Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine

Journal of the American Chemical Society

Volumn 132, Issue 6, 2010, Pages 1802-1803

  Perl, Nicholas R ^a   Ide, Nathan D ^b   Prajapati, Sudeep ^a   Perfect, Hahdi H ^a,b   Durón, Sergio G ^b   Gin, David Y ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2-AMINOPYRIMIDINE; 2-AMINOPYRIMIDINES; CARBODIIMIDES; CONVERGENT SYNTHESIS; CRAMBIDINE; HYDROAMINATIONS;

ACETYLENE; ISOMERS; NUCLEOPHILES;

SYNTHESIS (CHEMICAL);

ALKYNE DERIVATIVE; CRAMBIDINE; CYANAMIDE; NUCLEOPHILE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ALKYLATION; ANNULATION REACTION; ARTICLE; CHEMICAL BOND; SYNTHESIS;

ALKYNES; AMINATION; CARBODIIMIDES; GUANIDINE; IMIDOESTERS; PYRIMIDINES; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 77249115235     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja910831k     Document Type: Article

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