Aggregation and cytotoxic properties towards cultured cerebrovascular cells of Dutch-mutated Aβ40 (DAβ1-40) are modulated by sulfate moieties of heparin

Neuroscience Research

Volumn 66, Issue 4, 2010, Pages 380-389

  Timmer, Nienke M ^a   Schirris, Tom J J ^a   Bruinsma, Ilona B ^a   Otte Höller, Irene ^a   van Kuppevelt, Toin H ^b   de Waal, Robert M W ^a   Verbeek, Marcel M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Alzheimer's disease; Amyloid beta; Cerebrovascular cells; Glycosaminoglycans; Heparan sulfate proteoglycans

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; ANTIBODY; CHONDROITIN SULFATE; DEXTRAN SULFATE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN DERIVATIVE; THIOFLAVINE;

AGED; ALZHEIMER DISEASE; AMYLOIDOSIS; ARTICLE; AUTOPSY; BRAIN CELL; CELL VIABILITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; OCCIPITAL LOBE; PRIORITY JOURNAL;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CELL DEATH; CELLS, CULTURED; CEREBRAL AMYLOID ANGIOPATHY; CHONDROITIN SULFATES; FEMALE; HEPARIN; HEPARITIN SULFATE; HUMANS; MUTATION; OCCIPITAL LOBE; PEPTIDE FRAGMENTS; PERICYTES;

EID: 77249092622     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2009.12.012     Document Type: Article

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