Flat ductal intraepithelial neoplasia of the breast: Evolution of azzopardi's "clinging" concept

Seminars in Diagnostic Pathology

Volumn 27, Issue 1, 2010, Pages 37-48

  Moinfar, Farid ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Clinging carcinoma in situ; Columnar cell lesions; Early breast neoplasia; Flat ductal intraepithelial neoplasia; Flat epithelial atypia

Indexed keywords

ARTICLE; CANCER CLASSIFICATION; CANCER MORPHOLOGY; CARCINOGENESIS; CYTOARCHITECTURE; CYTOLOGY; DUCTAL INTRAEPITHELIAL NEOPLASIA; GENE LOCUS; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTRADUCTAL CARCINOMA; MALIGNANT TRANSFORMATION; NOMENCLATURE; PRECANCER; PRIORITY JOURNAL;

BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CELL NUCLEUS; DIAGNOSIS, DIFFERENTIAL; DISEASE PROGRESSION; DNA, NEOPLASM; FEMALE; FIBROCYSTIC BREAST DISEASE; HUMANS; LOSS OF HETEROZYGOSITY; PRECANCEROUS CONDITIONS; TERMINOLOGY AS TOPIC; TUMOR MARKERS, BIOLOGICAL;

EID: 77349101577     PISSN: 07402570     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semdp.2009.12.005     Document Type: Article

References (49)

1. Azzopardi J.G. Problems in Breast Pathology 1979, 193-203. W. B. Saunders Company, London, United Kingdom.
2. Moinfar F. Essentials of Diagnostic Breast Pathology 2007, Springer, Heidelberg, Germany.
3. Histological Typing of Breast Tumours 1981, International Histological Classification of Tumours, World Health Organization, Geneva, Switzerland. (ed 2).
4. Holland R., Peterse J.L., Millis R.R., et al. Ductal carcinoma in situ: A proposal for a new classification. Semin Diagn Pathol 1994, 11:167-180.
5. Tavassoli F.A. Pathology of the Breast 1992, Appleton & Lange, Norwalk, Connecticut. (ed 1).
6. Moinfar F., Man Y.G., Bratthauer G.L., et al. Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type ("clinging ductal carcinoma in situ"): A simulator of normal mammary epithelium. Cancer 2000, 88:2072-2081.
7. Fernandez-Aguilar S., Simon P., Buxant F., et al. Tubular carcinoma of the breast and associated intraepithelial lesions: A comparative study with invasive low-grade ductal carcinomas. Virchows Arch 2005, 447:683-687.
8. Sahoo S., Recant W.M. Triad of columnar cell alteration, lobular carcinoma in situ, and tubular carcinoma of the breast. Breast J 2005, 11:140-142.
9. Leibl S., Regitnig P., Moinfar F. Flat epithelial atypia (DIN1a, atypical columnar change): An underdiagnosed entity very frequently coexisting with lobular neoplasia. Histopathology 2007, 50:859-865.
10. Abdel-Fatah T.M.A., Powe D.G., Hodi Z., et al. High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. Am J Surg Pathol 2007, 31:417-426.
11. Oyama T., Lijima K., Takei H., et al. Atypical cystic lobules of the breast: An early stage of low-grade ductal carcinoma in situ. Breast Cancer 2000, 7:326-331.
12. Brogi E., Oyama T., Koerner F.C. Atypical cystic lobules in patients with lobular neoplasia. Int J Surg Pathol 2001, 9:201-206.
13. Wellings S.R., Jensen H.M., Marcum R.G. An atlas of subgross pathology of the human breast with special references to possible precancerous lesions. J Natl Cancer Inst 1975, 55:231-273.
14. Tsuchiya S. Atypical ductal hyperplasia, atypical lobular hyperplasia, and interpretation of a new borderline lesion. Jpn J Cancer Clin 1998, 44:548-555.
15. Kusama R., Fujimori M., Matsuyama I., et al. Clinicopathological characteristics of atypical cystic duct (ACD) of the breast: Assessment of ACD as a precancerous lesion. Pathol Int 2000, 50:793-800.
16. Schnitt S.J., Vincent-Salomon A. Columnar cell lesions of the breast. Adv Anat Pathol 2003, 10:113-124.
17. Simpson P.T., Gale T., Reis-Filho J.S., et al. Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis. Am J Surg Pathol 2005, 29:734-746.
18. Tan P.H., Ho B.C.-S., Selvarajan S., et al. Pathological diagnosis of columnar cell lesions of the breast: Are there issues of reproducibility?. J Clin Pathol 2008, 58:705-709.
19. Fraser J.L., Raza S., Chorny K., et al. Columnar alteration with prominent apical snouts and secretions: A spectrum of changes frequently present in breast biopsies performed for microcalcifications. Am J Surg Pathol 1998, 22:1521-1527.
20. Frazer J.L., Raza S., Chorny K., et al. Immunophenotype of columnar alteration with prominent apical snouts and secretions (abstract). Lab Invest 2000, 80:21A.
21. Dessauvagie B., Zhao W., Heel-Miller K.A., et al. Characterization of columnar cell lesion of the breast: Immunophenotypic analysis of columnar alteration of lobules with prominent apical snouts and secretion. Hum Pathol 2007, 38:284-292.
22. Rosen P.P. Columnar cell hyperplasia is associated with lobular carcinoma in situ and tubular carcinoma. Am J Surg Pathol 1999, 23:1561.
23. Rosen P.P. Breast Pathology 2001, Lippincott Williams & Wilkins, Philadelphia, PA. (ed 2).
24. Nasser S.M., Fan M.J. Does atypical columnar cell hyperplasia on breast core biopsy warrant follow-up excision?. Mod Pathol 2003, 16:42A. (abstract).
25. Nasser S.M. Columnar cell lesions: Current classification and controversies. Semin Diagn Pathol 2004, 21:18-24.
26. Goldstein N.S., O'Malley B.A. Cancerization of small ectatic ducts of the breast by ductal carcinoma in situ cells with apocrine snouts. A lesion associated with tubular carcinoma. Am J Clin Pathol 1997, 107:561-566.
27. Bratthauer G., Tavassoli F.A. Assessment of lesions coexisting with various grades of ductal intraepithelial neoplasia of the breast. Virchows Arch 2004, 444:340-344.
28. Schnitt S.J. Flat epithelial atypia-classification, pathologic features and clinical significance. Breast Cancer Res 2003, 5:263-268.
29. O'Malley F., Mohsen S., Badve S., et al. Interobserver reproducibility in the diagnosis of flat epithelial atypia of the breast. Mod Pathol 2006, 19:172-179.
30. Kunju L.P., Kleer C.G. Significance of flat epithelial atypia on mammotome core needle bioposy: Should it be excised?. Hum Pathol 2007, 38:35-41.
31. McLaren B.K., Gobbi H., Schuyler P.A., et al. Immunohistochemical expression of estrogen receptor in enlarged lobular units with columnar alteration in benign breast biopsies. A nested case-control study. Am J Surg Pathol 2005, 29:105-108.
32. Tavassoli F.A., Hoefler H., Rosai J., et al. Intraductal proliferative lesions. World Health Organization Classification of Tumours: Pathology and Genetics: Tumours of the Breast and Female Genital Organs 2003, Iarcpress, Lyon, France. F.A. Tavassoli, P. Devilee (Eds.).
33. Noel J.C., Fayt I., Fernandez-Aguilar S., et al. Proliferating activity in columnar cell lesions of the breast. Virchows Arch 2006, 449:617-621.
34. Dabbs D.J., Carter G., Fudge M., et al. Molecular alterations in columnar cell lesions of the breast. Mod Pathol 2006, 19:344-349.
35. Dutrillaux B., Gerbault-Seureau M., Zafrani B. Characterization of chromosomal anomalies in human breast cancer. Cancer Genet Cytogenet 1990, 49:203-217.
36. Kokalj-Vokac N., Alemeide A., Gerbault-Seureau M., et al. Two-color FISH characterization of i(1q) and der(1;16) in human breast cancer cells. Genes Chromosomes Cancer 1993, 7:8-14.
37. Eusebi V., Foschini M.P., Cook M.G., et al. Long-term follow-up of in situ carcinoma of the breast with special emphasize on clinging carcinoma. Semin Diagn Pathol 1989, 6:165-193.
38. Bijker N., Peterse J.L., Duchateau L., et al. Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma in situ: Analysis of European Organization for Research and Treatment of Cancer Trial 10853. J Clin Oncol 2001, 19:2263-2271.
39. Boulos F., Dupont W.D., Simpson J.F., et al. Histologic associations and long-term cancer risk in columnar cell lesions of the breast. A retrospective cohort and nested case-control study. Cancer 2008, 113:2415-2421.
40. Tavassoli F.A., Norris H.J. A comparison of the results of long-term follow-up for atypical intraductal hyperplasia and intraductal hyperplasia of the breast. Cancer 1990, 65:518-529.
41. Bodian C.A., Perzin K.H., Lattes R., et al. Prognostic significance of benign proliferative breast disease. Cancer 1993, 71:3896-3907.
42. Dupont W.D., Page D.L. Breast cancer risk associated with proliferative disease, age at first birth, and a family history of breast cancer. Am J Epidemiol 1987, 125:769-779.
43. Krieger N., Hiatt R.A. Risk of breast cancer after benign breast diseases. Variation by histologic type, degree of atypia, age at biopsy, and length of follow-up. Am J Epidemiol 1992, 135:619-631.
44. Bonnet M., Wallis T., Rossmann M., et al. Histologic analysis of atypia diagnosed on needle core breast biopsies (abstract). Mod Pathol 2002, 15:29A-30A.
45. Brogi E., Tan L.K. Findings an excisional biopsy (EBX) performed after identification of columnar cell change (CCC) of ductal epithelium in breast core biopsy (CBX) (abstract). Mod Pathol 2002, 15:29A-30A.
46. Guerra-Wallace M.M., Christensen W.N., White R.L. A retrospective study of columnar alteration with prominent apical snouts and secretions and the association with cancer. Am J Surg 2004, 188:395-398.
47. Kunju L.P., Kleer C.G. Significance of flat epithelial atypia (FEA) on mammotome core needle biopsy: Should it be excised?. Mod Pathol 2006, 19:32A. (abstract).
48. Martel M., Barron-Rodriguez P., Ocal I.T., et al. Flat DIN1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1751 core biopsies performed over an 8-year period (1992-1999). Virchows Arch 2007, 451:883-891.
49. Mascarel I., MacGrogan G., Mathoulin-Pelissier S., et al. Epithelial atypia in biopsies performed for microcalcifications. Practical considerations about 2833 serially sectioned surgical biopsies with long follow-up. Virchows Arch 2007, 451:1-10.