H.G.1    Mason, N.S.2    Schene, A.H.3
  • 34
    • 0025131892 scopus 로고
    • Serotonin release varies with brain tryptophan levels
    • 10.1016/0006-8993(90)91761-5 1:CAS:528:DyaK3MXhsl2huw%3D%3D 1704290
    • JD Schaechter RJ Wurtman 1990 Serotonin release varies with brain tryptophan levels Brain Res 532 203 210 10.1016/0006-8993(90)91761-5 1:CAS:528:DyaK3MXhsl2huw%3D%3D 1704290
    • (1990) Brain Res , vol.532 , pp. 203-210
    • Schaechter, J.D.1    Wurtman, R.J.2
  • 35
    • 0034630244 scopus 로고    scopus 로고
    • Effects of tryptophan depletion on carbon dioxide provoked panic in panic disorder patients
    • 10.1016/S0165-1781(00)00117-7 1:CAS:528:DC%2BD3cXitlOlu7s%3D 10760376
    • K Schruers T Klaassen H Pols T Overbeek NE Deutz E Griez 2000 Effects of tryptophan depletion on carbon dioxide provoked panic in panic disorder patients Psychiatry Res 93 179 187 10.1016/S0165-1781(00)00117-7 1:CAS:528: DC%2BD3cXitlOlu7s%3D 10760376
    • (2000) Psychiatry Res , vol.93 , pp. 179-187
    • Schruers, K.1    Klaassen, T.2    Pols, H.3    Overbeek, T.4    Deutz, N.E.5    Griez, E.6
  • 36
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • 9881538
    • DV Sheehan Y Lecrubier KH Sheehan P Amorim J Janavs E Weiller T Hergueta R Baker GC Dunbar 1998 The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 J Clin Psychiatry 59 Suppl 20 22 33 9881538
    • (1998) J Clin Psychiatry , vol.59 , Issue.SUPPL 20 , pp. 22-33
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavs, J.5    Weiller, E.6    Hergueta, T.7    Baker, R.8    Dunbar, G.C.9
  • 37
    • 0031453608 scopus 로고    scopus 로고
    • Effects of citalopram treatment on behavioural, cardiovascular and neuroendocrine response to cholecystokinin tetrapeptide challenge in patients with panic disorder
    • 1:STN:280:DyaK1c%2FmsVGrsw%3D%3D 9401314
    • J Shlik A Aluoja V Vasar E Vasar T Podar J Bradwejn 1997 Effects of citalopram treatment on behavioural, cardiovascular and neuroendocrine response to cholecystokinin tetrapeptide challenge in patients with panic disorder J Psychiatry Neurosci 22 332 340 1:STN:280:DyaK1c%2FmsVGrsw%3D%3D 9401314
    • (1997) J Psychiatry Neurosci , vol.22 , pp. 332-340
    • Shlik, J.1    Aluoja, A.2    Vasar, V.3    Vasar, E.4    Podar, T.5    Bradwejn, J.6
  • 38
    • 0030611068 scopus 로고    scopus 로고
    • Relapse of depression after rapid depletion of tryptophan
    • 10.1016/S0140-6736(96)07044-4 1:STN:280:DyaK2s3kslWiuw%3D%3D 9093253
    • KA Smith CG Fairburn PJ Cowen 1997 Relapse of depression after rapid depletion of tryptophan Lancet 349 915 919 10.1016/S0140-6736(96)07044-4 1:STN:280:DyaK2s3kslWiuw%3D%3D 9093253
    • (1997) Lancet , vol.349 , pp. 915-919
    • Smith, K.A.1    Fairburn, C.G.2    Cowen, P.J.3
  • 40
    • 33646376901 scopus 로고    scopus 로고
    • Tryptophan depletion does not modify response to CCK-4 challenge in patients with panic disorder after treatment with citalopram
    • 10.1007/s00213-006-0351-1 1:CAS:528:DC%2BD28XjslGisbs%3D
    • I Toru J Shlik E Maron V Vasar DJ Nutt 2006 Tryptophan depletion does not modify response to CCK-4 challenge in patients with panic disorder after treatment with citalopram Psychopharmacology (Berl) 186 107 112 10.1007/s00213-006-0351-1 1:CAS:528:DC%2BD28XjslGisbs%3D
    • (2006) Psychopharmacology (Berl) , vol.186 , pp. 107-112
    • Toru, I.1    Shlik, J.2    Maron, E.3    Vasar, V.4    Nutt, D.J.5
  • 41
    • 0031043804 scopus 로고    scopus 로고
    • Effect of the selective serotonin reuptake inhibitor fluvoxamine on CCK-4 induced panic attacks
    • 10.1007/s002130050201
    • HJ van Megen HG Westenberg JA Den Boer B Slaap A Scheepmakers 1997 Effect of the selective serotonin reuptake inhibitor fluvoxamine on CCK-4 induced panic attacks Psychopharmacology (Berl) 129 357 364 10.1007/s002130050201
    • (1997) Psychopharmacology (Berl) , vol.129 , pp. 357-364
    • Van Megen, H.J.1    Westenberg, H.G.2    Den Boer, J.A.3    Slaap, B.4    Scheepmakers, A.5
  • 42
    • 0033036573 scopus 로고    scopus 로고
    • Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers
    • 10.1046/j.1471-4159.1999.721641.x 1:CAS:528:DyaK1MXitFCksbc%3D 10098872
    • WA Williams SE Shoaf D Hommer R Rawlings M Linnoila 1999 Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers J Neurochem 72 1641 1647 10.1046/j.1471-4159.1999.721641.x 1:CAS:528:DyaK1MXitFCksbc%3D 10098872
    • (1999) J Neurochem , vol.72 , pp. 1641-1647
    • Williams, W.A.1    Shoaf, S.E.2    Hommer, D.3    Rawlings, R.4    Linnoila, M.5
  • 44
    • 0037214154 scopus 로고    scopus 로고
    • Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios
    • 1:CAS:528:DC%2BD3sXhtFyntg%3D%3D 12499331
    • RJ Wurtman JJ Wurtman MM Regan JM McDermott RH Tsay JJ Breu 2003 Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios Am J Clin Nutr 77 128 132 1:CAS:528:DC%2BD3sXhtFyntg%3D%3D 12499331
    • (2003) Am J Clin Nutr , vol.77 , pp. 128-132
    • Wurtman, R.J.1    Wurtman, J.J.2    Regan, M.M.3    McDermott, J.M.4    Tsay, R.H.5    Breu, J.J.6
  • 45
    • 0022182551 scopus 로고
    • Tryptophan depletion causes a rapid lowering of mood in normal males
    • 10.1007/BF00431803 1:CAS:528:DyaL2MXlsFyhtr8%3D
    • SN Young SE Smith RO Pihl FR Ervin 1985 Tryptophan depletion causes a rapid lowering of mood in normal males Psychopharmacology (Berl) 87 173 177 10.1007/BF00431803 1:CAS:528:DyaL2MXlsFyhtr8%3D
    • (1985) Psychopharmacology (Berl) , vol.87 , pp. 173-177
    • Young, S.N.1    Smith, S.E.2    Pihl, R.O.3    Ervin, F.R.4


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