Association between avian necrotic enteritis and Clostridium perfringens strains expressing NetB toxin

Veterinary Research

Volumn 41, Issue 2, 2010, Pages

  Keyburn, Anthony L ^a,b,c   Yan, Xu Xia ^b   Bannam, Trudi L ^b   Van Immerseel, Filip ^d   Rood, Julian I ^b,c   Moore, Robert J ^a,b,c  

^a CSIRO   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c Department of Civil and Environmental Engineering   (Australia)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

Clostridium perfringens; Necrotic enteritis; NetB toxin; TpeL; Virulence factor

Indexed keywords

AVES; CLOSTRIDIUM PERFRINGENS; GALLUS GALLUS;

BACTERIAL TOXIN; ENTEROTOXIN; NETB PROTEIN, CLOSTRIDIUM PERFRINGENS;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIRD DISEASE; CHICKEN; CLOSTRIDIUM PERFRINGENS; ENTERITIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; VIRULENCE;

ANIMALS; BACTERIAL TOXINS; CHICKENS; CLOSTRIDIUM PERFRINGENS; ENTERITIS; ENTEROTOXINS; GENE EXPRESSION REGULATION, BACTERIAL; POULTRY DISEASES; VIRULENCE;

EID: 77249116209     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1051/vetres/2009069     Document Type: Article

References (23)

1. Al-Sheikhly F., Truscott R.B., The pathology of necrotic enteritis of chickens following infusion of broth cultures of Clostridium perfringens into the duodenum, Avian Dis. (1977) 21:230-240.
2. Al-Sheikhly F., Truscott R.B., The pathology of necrotic enteritis of chickens following infusion of crude toxins of Clostridium perfringens into the duodenum, Avian Dis. (1977) 21:241-255.
3. Chalmers G., Bruce H.L., Hunter D.B., Parreira V.R., Kulkarni R.R., Jiang Y.F., et al., Multilocus sequence typing analysis of Clostridium perfringens isolates from necrotic enteritis outbreaks in broiler chicken populations, J. Clin. Microbiol. (2008) 46:3957-3964.
4. Chalmers G., Martin S.W., Hunter D.B., Prescott J.F., Weber L.J., Boerlin P., Genetic diversity of Clostridium perfringens isolated from healthy broiler chickens at a commercial farm, Vet. Microbiol. (2008) 127:116-127.
5. Cooper K.K., Songer J.G., Necrotic enteritis in chickens: a paradigm of enteric infection by Clostridium perfringens type A, Anaerobe (2009) 15:55-60.
6. Crespo R., Fisher D.J., Shivaprasad H.L., Fernandez-Miyakawa M.E., Uzal F.A., Toxinotypes of Clostridium perfringens isolated from sick and healthy avian species, J. Vet. Diagn. Invest. (2007) 19:329-333.
7. Drigo I., Agnoletti F., Bacchin C., Bettini F., Cocchi M., Ferro T., et al., Toxin genotyping of Clostridium perfringens field strains isolated from healthy and diseased chickens, Ital. J. Anim. Sci. (2008) 7:397-400.
8. Engstrom B.E., Fermer C., Lindberg A., Saarinen E., Baverud V., Gunnarsson A., Molecular typing of isolates of Clostridium perfringens from healthy and diseased poultry, Vet. Microbiol. (2003) 94:225-235.
9. Fukata T., Hadate Y., Baba E., Uemura T., Arakawa A., Influence of Clostridium perfringens and its toxin in germ-free chickens, Res. Vet. Sci. (1988) 44:68-70.
10. Gholamiandekhordi A.R., Ducatelle R., Heyndrickx M., Haesebrouck F., Van Immerseel F., Molecular and phenotypical characterization of Clostridium perfringens isolates from poultry flocks with different disease status, Vet. Microbiol. (2006) 113:143-152.
11. Keyburn A.L., Sheedy S.A., Ford M.E., Williamson M.M., Awad M.M., Rood J.I., Moore R.J., Alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens, Infect. Immun. (2006) 74:6496-6500.
12. Keyburn A.L., Boyce J.D., Vaz P., Bannam T.L., Ford M.E., Parker D., et al., NetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens, PLoS Pathog. (2008) 4:e26.
13. Leslie D., Fairweather N., Pickard D., Dougan G., Kehoe M., Phospholipase C and haemolytic activities of Clostridium perfringens alpha-toxin cloned in Escherichia coli: sequence and homology with a Bacillus cereus phospholipase C, Mol. Microbiol. (1989) 3:383-392.
14. Martin T.G., Smyth J.A., Prevalence of netB among some clinical isolates of Clostridium perfringens from animals in the United States, Vet. Microbiol. (2009) 136:202-205.
15. Menestrina G., Serra M.D., Prevost G., Mode of action of beta-barrel pore-forming toxins of the staphylococcal alpha-hemolysin family, Toxicon (2001) 39:1661-1672.
16. Nauerby B., Pedersen K., Madsen M., Analysis by pulsed-field gel electrophoresis of the genetic diversity among Clostridium perfringens isolates from chickens, Vet. Microbiol. (2003) 94:257-266.
17. O'Connor J.R., Lyras D., Farrow K.A., Adams V., Powell D.R., Hinds J., et al., Construction and analysis of chromosomal Clostridium difficile mutants, Mol. Microbiol. (2006) 61:1335-1351.
18. Rood J.I., Virulence genes of Clostridium perfringens, Annu. Rev. Microbiol. (1998) 52:333-360.
19. Sheedy S.A., Ingham A.B., Rood J.I., Moore R.J., Highly conserved alpha-toxin sequences of avian isolates of Clostridium perfringens, J. Clin. Microbiol. (2004) 42:1345-1347.
20. Songer J.G., Clostridial enteric diseases of domestic animals, Clin. Microbiol. Rev. (1996) 9:216-234.
21. Timbermont L., Lanckriet A., Gholamiandehkordi A.R., Pasmans F., Martel A., Haesebrouck F., et al., Origin of Clostridium perfringens isolates determines the ability to induce necrotic enteritis in broilers, Comp. Immunol. Microbiol. Infect. Dis. (2009) 32:503-512.
22. Van Immerseel F., Rood J.I., Moore R.J., Titball R.W., Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens, Trends Microbiol. (2009) 17:32-36.
23. Vidal J.E., McClane B.A., Saputo J., Parker J., Uzal F.A., Effects of Clostridium perfringens betatoxin on the rabbit small intestine and colon, Infect. Immun. (2008) 76:4396-4404.