-
1
-
-
0034488052
-
Clinical implications of Dihydropyrimidine Dehydrogenase (DPD) deficiency in patients with severe 5- Fluorouracil-associated toxicity: Identification of new mutations in the DPD gene
-
A.B.P. van Kuilenburg, J. Sajes, D.J. Richel, L. Zoetekouw, H.V. Lenthe, R.A. De Abreu, J.G. Maring, P. Vreken and A.H. van Gennip, Clinical implications of Dihydropyrimidine Dehydrogenase (DPD) deficiency in patients with severe 5- Fluorouracil-associated toxicity: Identification of new mutations in the DPD gene, Clinical Cancer Research 6 (2000), 4705-4712.
-
(2000)
Clinical Cancer Research
, vol.6
, pp. 4705-4712
-
-
Van Kuilenburg, A.B.P.1
Sajes, J.2
Richel, D.J.3
Zoetekouw, L.4
Lenthe, H.V.5
Abreu De, R.A.6
Maring, J.G.7
Vreken, P.8
Gennip Van, A.H.9
-
2
-
-
0034901306
-
Lethal outcome of a patient with a complete Dihydropyrimidine Dehydrogenase (DPD) deficiency after administration of 5-Fluorouracil: Frequency of the common IVS14+1G>A mutation causing DPD deficiency
-
A.B.P. van Kuilenburg, E.W. Muller, J. Sajes, R. Meinsma, L. Zoetekouw, H.R. Waterham, F. Baas, D.J. Richel and A.H. van Gennip, Lethal outcome of a patient with a complete Dihydropyrimidine Dehydrogenase (DPD) deficiency after administration of 5-Fluorouracil: Frequency of the common IVS14+1G>A mutation causing DPD deficiency, Clinical Cancer Research 7 (2001), 1149-1153.
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 1149-1153
-
-
Van Kuilenburg, A.B.P.1
Muller, E.W.2
Sajes, J.3
Meinsma, R.4
Zoetekouw, L.5
Waterham, H.R.6
Baas, F.7
Richel, D.J.8
Gennip Van, A.H.9
-
3
-
-
0030934850
-
Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for Azathioprine and Mercaptopurine intolerance
-
C.R. Yates, E.Y. Krynetski, T. Loennechen, M.Y. Fessing, H. Tai, C. Pui, M.V. Relling andW.E. Evans, Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for Azathioprine and Mercaptopurine intolerance, Annals of Internal Medicine 126 (1997), 608-614.
-
(1997)
Annals of Internal Medicine
, vol.126
, pp. 608-614
-
-
Yates, C.R.1
Krynetski, E.Y.2
Loennechen, T.3
Fessing, M.Y.4
Tai, H.5
Pui, C.6
Relling, M.V.7
Evans, W.E.8
-
4
-
-
12644291917
-
Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms
-
D. Otterness, B.S.C. Szumlanski, B.S.L. Lennard, B. Klemetsdal, J. Aarbakke, J. Ok Park-Hah, H. Iven, K Schmiegelow, E. Branum, J. O'Brien, R. Weinshilboum, Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms, Clin Pharmacol Ther 62 (1997), 60-73.
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 60-73
-
-
Otterness, D.1
Szumlanski, B.S.C.2
Lennard, B.S.L.3
Klemetsdal, B.4
Aarbakke, J.5
Ok Park-Hah, J.6
Iven, H.7
Schmiegelow, K.8
Branum, E.9
O'Brien, J.10
Weinshilboum, R.11
-
6
-
-
0043163813
-
High throughput genotyping by DHPLC of the Dihydropyrimidine Dehydrogenase gene implicated in (fluoro)pyrimidine catabolism
-
E. Gross, K. Seck, S. Neubauer, J. Mayr, H. Hellebrand, A. Ratanaphan, V. Lutz, H. Stokinger and M. Kiechle, High throughput genotyping by DHPLC of the Dihydropyrimidine Dehydrogenase gene implicated in (fluoro)pyrimidine catabolism, International Journal of Oncology 22 (2003), 325-332.
-
(2003)
International Journal of Oncology
, vol.22
, pp. 325-332
-
-
Gross, E.1
Seck, K.2
Neubauer, S.3
Mayr, J.4
Hellebrand, H.5
Ratanaphan, A.6
Lutz, V.7
Stokinger, H.8
Kiechle, M.9
-
7
-
-
0028861745
-
A single point mutsion leading to loss of catalytic activity in human thiopurine S-Methyltransferase
-
E.Y. Krynetski, J.D. Schuetz, A.J. Galpin, C. Pui, M.V. Relling and W.E. Evans, A single point mutsion leading to loss of catalytic activity in human thiopurine S-Methyltransferase, Proceedings of National Academy of Sciences USA 92 (1995) 949-953.
-
(1995)
Proceedings of National Academy of Sciences USA
, vol.92
, pp. 949-953
-
-
Krynetski, E.Y.1
Schuetz, J.D.2
Galpin, A.J.3
Pui, C.4
Relling, M.V.5
Evans, W.E.6
-
8
-
-
3142724744
-
Pharmacogenetics of thiopurines: Can posology be guided by laboratory data
-
G. Stocco, S. Martelossi, G. Decorti, A. Ventura, N. Malusaq, F. Biartoli and T. Giraldi, Pharmacogenetics of thiopurines: can posology be guided by laboratory data, Radiol Oncol 38 (2004), 101-109.
-
(2004)
Radiol Oncol
, vol.38
, pp. 101-109
-
-
Stocco, G.1
Martelossi, S.2
Decorti, G.3
Ventura, A.4
Malusaq, N.5
Biartoli, F.6
Giraldi, T.7
-
9
-
-
0030986251
-
Enhanced proteolysis of thiopurine Smethyltransferase (TPMT) encoded by mutant allele in humans (TPMT *3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity
-
H. Tai, E.Y. Krynetski, E.G. Schetz, Y. Yanishevski and W.E. Evans, Enhanced proteolysis of thiopurine Smethyltransferase (TPMT) encoded by mutant allele in humans (TPMT *3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity, Proceedings of National Academy of Sciences USA 94 (1997), 6444-6449.
-
(1997)
Proceedings of National Academy of Sciences USA
, vol.94
, pp. 6444-6449
-
-
Tai, H.1
Krynetski, E.Y.2
Schetz, E.G.3
Yanishevski, Y.4
Evans, W.E.5
-
11
-
-
0036303541
-
Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype
-
M.R. Johnson, K. Wang and R.B. Diasio, Profound Dihydropyrimidine Dehydrogenase Deficiency resulting from a novel compound heterozygote genotype, Clincal Cancer Research 8 (2002), 768-774.
-
(2002)
Clincal Cancer Research
, vol.8
, pp. 768-774
-
-
Johnson, M.R.1
Wang, K.2
Diasio, R.B.3
-
12
-
-
0034808681
-
Prevalence of a common point mutation in the Dihydropyrimidine Dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-Fluorouracil (5-FU)-related toxicity compared with controls
-
M. Raida, W. Schwabe, P. Hausler, A.B.P. Van Kuilenburg, A.H. Van Gennip, D. Behnke and K. Hoffken, Prevalence of a common point mutation in the Dihydropyrimidine Dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-Fluorouracil (5-FU)-related toxicity compared with controls, Clinical Cancer Research 7 (2001), 2832-2839.
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 2832-2839
-
-
Raida, M.1
Schwabe, W.2
Hausler, P.3
Van Kuilenburg, A.B.P.4
Gennip Van, A.H.5
Behnke, D.6
Hoffken, K.7
-
13
-
-
4344650951
-
Rapid, long-range molecular haplotyping of Thiopurine Smethyltransferase (TPMT) * 3A, *3B and *3C
-
N. von Ahsen, V.W. Armstrong and M. Oellerich, Rapid, long-range molecular haplotyping of Thiopurine Smethyltransferase (TPMT) *3A, *3B and *3C, Molecular Diagnostics and Genetics 50 (2004), 1528-1534.
-
(2004)
Molecular Diagnostics and Genetics
, vol.50
, pp. 1528-1534
-
-
Von Ahsen, N.1
Armstrong, V.W.2
Oellerich, M.3
-
14
-
-
0032748608
-
Dihydropyrimidine Dehydrogenase: Its role in 5-Fluorouracil Clinical Toxicity and Tumor Resistance
-
R.B. Diasio and M.R. Johnson, Dihydropyrimidine Dehydrogenase : Its role in 5-Fluorouracil Clinical Toxicity and Tumor Resistance, Clinical Cancer Research 5 (1999), 2672-2673.
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 2672-2673
-
-
Diasio, R.B.1
Johnson, M.R.2
-
15
-
-
7344249042
-
Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects
-
DOI 10.1046/j.1365-2125.1998.00751.x
-
S.A. Ridge, J. Sludden, O. Brown, L. Robertson, X. Wei, A. Sapone, P.M. Fernandez-Salguero, F.J. Gonzalez, P. Vreken, A.B.P. van Kuilenburg, A.H. van Gennip and H.L. McLeod, Dihydropyrimidine Dehydrogenase pharmacogenetics in Caucasian subjects, British Journal of Clinical Pharmacology 46 (1998), 151-156. (Pubitemid 28342786)
-
(1998)
British Journal of Clinical Pharmacology
, vol.46
, Issue.2
, pp. 151-156
-
-
Ridge, S.A.1
Sludden, J.2
Brown, O.3
Robertson, L.4
Wei, X.5
Sapone, A.6
Fernandez-Salguero, P.M.7
Gonzalez, F.J.8
Vreken, P.9
Van Kuilenburg, A.B.P.10
Van Gennip, A.H.11
McLeod, H.L.12
-
16
-
-
0024284028
-
A simple salting out procedure for extracting DNAfrom human nucleated cells
-
S.K. Miller, D.D. Dykes and H.F. Polesky, A simple salting out procedure for extracting DNAfrom human nucleated cells, Nucleic Acids Res 19 (1998), 1215.
-
(1998)
Nucleic Acids Res
, vol.19
, pp. 1215
-
-
Miller, S.K.1
Dykes, D.D.2
Polesky, H.F.3
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