Lack of association of three GRIN2B polymorphisms with bipolar disorder

World Journal of Biological Psychiatry

Volumn 10, Issue 4 PART 2, 2009, Pages 469-473

  Szczepankiewicz, Aleksandra ^a   Skibinska, Maria ^a   Rybakowski, Janusz ^a   Leszczynska Rodziewicz, Anna ^a   Tomaszewska, Marta ^b   Twarowska Hauser, Joanna ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b NICOLAUS COPERNICUS UNIVERSITY   (Poland)

Author keywords

Association; Bipolar disorder; GRIN2B gene; Polymorphism

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADULT; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DNA POLYMORPHISM; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROTRANSMISSION; POLYMERASE CHAIN REACTION; PSYCHIATRIST; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHIZOPHRENIA; ALLELE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; POLAND; PSYCHOLOGICAL ASPECT;

ADULT; ALLELES; BIPOLAR DISORDER; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLAND; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 77449085467     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.1080/15622970802514968     Document Type: Article

References (34)

1. Avramopoulos D, Lasseter VK, Fallin MD, Wolyniec PS, McGrath JA, Nestadt G, et al. 2007. Stage II follow-up on a linkage scan for bipolar disorder in the Ashkenazim provides suggestive evidence for chromosome 12p and the GRIN2B gene. Genet Med 9:745-751.
2. Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265.
3. Benes FM, Todtenkopf MS, Kostoulakos P. 2001. GluR5,6,7 subunit immunoreactivity on apical pyramidal cell dendrites in hippocampus of schizophrenics and manic depressives. Hippocampus 11:482-491.
4. Cavalli-Sforza L. 1994. The history and geography of human genes. Englewood Cliffs, NJ: Princeton University Press.
5. Cull-Candy S, Brickley S, Farrant M. 2001. NMDA receptor subunits: diversity, development and disease. Curr Opin Neurobiol 11:327-335.
6. Di Maria E, Gulli R, Begni S, De Luca A, Bignotti S, Pasini A, et al. 2004. Variations in the NMDA receptor subunit 2B gene (GRIN2B) and schizophrenia: a case-control study. Am J Med Genet B Neuropsychiatr Genet 128B:27-29.
7. Dingledine R, Borges K, Bowie D, Traynelis SF. 1999. The glutamate receptor ion channels. Pharmacol Rev 51:7-61.
8. Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA, et al. 2005. Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am J Hum Genet 77:918-936.
9. Faraone SV, Su J, Tsuang MT. 2004. A genome-wide scan of symptom dimensions in bipolar disorder pedigrees of adult probands. J Affect Disord 82(Suppl 1):S71-78.
10. First MB, Spitzer RL, Gibbon M., Williams J. 1996. Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version (SCID-CV). Washington, DC: American Psychiatric Press.
11. Hollmann M, Boulter J, Maron C, Heinemann S. 1994. Molecular biology of glutamate receptors. Potentiation of N-methyl-D-aspartate receptor splice variants by zinc. Ren Physiol Biochem 17:182-183.
12. Ishii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, et al. 1993. Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. J Biol Chem 268:2836-2843.
13. Krupp JJ, Vissel B, Heinemann SF, Westbrook GL. 1996. Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific. Mol Pharmacol 50:1680-1688.
14. Laube B, Hirai H, Sturgess M, Betz H, Kuhse J. 1997. Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 18:493-503.
15. Laurie DJ, Schoeffter P, Wiederhold KH, Sommer B. 1997. Cloning, distribution and functional expression of the human mGlu6 metabotropic glutamate receptor. Neuropharmacology 36:145-152.
16. Law AJ, Deakin JF. 2001. Asymmetrical reductions of hippocam-pal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport 12:2971-2974.
17. Lerma J, Paternain AV, Rodriguez-Moreno A, Lopez-Garcia JC. 2001. Molecular physiology of kainate receptors. Physiol Rev 81:971-998.
18. Lijam N, Paylor R, McDonald MP, Crawley JN, Deng CX, Herrup K, et al. 1997. Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell 90:895-905.
19. Liou YJ, Wang YC, Chen JY, Bai YM, Lin CC, Liao DL, et al. 2007. Association analysis of polymorphisms in the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GRIN2B) gene and tardive dyskinesia in schizophrenia. Psychiatry Res
20. Mandich P, Schito AM, Bellone E, Antonacci R, Finelli P, Rocchi M, et al. 1994. Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12. Genomics 22:216-218.
21. Martucci L, Wong AH, De Luca V, Likhodi O, Wong GW, King N, et al. 2006. N-methyl-D-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: Polymorphisms and mRNA levels. Schizophr Res 84:214-221.
22. Miller SA, Dykes DD, Polesky HF 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215.
23. Miyatake R, Furukawa A, Suwaki H. 2002. Identification of a novel variant of the human NR2B gene promoter region and its possible association with schizophrenia. Mol Psychiatry 7:1101-1106.
24. Monyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H, et al. 1992. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256:1217-1221.
25. Nakanishi S, Nakajima Y, Masu M, Ueda Y, Nakahara K, Watanabe D, et al. 1998. Glutamate receptors: brain function and signal transduction. Brain Res Rev 26:230-235.
26. Ohtsuki T, Sakurai K, Dou H, Toru M, Yamakawa-Kobayashi K, Arinami T 2001. Mutation analysis of the NMDAR2B (GRIN2B) gene in schizophrenia. Mol Psychiatry 6:211-216.
27. Scannevin RH, Huganir RL. 2000. Postsynaptic organization and regulation of excitatory synapses. Nat Rev Neurosci 1:133-141.
28. Scarr E, Pavey G, Sundram S, MacKinnon A, Dean B. 2003. Decreased hippocampal NMDA, but not kainate or AMPA receptors in bipolar disorder. Bipolar Disord 5:257-264.
29. Schiffer HH. 2002. Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders? Mol Neurobiol 25:191-212.
30. Schito AM, Pizzuti A, Di Maria E, Schenone A, Ratti A, Defferrari R, et al. 1997. mRNA distribution in adult human brain of GRIN2B, a N-methyl-D-aspartate (NMDA) receptor subunit. Neurosci Lett 239:49-53.
31. Skibinska M, Hauser J, Czerski PM, Leszczynska-Rodziewicz A, Kosmowska M, Kapelski P, et al. 2004. Association analysis of brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder. World J Biol Psychiatry 5:215-220.
32. Szczepankiewicz A, Skibinska M, Hauser J, Slopien A, Leszczynska- Rodziewicz A, Kapelski P, et al. 2006b. Association analysis of the GSK-3beta T-50C gene polymorphism with schizophrenia and bipolar disorder. Neuropsychobiology 53:51-56. (Pubitemid 43254178)
33. Vicini S, Wang JF, Li JH, Zhu WJ, Wang YH, Luo JH, et al. 1998. Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. J Neurophysiol 79:555-566.
34. Wernicke C, Samochowiec J, Schmidt LG, Winterer G, Smolka M, Kucharska-Mazur J, et al. 2003. Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits. Biol Psychiatry 54:922-928.