Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria

Pharmaceutical Biology

Volumn 48, Issue 3, 2010, Pages 260-263

  Ramos, Daniela Fernandes ^a   Da Silva, Pedro Eduardo Almeida ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE   (Brazil)

Author keywords

Efflux; Mycobacterium tuberculosis; Nontuberculous mycobacteria; Resistance; Usnic acid

Indexed keywords

ANTIBIOTIC AGENT; ANTIMYCOBACTERIAL AGENT; USNIC ACID;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DISEASE CONTROL; DRUG ACTIVITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PUBLIC HEALTH PROBLEM; TUBERCULOSIS;

ANTI-BACTERIAL AGENTS; BENZOFURANS; CALCIUM CHANNEL BLOCKERS; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, BACTERIAL; IONOPHORES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; NONTUBERCULOUS MYCOBACTERIA; TUBERCULOSIS, MULTIDRUG-RESISTANT; VERAPAMIL;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 77249103530     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903085490     Document Type: Article

References (23)

1. Azevedo LG, Muccillo-Baisch AL, Filgueira DM, Boyle RT, Ramos DF, Soares AD, Lerner C, Silva PA, Trindade GS (2008): Comparative cytotoxic and anti-tuberculosis activity of Aplysina caissara marine sponge crude extracts. Comp Biochem Physiol C Toxicol Pharmacol 147: 36-42.
2. Bazin MA, Lamer AC, Delcros JG, Rouaud I, Uriac P, Boustie J, Corbel JC, Tomasi S (2008): Synthesis and cytotoxic activities of usnic acid derivatives. Bioorg Med Chem 16: 6860-6866.
3. Cocchietto M, Skert N, Nimis PL, Sava G (2002): A review on usnic acid, an interesting natural compound. Naturwissenschaften 89: 137-146.
4. Copp BR, Pearce AN (2007): Natural product growth inhibitors of Mycobacterium tuberculosis. Nat Prod Rep 24: 278-297.
5. De Carvalho EA, Andrade PP, Silva NH, Pereira EC, Figueiredo RC (2005): Effect of usnic acid from the lichen Cladonia substellata on Trypanosoma cruzi in vitro: An ultrastructural study. Micron 36: 155-161.
6. Fazio AT, Adler MT, Bertoni MD, Sepulveda CS, Damonte EB, Maier MS (2007): Lichen secondary metabolites from the cultured lichen mycobionts of Teloschistes chrysophthalmus and Ramalina celastri and their antiviral activities. Z Naturforsch C 62: 543-549.
7. Garcia-Navarro X, Barnadas MA, Dalmau J, Coll P, Gurgui M, Alomar A (2008): Mycobacterium abscessus infection secondary to mesotherapy. Clin Exp Dermatol 5: 658-659.
8. Han D, Matsumaru K, Rettori D, Kaplowitz N (2004): Usnic acidinduced necrosis of cultured mouse hepatocytes: Inhibition of mitochondrial function and oxidative stress. Biochem Pharmacol. 67: 439-451.
9. Hsieh HC, Lu PL, Chen TC, Chang K, Chen YH (2008): Mycobacterium chelonae empyema in an immunocompetent patient. J Med Microbiol 57: 664-667.
10. Ingólfsdóttir K, Chung GA, Skulason VG, Gissurarson SR, Vilhelmsdottir M (1998): Antimycobacterial activity of lichen metabolites in vitro. Eur J Pharm; 6: 141-144
11. Ingólfsdóttir K (2002): Usnic acid. Phytochemistry 61: 729-736.
12. Jarzembowski JA, Young MB (2008): Nontuberculous mycobacterial infections. Arch Pathol Lab Med 8: 1333-1341 Mata R, Morales I, Perez O, Rivero-Cruz I, Acevedo L, Enriquez-
13. Mata R, Morales I, Perez O, Rivero-Cruz I, Acevedo L, Enriquez-Mendoza I, Bye R, Franzblau S, Timmermann B (2004): Antimycobacterial compounds from Piper sanctum. J Nat Prod 67: 1961-1968.
14. Okunade AL, Elvin-Lewis MP, Lewis WH (2004): Natural antimycobacterial metabolites: Current status. Phytochemistry 65: 1017-1032.
15. Palomino JC, Martin A, Camacho M, Guerra H, Swings J, Portaels F (2002): Resazurin microtiter assay plate: Simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother 46: 2720-2722.
16. Pauli GF, Case RJ, Inui T, Wang Y, Cho S, Fischer NH, Franzblau SG (2005): New perspectives on natural products in TB drug research. Life Sci 78: 485-494.
17. Reddy VC, Prasad CE, Aparna S, Gokhale S, Anjeneyulu (2008): A study of mycobacterial species causing lymphadenitis. Southeast Asian J Trop Med Public Health 39: 130-135.
18. Rojas R, Caviedes L, Aponte JC, Vaisberg AJ, Lewis WH, Lamas G, Sarasara C, Gilman RH, Hammond GB (2006): Aegicerin, the first oleanane triterpene with wide-ranging antimycobacterial activity, isolated from Clavija procera. J Nat Prod 69: 845-846.
19. Shibata S, Ukita T, Tamura T, Miura Y (1948): Relation between chemical constitutions and antibacterial effects of usnic acid and derivates. Jap Med J 1: 152-155.
20. Stavri M, Mathew KT, Bucar F, Gibbons S (2003): Pangelin, an antimycobacterial coumarin from Ducrosia anethifolia. Planta Med 69: 956-959.
21. Stoll A, Brack A, Renz J (1950): The effect of lichenic substances on the tubercle bacillus and certain other microorganisms; seventh article on antibacterial substances. Schweiz Z Pathol Bakteriol 13: 729-751.
22. Vijayakumar CS, Viswanathan S, Reddy MK, Parvathavarthini S, Kundu AB, Sukumar E (2000): Anti-inflammatory activity of (+)-usnic acid. Fitoterapia 71: 564-566.
23. WHO REPORT (2008): Global tuberculosis control-survellance, planning, financing. Geneve, WHO/HTM/TB.2008. 393: 15-45.