Drug-resistant tuberculosis in sub-Saharan Africa

Current Infectious Disease Reports

Volumn 12, Issue 1, 2010, Pages 36-45

  Hafkin, Jeffrey ^a   Gammino, Victoria M ^b   Amon, Joseph J ^c  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^c Health and Human Rights Division   (United States)

Author keywords

Drug resistant tuberculosis; HIV; Sub Saharan Africa

Indexed keywords

ABACAVIR; AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOSALICYLIC ACID; CAPREOMYCIN; CLARITHROMYCIN; CYCLOSERINE; DIDANOSINE; EFAVIRENZ; ETHIONAMIDE; ISONIAZID; KANAMYCIN; LINEZOLID; NEVIRAPINE; PROTEINASE INHIBITOR; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; STAVUDINE; TENOFOVIR; THIOACETAZONE; ZIDOVUDINE;

AFRICA SOUTH OF THE SAHARA; ANTIBIOTIC SENSITIVITY; BACTERIUM CULTURE; CYTOPENIA; DISEASE SURVEILLANCE; DRUG ANTAGONISM; DRUG ERUPTION; DRUG RESISTANT TUBERCULOSIS; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; GASTROINTESTINAL DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN RIGHTS; LEGAL ASPECT; LIVER TOXICITY; MEDICAL ETHICS; MEDICAL RESEARCH; MIXED INFECTION; MULTIDRUG RESISTANT TUBERCULOSIS; NEPHROTOXICITY; PERIPHERAL NEUROPATHY; PREVALENCE; PSYCHOSIS; REVIEW; SEIZURE; SLEEP DISORDER; TUBERCULOSIS CONTROL;

EID: 77249171316     PISSN: 15233847     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11908-009-0074-7     Document Type: Review

References (60)

1. EL Corbett B Marston GJ Churchyard, et al. 2006 Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment Lancet 367 926 937 10.1016/S0140-6736(06)68383-9 16546541
2. • Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis: Emergency Update 2008. Geneva: World Health Organization; 2008. Available at http://www.who.int/tb/publications/2008/programmatic-guidelines- for-mdrtb/en/index.html. Accessed February 2009. The World Health Organization provides a practical guide for managing drug-resistant TB in SSA and other resource-limited settings.
3. Stop TB Partnership: The Global Plan to Stop TB 2006-2015. Geneva: World Health Organization; 2006. Available at http://www.stoptb.org/globalplan/plan- main.asp. Accessed June 2009.
4. Chen L, Hanvoravongchai P: HIV/AIDS and human resources [editorial]. Bull World Health Organ 2005, 83:243-244. Available at http://www.who.int/bulletin/ volumes/83/4/en/index.html. Accessed October 2009.
5. Collins S, Baker BK, Gonsales G, et al.: The dangers of attacking disease-programmes for developing countries. BMJ 2007, 335:646. Available at http://www.bmj.com/cgi/eletters/335/7619/565#176912. Accessed June 2009.
6. •• Gandhi NR, Moll A, Sturm AW, et al.: Extensively drug-resistant tuberculosis as a cause of death in patients coinfected with tuberculosis and HIV in a rural area of South Africa. Lancet 2006, 368:1575-1580. This seminal paper highlights the emerging threat of XDR-TB in SSA.
7. •• Global Tuberculosis Control: Surveillance, Planning, Financing. Geneva: World Health Organization; 2008. Available at http://www.who.int/tb/publications/global-report/2008/en/index.html. Accessed February 2009. This report is an important overview of global TB epidemiology and international control efforts.
8. Joint United Nations Program on HIV/AIDS: Report on the Global HIV/AIDS Epidemic 2008. Available at http://www.unaids.org/en/KnowledgeCentre/HIVData/ GlobalReport/2008/2008-Global-report.asp. Accessed February 2009.
9. VM Gammino JJ Mboya T Samandari, et al. 2008 Baseline evaluation of routine HIV testing among tuberculosis patients in Botswana Int J Tuberc Lung Dis 12 3 Suppl 1 92 94 1:STN:280:DC%2BD1c3ktF2itg%3D%3D 18302830
10. JM Chakaya JR Mansoer F Scano, et al. 2008 National scale-up of HIV testing and provision of HIV care to tuberculosis patients in Kenya Int J Tuberc Lung Dis 12 424 429 1:STN:280:DC%2BD1c3ht1Ohug%3D%3D 18371269
11. HIV Provider-Initiated 2008 Testing and Counseling of TB Patients-Livingstone District, Zambia, September 2004-December 2006 MMWR Morb Mortal Wkly Rep 57 285 289
12. MA Aziz A Wright A Laszlo, et al. 2006 Epidemiology of antituberculosis drug resistance (the Global Project on Antituberculosis Drug Resistance Surveillance): an updated analysis Lancet 368 2142 2154 10.1016/S0140-6736(06) 69863-2 17174706 (Pubitemid 44914009)
13. CD Wells JP Cegielski LJ Nelson, et al. 2007 HIV infection and multidrug-resistant tuberculosis: the perfect storm J Infect Dis 196 Suppl 1 S86 S107 10.1086/518665 17624830 (Pubitemid 47206088)
14. Treatment of Tuberculosis: Guidelines for National Programmes, edn 3. Geneva: World Health Organization; 2003. Available at http://whqlibdoc.who.int/ HQ/2003/WHO-CDS-TB-2003.313-eng.pdf. Accessed February 2009.
15. TB/HIV: A Clinical Manual, edn 2. Geneva: World Health Organization; 2004. Available at http://www.who.int/tb/publications/who-htm-tb-2004-329/en/ index.html. Accessed February 2009.
16. Getahun H, Harrington M, O'Brien R, Nunn P: Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resource-constrained settings: informing urgent policy changes. Lancet 2007, 369:2042-2049. Available at http://www.thelancet.com/journals/lancet/article/ PIIS0140-6736(07)60284-0/fulltext. Accessed February 2009.
17. AM Elliott K Namaambo BW Allen 1993 Negative sputum smear results in HIV-positive patients with pulmonary tuberculosis in Lusaka, Zambia Tuber Lung Dis 74 191 194 10.1016/0962-8479(93)90010-U 1:STN:280:DyaK3sznvFamug%3D%3D 8369514 (Pubitemid 23188682)
18. L Aaron D Saadoun I Calatroni, et al. 2004 Tuberculosis in HIV-infected patients: a comprehensive review Clin Microbiol Infect 10 388 398 10.1111/j.1469-0691.2004.00758.x 1:STN:280:DC%2BD2c3hsFyiuw%3D%3D 15113314 (Pubitemid 38714564)
19. MJ Reid NS Shah 2009 Approaches to tuberculosis screening and diagnosis in people with HIV in resource-limited settings Lancet Infect Dis 9 173 184 10.1016/S1473-3099(09)70043-X 19246021
20. GL Woods 2002 The mycobacteriology laboratory and new diagnostic techniques Infect Dis Clin North Am 16 127 144 10.1016/S0891-5520(03)00049-7 11917810 (Pubitemid 34234947)
21. GL Woods 2000 Susceptibility testing for mycobacteria Clin Infect Dis 31 1209 1215 10.1086/317441 1:CAS:528:DC%2BD3MXhsVKhug%3D%3D 11073754 (Pubitemid 32295452)
22. MD Perkins J Cunningham 2007 Facing the crisis: improving the diagnosis of tuberculosis in the HIV era J Infect Dis 196 Suppl 1 15 27 10.1086/518656 (Pubitemid 47206081)
23. Yurtsever L, van Dijk JH, van der Poel MG: The added value of introducing MGIT culturing method to direct smear method in the diagnosis of tuberculosis in the Medical Institute at Macha, Macha, Zambia [abstract pD-1122]. Presented at the 48th International Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2008). Washington, DC; October 25-28, 2008.
24. IK Neonakis Z Gitti E Krambovitis, et al. 2008 Molecular diagnostic tools in mycobacteriology J Microbiol Methods 75 1 11 10.1016/j.mimet.2008.05.023 1:CAS:528:DC%2BD1cXps1GmtLs%3D 18599139
25. World Health Organization: Molecular Line Probe Assays for Rapid Screening of Patients at Risk of Multidrug-Resistant Tuberculosis (MDR-TB): WHO Policy Statement, June 27, 2008. Available at http://www.who.int/tb/features- archive/policy-statement.pdf. Accessed February 2009.
26. MA Espinal SJ Kim PG Suarez, et al. 2000 Standard short-course chemotherapy for drug-resistant tuberculosis, treatment outcomes in 6 countries JAMA 283 2537 2545 10.1001/jama.283.19.2537 1:CAS:528:DC%2BD3cXjvVemu74%3D 10815117
27. R Gupta JP Cegielski MA Espinal, et al. 2002 Increasing transparency in partnerships for health-introducing the Green Light Committee Trop Med Int Health 7 970 976 10.1046/j.1365-3156.2002.00960.x 12390604 (Pubitemid 35356618)
28. Jamison DT, Feachem RG, Makgoba MW, et al., eds.: Disease and Mortality in Sub-Saharan Africa, edn 2. Washington, DC: The World Bank; 2006. Available at http://www.dcp2.org/file/66/Disease%20and%20Mortality%20in%20SSA.pdf. Accessed February 2009.
29. VLC White J Moore-Gillon 2000 Resource implications of patients with multidrug resistant tuberculosis Thorax 55 962 963 10.1136/thorax.55.11.962 1:STN:280:DC%2BD3M%2FlslGitQ%3D%3D 11050268 (Pubitemid 30831976)
30. J Moore-Gillon 2001 Multidrug-resistant tuberculosis: this is the cost Ann N Y Acad Sci 953 233 240 10.1111/j.1749-6632.2001.tb11382.x 1:STN:280:DC%2BD38%2FmvFOlsQ%3D%3D 11795417
31. World Health Organization Stop TB Partnership Coordinating Board: Improving the Supply of and Demand for Quality-Assured Second-line TB Drugs: Background Paper. Published October 2008. Available at http://www.stoptb.org/cb/ meetings/20081028-Bagamoyo-Tanzania/assets/documents/2.08-10. 1%202nd%20line%20drugs%20Background%20Paper.pdf. Accessed February 2009.
32. World Health Organization: Green Light Committee Initiative of the Working Group on MDR-TB of the Stop TB Partnership: Annual Report 2007. Published 2008. Available at http://whqlibdoc.who.int/hq/2008/WHO-HTM-TB-2008. 409-eng.pdf. Accessed February 2009.
33. F Scano M Vitoria W Burman, et al. 2008 Management of HIV-infected patients with MDR- and XDR-TB in resource-limited settings Int J Tuberc Lung Dis 12 1370 1375 1:STN:280:DC%2BD1cjlt1Smtw%3D%3D 19017444
34. Francis J. Curry National Tuberculosis Center and California Department of Public Health: Drug-Resistant Tuberculosis: A Survival Guide for Clinicians, edn 2. Published 2008. Available at http://www.nationaltbcenter.ucsf.edu/drtb/. Accessed February 2009.
35. Rich ML, ed: The PIH Guide to the Medical Management of Multidrug-Resistant Tuberculosis, International Edition. Boston: Partners in Health; 2003. Available at http://www.pih.org/inforesources/pihguide-mdrtb.html. Accessed February 2009.
36. P Nunn D Kibuga S Gathua, et al. 1991 Cutaneous hypersensitivity reactions due to thiacetazone in HIV-1 seropositive patients treated for tuberculosis Lancet 337 627 630 10.1016/0140-6736(91)92447-A 1:STN:280:DyaK3M7lsFKiug%3D%3D 1705647
37. SD Lawn L Myer LG Bekker, et al. 2007 Tuberculosis-associated immune reconstitution disease: incidence, risk factors and impact in an antiretroviral treatment service in South Africa AIDS 21 335 341 10.1097/QAD.0b013e328011efac 17255740 (Pubitemid 46175045)
38. G Meintjes MX Rangaka G Maartens, et al. 2009 Novel relationship between tuberculosis immune reconstitution inflammatory syndrome and antitubercular drug resistance Clin Infect Dis 48 667 679 10.1086/596764 19191655
39. CA Petti CR Polage TC Quinn, et al. 2006 Laboratory medicine in Africa: a barrier to effective health care Clin Infect Dis 42 377 82 10.1086/499363 16392084 (Pubitemid 43122314)
40. NN Bock PA Jensen B Miller E Nardell 2007 Tuberculosis infection control in resource-limited settings in the era of expanding HIV care and treatment J Infect Dis 196 Suppl 1 108 113 10.1086/518661 (Pubitemid 47206089)
41. Centers for Disease Control and Prevention, World Health Organization, and International Union Against Tuberculosis and Lung Disease: Tuberculosis Infection Control in the Era of Expanding HIV Care and Treatment: Addendum to WHO Guidelines for the Prevention of Tuberculosis in Health Care Facilities in Resource-Limited Settings. Available at http://www.who.int/tb/publications/who- tb-99-269/en/index.html. Accessed February 2009.
42. S Basu JR Andrews EM Poolman, et al. 2007 Prevention of nosocomial transmission of extensively drug-resistant tuberculosis in rural South African district hospitals: an epidemiological modeling study Lancet 370 1500 07 10.1016/S0140-6736(07)61636-5 17964351 (Pubitemid 47628865)
43. AR Escombe CC Oeser RH Gilman, et al. 2007 Natural ventilation for the prevention of airborne contagion PLoS Medicine 4 309 317 10.1371/journal.pmed. 0040309 (Pubitemid 350220531)
44. JR Andrews NR Gandhi P Moodley 2008 Exogenous reinfection as a cause of multidrug-resistant and extensively drug-resistant tuberculosis in rural South Africa J Infect Dis 198 1582 1589 10.1086/592991 18847372
45. Amon JJ, Girard F, Keshavjee S: Limitations on human rights in the context of drug-resistant tuberculosis: a reply to Boggio et al. [Perspectives]. Health and Human Rights: An International Journal. Available at http://hhrjournal.org/blog/wp-content/uploads/2009/10/amon.pdf. Accessed October 2009.
46. AIDS Law Project: protecting public health and human rights in the response to TB in South Africa: state and individual responsibilities. Available at http://server.alp.org.za/ProtectingPublicHealth.pdf. Published March 2009. Accessed October 2009.
47. Dugger CW: TB patients chafe under lockdown in South Africa. New York Times. March 25, 2008. Available at http://www.nytimes.com/2008/03/25/world/ africa/25safrica.html #. Accessed October 2009.
48. Baleta A: Forced isolation of tuberculosis patients in South Africa. Lancet Infect Dis 2007, 7:771. Available at http://www.thelancet.com/journals/ laninf/article/PIIS1473-3099(07)70281-5/fulltext. Accessed February 2009.
49. United Nations Economic and Social Council, UN Sub-Commission on Prevention of Discrimination and Protection of Minorities: Siracusa Principles on the Limitation and Derogation Provisions in the International Covenant on Civil and Political Rights (1985). UN Document E/CN.4/1985/4. Available at http://www1.umn.edu/humanrts/instree/siracusaprinciples.html. Accessed October 2009.
50. • Singh JR, Upshur R, Padayatch N: XDR-TB in South Africa: no time for denial or complacency. PLoS Medicine 2007, 4:19-25. This article provides an important overview of the ethical issues facing TB control efforts in the era of XDR-TB.
51. Integrated Regional Information Networks (IRIN)/PlusNews Global HIV/AIDS News and Analysis: Lesotho, South Africa: Cross-border health crisis hits mineworkers. Available at http://www.plusnews.org/Report.aspx?ReportId=83027. Accessed February 2009.
52. Smart T: Migrants with MDR-TB in Southern Africa being dumped off at borders without referrals to care. Aidsmap. October 31, 2008. Available at http://www.aidsmap.com/en/news/F776AAFE-AB53-42B7-81BA-85C3E6426171.asp. Accessed October 2009.
53. MJ Selgelid PM Kelly A Sleigh 2008 Ethical challenges in TB control in the era of XDR-TB Int J Tuberc Lung Dis 12 231 235 1:STN:280: DC%2BD1c3isFSisw%3D%3D
54. MJ Selgelid 2008 Ethics, tuberculosis and globalization Public Health Ethics 1 10 20 10.1093/phe/phn001
55. K Weyer M van der Wal P Kantor 2006 Managing multidrug-resistant tuberculosis: legal implications MRC Policy Brief 1 1 4
56. AS Fauci 2008 NIAID Tuberculosis Working Group: Multidrug-resistant and extensively drug-resistant tuberculosis: the National Institute of Allergy and Infectious Diseases research agenda and recommendations for priority research J Infect Dis 197 1493 1498 10.1086/587904 18426366 (Pubitemid 351706477)
57. FG Cobelens E Heldal ME Kimerling, et al. 2008 Scaling up programmatic management of drug-resistant tuberculosis: a prioritized research agenda PLoS Medicine 5 e150 10.1371/journal.pmed.0050150 18613746
58. N Schluger U Karunakara C Lienhardt, et al. 2007 Building clinical trials capacity for tuberculosis drugs in high-burden countries PLoS Medicine 4 e302 10.1371/journal.pmed.0040302 17988170 (Pubitemid 350220526)
59. Foundation for Innovative New Diagnostics. Available at http://www.finddiagnostics.org/. Accessed February 2009.
60. Global Alliance for TB Drug Development. Available at http://www.tballiance.org/home/home.php. Accessed February 2009.