Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes

BMC Molecular Biology

Volumn 11, Issue , 2010, Pages

  Mikula, Michal ^a,c   Hanusek, Karolina ^b   Paziewska, Agnieszka ^b   Dzwonek, Artur ^a   Rubel, Tymon ^a   Bomsztyk, Karol ^c   Ostrowski, Jerzy ^a,b  

^a INSTITUTE OF ONCOLOGY   (Poland)

^b MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIMETHYLOAMINO 4,5,6,7 TETRABROMO 1H BENZIMIDAZOLE; 4,5,6,7 TETRABROMOBENZIMIDAZOLE; CYCLIN DEPENDENT KINASE 9; EARLY GROWTH RESPONSE FACTOR 1; IMIDAZOLE DERIVATIVE; IMMEDIATE EARLY PROTEIN; MESSENGER RNA; RNA POLYMERASE II; UNCLASSIFIED DRUG; 2 DIMETHYLAMINO 4,5,6,7 TETRABROMO 1H BENZIMIDAZOLE; 2-DIMETHYLAMINO-4,5,6,7-TETRABROMO-1H-BENZIMIDAZOLE; 4,5,6,7-TETRABROMOBENZIMIDAZOLE; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; CASEIN KINASE II; EGR1 PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR;

ARTICLE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; RNA TRANSLATION; DRUG ANTAGONISM; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GENETICS; HALOGENATION; HELA CELL; METABOLISM;

ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CASEIN KINASE II; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CYCLIN-DEPENDENT KINASE 9; EARLY GROWTH RESPONSE PROTEIN 1; GENE EXPRESSION PROFILING; HALOGENATION; HELA CELLS; HUMANS; PROTEIN KINASE INHIBITORS; RNA POLYMERASE II; TRANSCRIPTION, GENETIC;

EID: 77349117561     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-11-4     Document Type: Article

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