Total synthesis of crambescidin 359

Organic Letters

Volumn 4, Issue 2, 2002, Pages 177-180

  Nagasawa, Kazuo ^a   Georgieva, Angelina ^a   Koshino, Hiroyuki ^a   Nakata, Tadashi ^a   Kita, Tetsuya ^b   Hashimoto, Yuichi ^b  

^a RIKEN   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; CALCIUM CHANNEL BLOCKING AGENT; CRAMBESCIDIN 359; GUANIDINE; PTILOMYCALIN A; SPIRO COMPOUND;

ANIMAL; ARTICLE; CHEMISTRY; CONFORMATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPONGE (PORIFERA); STEREOISOMERISM; SYNTHESIS;

ALKALOIDS; ANIMALS; CALCIUM CHANNEL BLOCKERS; GUANIDINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PORIFERA; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 0037165358     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0168263     Document Type: Article

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38. We thank Prof. Braekman for providing copies of spectra of crambescidin 359 (4).
39. The counteranion of natural 4 was not reported. The coincidence of the spectral data as well as the optical rotation of synthetic 4 chloride salt and the natural products would suggest that the counteranion of the natural product is chloride.
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