Glycosylphosphatidylinositols are potential targets for the development of novel inhibitors for aerolysin-type of pore-forming bacterial toxins

Medicinal Research Reviews

Volumn 30, Issue 2, 2010, Pages 258-269

  Wu, Qiuye ^a   Guo, Zhongwu ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

Aerolysin; Carbohydrate; Glycolipid; GPI; Pore forming toxin; Toxin inhibitor

Indexed keywords

AEROLYSIN; BACTERIAL TOXIN; GLYCOSYLPHOSPHATIDYLINOSITOL; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL DERIVATIVE; PORE FORMING BACTERIAL TOXIN; UNCLASSIFIED DRUG;

CHANNEL GATING; DRUG STRUCTURE; DRUG SYNTHESIS; HOST PATHOGEN INTERACTION; HUMAN; MOLECULAR INTERACTION; NONHUMAN; REACTION ANALYSIS; REVIEW; STRUCTURE ANALYSIS;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; CARBOHYDRATES; CELL MEMBRANE; GLYCOLIPIDS; GLYCOPROTEINS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MODELS, CHEMICAL; POLYSACCHARIDES; PORE FORMING CYTOTOXIC PROTEINS; TIME FACTORS;

EID: 77249145364     PISSN: 01986325     EISSN: 10981128     Source Type: Journal    
DOI: 10.1002/med.20167     Document Type: Review

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