Recognition and management of acute medication poisoning

American Family Physician

Volumn 81, Issue 3, 2010, Pages 316-323

  Frithsen, Ivar L ^a,b   Simpson Jr , William M ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ACTIVATED CARBON; ADRENALIN; ATROPINE; BENZODIAZEPINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BICARBONATE; CALCIUM CHANNEL BLOCKING AGENT; CLONIDINE; DOPAMINE; FLUMAZENIL; GLUCAGON; GLUCONATE CALCIUM; GLUCOSE; INSULIN; IPECAC; LAXATIVE; NALOXONE; NORADRENALIN; OCTREOTIDE; OPIATE; PARACETAMOL; SALICYLIC ACID; SULFONYLUREA; TRICYCLIC ANTIDEPRESSANT AGENT; PRESCRIPTION DRUG;

ACIDEMIA; ACIDOSIS; ACUTE TOXICITY; ANTICHOLINERGIC EFFECT; APNEA; ARTICLE; BEHAVIOR CHANGE; CHILD; CYANOSIS; DRUG CONTRAINDICATION; DRUG DOSE TITRATION; DRUG INDICATION; DRUG INTOXICATION; ELECTROLYTE DISTURBANCE; EMERGENCY CARE; EMERGENCY HEALTH SERVICE; EMERGENCY WARD; FATALITY; FLUID RESUSCITATION; GENERAL PRACTITIONER; HEMODIALYSIS; HOME CARE; HUMAN; HYPERTHERMIA; HYPOTENSION; HYPOTHERMIA; HYPOXIA; KIDNEY FUNCTION; LABORATORY TEST; LETHARGY; LIVER FUNCTION; LOADING DRUG DOSE; MENTAL DISEASE; MENTAL HEALTH; OPIATE ADDICTION; PALLIATIVE THERAPY; PATIENT POSITIONING; PHYSICAL DISEASE BY BODY FUNCTION; POISON CENTER; PULSE OXIMETRY; RESPIRATORY DISTRESS; STOMACH LAVAGE; TELECONSULTATION; TRANSDERMAL PATCH; VITAL SIGN; ADULT; DRUG TOXICITY; HOSPITALIZATION; REVIEW; UNITED STATES;

ADULT; CHILD; DRUG TOXICITY; HOSPITALIZATION; HUMANS; PRESCRIPTION DRUGS; TRIAGE; UNITED STATES;

EID: 77449124482     PISSN: 0002838X     EISSN: 0002838X     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Bronstein AC, Spyker DA, Cantilena LR Jr, Green J, Rumack BH, Heard SE. 2006 annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS). Clin Toxicol (Phila). 2007;45(8):815-917.
2. Institute of Medicine (U.S.) Committee on Poison Prevention and Control. Forging a Poison Prevention and Control System. Washington, DC: National Academies Press; 2004.
3. Rice DP, Mackenzie EJ. Cost of Injury in the United States: A Report to Congress, 1989. San Francisco, Calif.: Institute for Health and Aging, University of California, San Francisco; 1989.
4. Henry K, Harris CR. Deadly ingestions. Pediatr Clin North Am. 2006;53(2):293-315.
5. Ford MD. Clinical Toxicology. Philadelphia, Pa.: Saunders; 2001.
6. Erickson TB, Thompson TM, Lu JJ. The approach to the patient with an unknown overdose. Emerg Med Clin North Am. 2007;25(2):249-281.
7. Killian CA, Roberge RJ, Krenzelok EP, Stonage CL. "Cloniderm" toxicity: another manifestation of clonidine overdose. Pediatr Emerg Care. 1997;13(5):340-341.
8. Chyka PA, Seger D, Krenzelok EP, et al., for the American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinical Toxicologists. Position paper: single-dose activated charcoal. Clin Toxicol (Phila). 2005;43(2):61-87.
9. Vale JA, Kulig K, for the American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinical Toxicologists. Position paper: gastric lavage. J Toxicol Clin Toxicol. 2004;42(7):933-943.
10. Position paper: cathartics [published correction appears in J Toxicol Clin Toxicol. 2004;42(7):1000]. J Toxicol Clin Toxicol. 2004;42(3):243-253.
11. Position paper: whole bowel irrigation [published correction appears in J Toxicol Clin Toxicol. 2004;42(7):1000]. J Toxicol Clin Toxicol. 2004;42(6):843-854.
12. Bateman DN. Gastric decontamination-a view for the millennium. J Accid Emerg Med. 1999;16(2):84-86.
13. American Academy of Pediatrics Committee on Injury, Violence, and Poison Prevention. Poison treatment in the home. Pediatrics. 2003;112(5):1182-1185.
14. Position paper: ipecac syrup [published correction appears in J Toxicol Clin Toxicol. 2004;42(7):1000]. J Toxicol Clin Toxicol. 2004;42(2):133-143.
15. Mannoguerra AS, Cobaugh DJ, for the Guidelines for the Management of Poisoning Consensus Panel. Guideline on the use of ipecac syrup in the out-of-hospital management of ingested poisons. Clin Toxicol (Phila). 2005; 43(1):1-10.
16. Silber TJ. Ipecac syrup abuse, morbidity, and mortality: isn't it time to repeal its over-the-counter status? J Adolesc Health. 2005;37(3):256-260.
17. Rowden AK, Norvell J, Eldridge DL, Kirk MA. Acetaminophen poisoning. Clin Lab Med. 2006;26(1):49-65.
18. White ML, Liebelt EL. Update on antidotes for pediatric poisoning. Pediatr Emerg Care. 2006;22(11):740-746.
19. Sung L, Simons JA, Dayneka NL. Dilution of intravenous N-acetylcysteine as a cause of hyponatremia. Pediatrics. 1997;100(3 pt 1):389-391.
20. Heard KJ. Acetylcysteine for acetaminophen poisoning. N Engl J Med. 2008;359(3):285-292.
21. Kerns W 2nd. Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007;25(2):309-331.
22. Anderson AC. Management of beta-adrenergic blocker poisoning. Clin Pediatr Emerg Med. 2008;9(1):4-16.
23. Anderson A. Calcium-channel blocker overdose. Clin Pediatr Emerg Med. 2005;6(2):109-115.
24. Seger DL. Clonidine toxicity revisited. J Toxicol Clin Toxicol. 2002;40(2):145-155.
25. Lheureux PE, Zahir S, Penaloza A, Gris M. Bench-tobedside review: antidotal treatment of sulfonylureainduced hypoglycaemia with octreotide. Crit Care. 2005;9(6):543-549.
26. Harrigan RA, Nathan MS, Beattie P. Oral agents for the treatment of type 2 diabetes mellitus: pharmacology, toxicity, and treatment. Ann Emerg Med. 2001; 38(1):68-78.
27. Rath S, Bar-Zeev N, Anderson K, Fahy R, Roseby R. Octreotide in children with hypoglycaemia due to sulfonylurea ingestion. J Paediatr Child Health. 2008; 44(6):383-384.
28. Porter RS, ed. The Merck Manual of Diagnosis and Therapy. 18th ed. Whitehouse Station, N.J.: Merck & Co., Inc.; 2006. http://www.merck.com/ mmpe. Accessed July 14, 2009.
29. Rosenbaum TG, Kou M. Are one or two dangerous? Tricyclic antidepressant exposure in toddlers. J Emerg Med. 2005;28(2):169-174.
30. Little GL, Boniface KS. Are one or two dangerous? Sulfonylurea exposure in toddlers. J Emerg Med. 2005; 28(3):305-310.
31. McGregor T, Parkar M, Rao S. Evaluation and management of common childhood poisonings. Am Fam Physician. 2009;79(5):397-403.