메뉴 건너뛰기




Volumn 51, Issue 2, 2010, Pages 1181-1189

Generation of light-sensitive photoreceptor phenotypes by genetic modification of human adult ocular stem cells with Crx

Author keywords

[No Author keywords available]

Indexed keywords

BETA 6 PHOSPHODIESTERASE; BETA TUBULIN; BETA TUBULIN III; BLUE CONE OPSIN; CONE OPSIN; CYCLIC GMP; CYCLIC NUCLEOTIDE GATED CATION CHANNEL 3; CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLINE; MICROTUBULE ASSOCIATED PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN 2A; MICROTUBULE ASSOCIATED PROTEIN 2B; NESTIN; NEUROFILAMENT PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHODIESTERASE; RHODOPSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CRX; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CONE ROD HOMEOBOX PROTEIN; HOMEODOMAIN PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 77449101402     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4385     Document Type: Article
Times cited : (19)

References (62)
  • 1
    • 0033854406 scopus 로고    scopus 로고
    • Retinal stem cells in vertebrates
    • Perron M, Harris WA. Retinal stem cells in vertebrates. Bioessays. 2000;22(8):685-688.
    • (2000) Bioessays , vol.22 , Issue.8 , pp. 685-688
    • Perron, M.1    Harris, W.A.2
  • 2
    • 11044239127 scopus 로고    scopus 로고
    • Retinal stem cells and regeneration
    • Moshiri A, Close J, Reh TA. Retinal stem cells and regeneration. Int J Dev Biol. 2004;48(8-9):1003-1014.
    • (2004) Int J Dev Biol , vol.48 , Issue.8-9 , pp. 1003-1014
    • Moshiri, A.1    Close, J.2    Reh, T.A.3
  • 3
    • 0034677891 scopus 로고    scopus 로고
    • Retinal stem cells in the adult mammalian eye
    • Tropepe V, Coles BL, Chiasson BJ, et al. Retinal stem cells in the adult mammalian eye. Science. 2000;287(5460):2032-2036.
    • (2000) Science , vol.287 , Issue.5460 , pp. 2032-2036
    • Tropepe, V.1    Coles, B.L.2    Chiasson, B.J.3
  • 4
    • 0034643271 scopus 로고    scopus 로고
    • Identification of neural progenitors in the adult mammalian eye
    • Ahmad I, Tang L, Pham H. Identification of neural progenitors in the adult mammalian eye. Biochem Biophys Res Commun. 2000;270(2):517-521.
    • (2000) Biochem Biophys Res Commun , vol.270 , Issue.2 , pp. 517-521
    • Ahmad, I.1    Tang, L.2    Pham, H.3
  • 5
    • 0034656054 scopus 로고    scopus 로고
    • Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens
    • Fischer AJ, Reh TA. Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens. Dev Biol. 2000;220(2):197-210.
    • (2000) Dev Biol , vol.220 , Issue.2 , pp. 197-210
    • Fischer, A.J.1    Reh, T.A.2
  • 6
    • 8144224971 scopus 로고    scopus 로고
    • Facile isolation and the characterization of human retinal stem cells
    • Coles BL, Angenieux B, Inoue T, et al. Facile isolation and the characterization of human retinal stem cells. Proc Natl Acad Sci USA. 2004;101(44):15772-15777.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.44 , pp. 15772-15777
    • Coles, B.L.1    Angenieux, B.2    Inoue, T.3
  • 7
    • 34250653225 scopus 로고    scopus 로고
    • Stem cells: A source for neuron repair in retinal disease
    • Wallace VA. Stem cells: a source for neuron repair in retinal disease. Can J Ophthalmol. 2007;42(3):442-446.
    • (2007) Can J Ophthalmol , vol.42 , Issue.3 , pp. 442-446
    • Wallace, V.A.1
  • 8
    • 41649112407 scopus 로고    scopus 로고
    • Neuronal stem/progenitor cells in the vertebrate eye
    • Ohta K, Ito A, Tanaka H. Neuronal stem/progenitor cells in the vertebrate eye. Dev Growth Differ. 2008;50(4):253-259.
    • (2008) Dev Growth Differ , vol.50 , Issue.4 , pp. 253-259
    • Ohta, K.1    Ito, A.2    Tanaka, H.3
  • 9
    • 36248940285 scopus 로고    scopus 로고
    • Towards therapeutic application of ocular stem cells
    • Pellegrini G, De Luca M, Arsenijevic Y. Towards therapeutic application of ocular stem cells. Semin Cell Dev Biol. 2007;18(6):805-818.
    • (2007) Semin Cell Dev Biol , vol.18 , Issue.6 , pp. 805-818
    • Pellegrini, G.1    De Luca, M.2    Arsenijevic, Y.3
  • 10
    • 0032830443 scopus 로고    scopus 로고
    • Photoreceptor layer reconstruction in a rodent model of retinal degeneration
    • Kwan AS, Wang S, Lund RD. Photoreceptor layer reconstruction in a rodent model of retinal degeneration. Exp Neurol. 1999;159(1):21-33.
    • (1999) Exp Neurol , vol.159 , Issue.1 , pp. 21-33
    • Kwan, A.S.1    Wang, S.2    Lund, R.D.3
  • 11
    • 4043118342 scopus 로고    scopus 로고
    • Progress in retinal sheet transplantation
    • Aramant RB, Seiler MJ. Progress in retinal sheet transplantation. Prog Retin Eye Res. 2004;23(5):475-494.
    • (2004) Prog Retin Eye Res , vol.23 , Issue.5 , pp. 475-494
    • Aramant, R.B.1    Seiler, M.J.2
  • 12
    • 0037377975 scopus 로고    scopus 로고
    • Retinal transplantation-induced recovery of retinotectal visual function in a rodent model of retinitis pigmentosa
    • Sagdullaev BT, Aramant RB, Seiler MJ, Woch G, McCall MA. Retinal transplantation-induced recovery of retinotectal visual function in a rodent model of retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2003;44(4):1686-1695.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.4 , pp. 1686-1695
    • Sagdullaev, B.T.1    Aramant, R.B.2    Seiler, M.J.3    Woch, G.4    McCall, M.A.5
  • 13
    • 0032919846 scopus 로고    scopus 로고
    • Photoreceptor function of retinal transplants implicated by light-dark shift of S-antigen and rod transducin
    • Seiler MJ, Aramant RB, Ball SL. Photoreceptor function of retinal transplants implicated by light-dark shift of S-antigen and rod transducin. Vision Res. 1999;39(15):2589-2596.
    • (1999) Vision Res , vol.39 , Issue.15 , pp. 2589-2596
    • Seiler, M.J.1    Aramant, R.B.2    Ball, S.L.3
  • 14
    • 17444382319 scopus 로고    scopus 로고
    • Transplantation of neuroblastic progenitor cells as a sheet preserves and restores retinal function
    • Seiler MJ, Aramant RB. Transplantation of neuroblastic progenitor cells as a sheet preserves and restores retinal function. Semin Ophthalmol. 2005;20(1):31-42.
    • (2005) Semin Ophthalmol , vol.20 , Issue.1 , pp. 31-42
    • Seiler, M.J.1    Aramant, R.B.2
  • 15
    • 33750861299 scopus 로고    scopus 로고
    • Retinal repair by transplantation of photoreceptor precursors
    • MacLaren RE, Pearson RA, MacNeil A, et al. Retinal repair by transplantation of photoreceptor precursors. Nature. 2006;444(7116):203-207.
    • (2006) Nature , vol.444 , Issue.7116 , pp. 203-207
    • McLaren, R.E.1    Pearson, R.A.2    McNeil, A.3
  • 18
    • 0037382378 scopus 로고    scopus 로고
    • Transplantation of ocular stem cells: The role of injury in incorporation and differentiation of grafted cells in the retina
    • Chacko DM, Das AV, Zhao X, James J, Bhattacharya S, Ahmad I. Transplantation of ocular stem cells: the role of injury in incorporation and differentiation of grafted cells in the retina. Vision Res. 2003;43(8):937-946.
    • (2003) Vision Res , vol.43 , Issue.8 , pp. 937-946
    • Chacko, D.M.1    Das, A.V.2    Zhao, X.3    James, J.4    Bhattacharya, S.5    Ahmad, I.6
  • 19
    • 39549112774 scopus 로고    scopus 로고
    • Induction of functional photoreceptor phenotype by exogenous Crx expression in mouse retinal stem cells
    • Jomary C, Jones SE. Induction of functional photoreceptor phenotype by exogenous Crx expression in mouse retinal stem cells. Invest Ophthalmol Vis Sci. 2008;49(1):429-437.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.1 , pp. 429-437
    • Jomary, C.1    Jones, S.E.2
  • 20
    • 0034677891 scopus 로고    scopus 로고
    • Retinal stem cells in the adult mammalian eye
    • Tropepe V, Coles BL, Chiasson BJ, et al. Retinal stem cells in the adult mammalian eye. Science. 2000;287(5460):2032.
    • (2000) Science , vol.287 , Issue.5460 , pp. 2032
    • Tropepe, V.1    Coles, B.L.2    Chiasson, B.J.3
  • 21
    • 0034643271 scopus 로고    scopus 로고
    • Identification of neural progenitors in the adult mammalian eye
    • Ahmad I, Tang L, Pham H. Identification of neural progenitors in the adult mammalian eye. Biochem Biophys Res Commun. 2000;270(2):517-521.
    • (2000) Biochem Biophys Res Commun , vol.270 , Issue.2 , pp. 517-521
    • Ahmad, I.1    Tang, L.2    Pham, H.3
  • 22
    • 0036402525 scopus 로고    scopus 로고
    • Adult corneal limbal epithelium: A model for studying neural potential of non-neural stem cells/progenitors
    • Zhao X, Das AV, Thoreson WB, et al. Adult corneal limbal epithelium: a model for studying neural potential of non-neural stem cells/progenitors. Dev Biol. 2002;250(2):317-331.
    • (2002) Dev Biol , vol.250 , Issue.2 , pp. 317-331
    • Zhao, X.1    Das, A.V.2    Thoreson, W.B.3
  • 23
    • 0033549257 scopus 로고    scopus 로고
    • In vitro analysis of a mammalian retinal progenitor that gives rise to neurons and glia
    • Ahmad I, Dooley CM, Thoreson WB, Rogers JA, Afiat S. In vitro analysis of a mammalian retinal progenitor that gives rise to neurons and glia. Brain Res. 1999;831(1-2):1-10.
    • (1999) Brain Res , vol.831 , Issue.1-2 , pp. 1-10
    • Ahmad, I.1    Dooley, C.M.2    Thoreson, W.B.3    Rogers, J.A.4    Afiat, S.5
  • 24
    • 0027442205 scopus 로고
    • Abnormal distribution of retinal clusterin in retinitis pigmentosa
    • Jomary C, Murphy BF, Neal MJ, Jones SE. Abnormal distribution of retinal clusterin in retinitis pigmentosa. Mol Brain Res. 1993;20(3):274-278.
    • (1993) Mol Brain Res , vol.20 , Issue.3 , pp. 274-278
    • Jomary, C.1    Murphy, B.F.2    Neal, M.J.3    Jones, S.E.4
  • 25
    • 0037223362 scopus 로고    scopus 로고
    • Regulation of RelA (p65) function by the large subunit of replication factor C
    • Anderson LA, Perkins ND. Regulation of RelA (p65) function by the large subunit of replication factor C. Mol Cell Biol. 2003;23(2):721-732.
    • (2003) Mol Cell Biol , vol.23 , Issue.2 , pp. 721-732
    • Anderson, L.A.1    Perkins, N.D.2
  • 26
    • 27244450331 scopus 로고    scopus 로고
    • Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes
    • Akagi T, Akita J, Haruta M, et al. Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes. Invest Ophthalmol Vis Sci. 2005;46(9):3411-3419.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.9 , pp. 3411-3419
    • Akagi, T.1    Akita, J.2    Haruta, M.3
  • 27
    • 0034701747 scopus 로고    scopus 로고
    • Cloning and immunocytochemical localization of a cyclic nucleotide-gated channel alpha-subunit to all cone photoreceptors in the mouse retina
    • Hirano AA, Hack I, Wassle H, Duvoisin RM. Cloning and immunocytochemical localization of a cyclic nucleotide-gated channel alpha-subunit to all cone photoreceptors in the mouse retina. J Comp Neurol. 2000;421(1):80-94.
    • (2000) J Comp Neurol , vol.421 , Issue.1 , pp. 80-94
    • Hirano, A.A.1    Hack, I.2    Wassle, H.3    Duvoisin, R.M.4
  • 28
    • 13844280894 scopus 로고    scopus 로고
    • Oct4 expression in adult human stem cells: Evidence in support of the stem cell theory of carcinogenesis
    • Tai MH, Chang CC, Kiupel M, Webster JD, Olson LK, Trosko JE. Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis. 2005;26(2):495-502.
    • (2005) Carcinogenesis , vol.26 , Issue.2 , pp. 495-502
    • Tai, M.H.1    Chang, C.C.2    Kiupel, M.3    Webster, J.D.4    Olson, L.K.5    Trosko, J.E.6
  • 29
    • 54449097120 scopus 로고    scopus 로고
    • Human neural crest cells display molecular and phenotypic hallmarks of stem cells
    • Thomas S, Thomas M, Wincker P, et al. Human neural crest cells display molecular and phenotypic hallmarks of stem cells. Hum Mol Genet. 2008;17(21):3411-3425.
    • (2008) Hum Mol Genet , vol.17 , Issue.21 , pp. 3411-3425
    • Thomas, S.1    Thomas, M.2    Wincker, P.3
  • 30
    • 33749455736 scopus 로고    scopus 로고
    • IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme
    • Balenci L, Clarke ID, Dirks PB, et al. IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme. Cancer Res. 2006;66(18):9074-9082.
    • (2006) Cancer Res , vol.66 , Issue.18 , pp. 9074-9082
    • Balenci, L.1    Clarke, I.D.2    Dirks, P.B.3
  • 31
    • 12144266963 scopus 로고    scopus 로고
    • Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex
    • Englund C, Fink A, Lau C, et al. Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci. 2005;25(1):247-251.
    • (2005) J Neurosci , vol.25 , Issue.1 , pp. 247-251
    • Englund, C.1    Fink, A.2    Lau, C.3
  • 32
    • 0035968313 scopus 로고    scopus 로고
    • A novel human striated muscle RING zinc finger protein, SMRZ, interacts with SMT3b via its RING domain
    • Dai KS, Liew CC. A novel human striated muscle RING zinc finger protein, SMRZ, interacts with SMT3b via its RING domain. J Biol Chem. 2001;276(26):23992-23999.
    • (2001) J Biol Chem , vol.276 , Issue.26 , pp. 23992-23999
    • Dai, K.S.1    Liew, C.C.2
  • 33
    • 33746585709 scopus 로고    scopus 로고
    • Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta
    • Srinivas M, Ng L, Liu H, Jia L, Forrest D. Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta. Mol Endocrinol. 2006;20(8):1728-1741.
    • (2006) Mol Endocrinol , vol.20 , Issue.8 , pp. 1728-1741
    • Srinivas, M.1    Ng, L.2    Liu, H.3    Jia, L.4    Forrest, D.5
  • 34
    • 0030759730 scopus 로고    scopus 로고
    • Rescue of photoreceptor function by AAV-mediated gene transfer in a mouse model of inherited retinal degeneration
    • Jomary C, Vincent KA, Grist J, Neal MJ, Jones SE. Rescue of photoreceptor function by AAV-mediated gene transfer in a mouse model of inherited retinal degeneration. Gene Ther. 1997;4(7):683-690.
    • (1997) Gene Ther , vol.4 , Issue.7 , pp. 683-690
    • Jomary, C.1    Vincent, K.A.2    Grist, J.3    Neal, M.J.4    Jones, S.E.5
  • 35
    • 0033535350 scopus 로고    scopus 로고
    • Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
    • Desagher S, Osen-Sand A, Nichols A, et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol. 1999;144(5):891-901.
    • (1999) J Cell Biol , vol.144 , Issue.5 , pp. 891-901
    • Desagher, S.1    Osen-Sand, A.2    Nichols, A.3
  • 36
    • 9444251786 scopus 로고    scopus 로고
    • Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue
    • Akagi T, Mandai M, Ooto S, et al. Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue. Invest Ophthalmol Vis Sci. 2004;45(12):4570-4575.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.12 , pp. 4570-4575
    • Akagi, T.1    Mandai, M.2    Ooto, S.3
  • 37
    • 0035845485 scopus 로고    scopus 로고
    • Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase
    • Furge KA, Kiewlich D, Le P, et al. Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase. Proc Natl Acad Sci USA. 2001;98(19):10722-10727.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.19 , pp. 10722-10727
    • Furge, K.A.1    Kiewlich, D.2    Le, P.3
  • 38
    • 33746585709 scopus 로고    scopus 로고
    • Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta
    • Srinivas M, Ng L, Liu H, Jia L, Forrest D. Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta. Mol Endocrinol. 2006;20(8):1728-1741.
    • (2006) Mol Endocrinol , vol.20 , Issue.8 , pp. 1728-1741
    • Srinivas, M.1    Ng, L.2    Liu, H.3    Jia, L.4    Forrest, D.5
  • 40
    • 0030937808 scopus 로고    scopus 로고
    • Vertebrate embryonic cells will become nerve cells unless told otherwise
    • Hemmati-Brivanlou A, Melton D. Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell. 1997;88(1):13-17.
    • (1997) Cell , vol.88 , Issue.1 , pp. 13-17
    • Hemmati-Brivanlou, A.1    Melton, D.2
  • 41
    • 33748617592 scopus 로고    scopus 로고
    • Isolation of neural stem cells from the spinal cords of low temperature preserved abortuses
    • Liu X, Zhu Y, Gao W. Isolation of neural stem cells from the spinal cords of low temperature preserved abortuses. J Neurosci Methods. 2006;157(1):64-70.
    • (2006) J Neurosci Methods , vol.157 , Issue.1 , pp. 64-70
    • Liu, X.1    Zhu, Y.2    Gao, W.3
  • 42
    • 0032957230 scopus 로고    scopus 로고
    • Multipotent neurospheres can be derived from forebrain subependymal zone and spinal cord of adult mice after protracted postmortem intervals
    • Laywell ED, Kukekov VG, Steindler DA. Multipotent neurospheres can be derived from forebrain subependymal zone and spinal cord of adult mice after protracted postmortem intervals. Exp Neurol. 1999;156(2):430-433.
    • (1999) Exp Neurol , vol.156 , Issue.2 , pp. 430-433
    • Laywell, E.D.1    Kukekov, V.G.2    Steindler, D.A.3
  • 43
    • 0242362288 scopus 로고    scopus 로고
    • Isolation of neural stem cells from the forebrain of deceased early postnatal and adult rats with protracted post-mortem intervals
    • Xu Y, Kimura K, Matsumoto N, Ide C. Isolation of neural stem cells from the forebrain of deceased early postnatal and adult rats with protracted post-mortem intervals. J Neurosci Res. 2003;74(4):533-540.
    • (2003) J Neurosci Res , vol.74 , Issue.4 , pp. 533-540
    • Xu, Y.1    Kimura, K.2    Matsumoto, N.3    Ide, C.4
  • 44
    • 34548301272 scopus 로고    scopus 로고
    • The effect of postmortem time, donor age and sex on the generation of neurospheres from adult human retina
    • Carter DA, Mayer EJ, Dick AD. The effect of postmortem time, donor age and sex on the generation of neurospheres from adult human retina. Br J Ophthalmol. 2007;91(9):1216-1218.
    • (2007) Br J Ophthalmol , vol.91 , Issue.9 , pp. 1216-1218
    • Carter, D.A.1    Mayer, E.J.2    Dick, A.D.3
  • 45
    • 8144224971 scopus 로고    scopus 로고
    • Facile isolation and the characterization of human retinal stem cells
    • Coles BL, Angenieux B, Inoue T, et al. Facile isolation and the characterization of human retinal stem cells. Proc Natl Acad Sci USA. 2004;101(44):15772-15777.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.44 , pp. 15772-15777
    • Coles, B.L.1    Angenieux, B.2    Inoue, T.3
  • 46
    • 0030669568 scopus 로고    scopus 로고
    • Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor
    • Freund CL, Gregory-Evans CY, Furukawa T, et al. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell. 1997;91(4):543-553.
    • (1997) Cell , vol.91 , Issue.4 , pp. 543-553
    • Freund, C.L.1    Gregory-Evans, C.Y.2    Furukawa, T.3
  • 47
    • 0031447030 scopus 로고    scopus 로고
    • Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration
    • Swain PK, Chen S, Wang QL, et al. Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration. Neuron. 1997;19(6):1329-1336.
    • (1997) Neuron , vol.19 , Issue.6 , pp. 1329-1336
    • Swain, P.K.1    Chen, S.2    Wang, Q.L.3
  • 48
    • 0030781996 scopus 로고    scopus 로고
    • Crx, a novel Otx-like pairedhomeodomain protein, binds to and transactivates photoreceptor cell-specific genes
    • Chen S, Wang QL, Nie Z, et al. Crx, a novel Otx-like pairedhomeodomain protein, binds to and transactivates photoreceptor cell-specific genes. Neuron. 1997;19(5):1017-1030.
    • (1997) Neuron , vol.19 , Issue.5 , pp. 1017-1030
    • Chen, S.1    Wang, Q.L.2    Nie, Z.3
  • 49
    • 0030725687 scopus 로고    scopus 로고
    • Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation
    • Furukawa T, Morrow EM, Cepko CL. Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell. 1997;91(4):531-541.
    • (1997) Cell , vol.91 , Issue.4 , pp. 531-541
    • Furukawa, T.1    Morrow, E.M.2    Cepko, C.L.3
  • 50
    • 0035878559 scopus 로고    scopus 로고
    • Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development
    • Bibb LC, Holt JK, Tarttelin EE, et al. Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development. Hum Mol Genet. 2001;10(15):1571-1579.
    • (2001) Hum Mol Genet , vol.10 , Issue.15 , pp. 1571-1579
    • Bibb, L.C.1    Holt, J.K.2    Tarttelin, E.E.3
  • 51
    • 14544284571 scopus 로고    scopus 로고
    • Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type
    • Philips GT, Stair CN, Young Lee H, et al. Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type. Dev Biol. 2005;279(2):308-321.
    • (2005) Dev Biol , vol.279 , Issue.2 , pp. 308-321
    • Philips, G.T.1    Stair, C.N.2    Young Lee, H.3
  • 52
    • 34249282694 scopus 로고    scopus 로고
    • Alterations of rx1 and pax6 expression levels at neural plate stages differentially affect the production of retinal cell types and maintenance of retinal stem cell qualities
    • Zaghloul NA, Moody SA. Alterations of rx1 and pax6 expression levels at neural plate stages differentially affect the production of retinal cell types and maintenance of retinal stem cell qualities. Dev Biol. 2007;306(1):222-240.
    • (2007) Dev Biol , vol.306 , Issue.1 , pp. 222-240
    • Zaghloul, N.A.1    Moody, S.A.2
  • 53
    • 34047160933 scopus 로고    scopus 로고
    • The proliferation and expansion of retinal stem cells require functional Pax6
    • Xu S, Sunderland ME, Coles BL, et al. The proliferation and expansion of retinal stem cells require functional Pax6. Dev Biol. 2007;304(2):713-721.
    • (2007) Dev Biol , vol.304 , Issue.2 , pp. 713-721
    • Xu, S.1    Sunderland, M.E.2    Coles, B.L.3
  • 54
    • 0034656054 scopus 로고    scopus 로고
    • Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens
    • Fischer AJ, Reh TA. Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens. Dev Biol. 2000;220(2):197-210.
    • (2000) Dev Biol , vol.220 , Issue.2 , pp. 197-210
    • Fischer, A.J.1    Reh, T.A.2
  • 55
    • 0025352402 scopus 로고
    • A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
    • Rosner MH, Vigano MA, Ozato K, et al. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature. 1990;345(6277):686-692.
    • (1990) Nature , vol.345 , Issue.6277 , pp. 686-692
    • Rosner, M.H.1    Vigano, M.A.2    Ozato, K.3
  • 56
    • 0025291459 scopus 로고
    • Oct-4: A germline-specific transcription factor mapping to the mouse t-complex
    • Scholer HR, Dressler GR, Balling R, Rohdewohld H, Gruss P. Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J. 1990;9(7):2185-2195.
    • (1990) EMBO J , vol.9 , Issue.7 , pp. 2185-2195
    • Scholer, H.R.1    Dressler, G.R.2    Balling, R.3    Rohdewohld, H.4    Gruss, P.5
  • 57
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet. 2000;24(4):372-376.
    • (2000) Nat Genet , vol.24 , Issue.4 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 58
    • 0034704768 scopus 로고    scopus 로고
    • Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx
    • Livesey FJ, Furukawa T, Steffen MA, Church GM, Cepko CL. Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx. Curr Biol. 2000;10(6):301-310.
    • (2000) Curr Biol , vol.10 , Issue.6 , pp. 301-310
    • Livesey, F.J.1    Furukawa, T.2    Steffen, M.A.3    Church, G.M.4    Cepko, C.L.5
  • 59
    • 38849100921 scopus 로고    scopus 로고
    • Regulation of photoreceptor gene expression by Crx-associated transcription factor network
    • Hennig AK, Peng GH, Chen S. Regulation of photoreceptor gene expression by Crx-associated transcription factor network. Brain Res. 2008;1192:114-133.
    • (2008) Brain Res , vol.1192 , pp. 114-133
    • Hennig, A.K.1    Peng, G.H.2    Chen, S.3
  • 60
    • 1542742250 scopus 로고    scopus 로고
    • Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice
    • Tan E, Ding XQ, Saadi A, Agarwal N, Naash MI, Al-Ubaidi MR. Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice. Invest Ophthalmol Vis Sci. 2004;45(3):764-768.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.3 , pp. 764-768
    • Tan, E.1    Ding, X.Q.2    Saadi, A.3    Agarwal, N.4    Naash, M.I.5    Al-Ubaidi, M.R.6
  • 61
    • 0029803998 scopus 로고    scopus 로고
    • Photoreceptor repair in response to RPE transplants in RCS rats: Outer segment regeneration
    • Lin N, Fan W, Sheedlo HJ, Aschenbrenner JE, Turner JE. Photoreceptor repair in response to RPE transplants in RCS rats: outer segment regeneration. Curr Eye Res. 1996;15(10):1069-1077.
    • (1996) Curr Eye Res , vol.15 , Issue.10 , pp. 1069-1077
    • Lin, N.1    Fan, W.2    Sheedlo, H.J.3    Aschenbrenner, J.E.4    Turner, J.E.5
  • 62
    • 27244450331 scopus 로고    scopus 로고
    • Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes
    • Akagi T, Akita J, Haruta M, et al. Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes. Invest Ophthalmol Vis Sci. 2005;46(9):3411-3419.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.9 , pp. 3411-3419
    • Akagi, T.1    Akita, J.2    Haruta, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.