IL-7 receptor is expressed on adult pre-B-cell acute lymphoblastic leukemia and other B-cell derived neoplasms and correlates with expression of proliferation and survival markers

Cytokine

Volumn 50, Issue 1, 2010, Pages 58-68

  Sasson, Sarah C ^a,b   Smith, Sandy ^c   Seddiki, Nabila ^a   Zaunders, John J ^b   Bryant, Adam ^b   Koelsch, Kersten K ^d   Weatherall, Christopher ^d   Munier, Mee Ling ^a,b   McGinley, Ciara ^a   Yeung, Julie ^b   Mulligan, Stephen P ^e   Moore, John ^b   Cooper, David A ^a,b,d   Milliken, Sam ^b   Kelleher, Anthony D ^a,b,d  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ST VINCENT S HOSPITAL   (Australia)

^c Immunopathology Laboratory   (Australia)

^d ST VINCENT S HOSPITAL   (Australia)

^e ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

CD127; CD132; IL 7; IL 7R; pre B ALL

Indexed keywords

B CELL ACTIVATING FACTOR; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR GAMMA; INTERLEUKIN 21; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; KI 67 ANTIGEN; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; B CELL LEUKEMIA; B CELL LYMPHOMA; BONE MARROW CELL; CANCER SURVIVAL; CARCINOGENESIS; CELL LINEAGE; CELL PROLIFERATION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; NONHODGKIN LYMPHOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ADULT; AGED; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PROLIFERATION; CRYOPRESERVATION; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; KI-67 ANTIGEN; MALE; MIDDLE AGED; PHENOTYPE; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, INTERLEUKIN-7; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; T-LYMPHOCYTES; TUMOR MARKERS, BIOLOGICAL;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77249090165     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2009.12.001     Document Type: Article

References (52)

1. Sakata T., Iwagami S., Tsuruta Y., Teraoka H., Tatsumi Y., Kita Y., et al. Constitutive expression of interleukin-7 mRNA and production of IL-7 by a cloned murine thymic stromal cell line. J Leukoc Biol 48 (1990) 205-212
2. Gutierrez-Ramos J.C., Olsson C., and Palacios R. Interleukin (IL1 to IL7) gene expression in fetal liver and bone marrow stromal clones: cytokine-mediated positive and negative regulation. Exp Hematol 20 (1992) 986-990
3. Wiles M.V., Ruiz P., and Imhof B.A. Interleukin-7 expression during mouse thymus development. Eur J Immunol 22 (1992) 1037-1042
4. Namen A.E., Schmierer A.E., March C.J., Overell R.W., Park L.S., Urdal D.L., et al. B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors. J Exp Med 167 (1988) 988-1002
5. von Freeden-Jeffry U., Vieira P., Lucian L.A., McNeil T., Burdach S.E., and Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 181 (1995) 1519-1526
6. Goodwin R.G., Friend D., Ziegler S.F., Jerzy R., Falk B.A., Gimpel S., et al. Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. Cell 60 (1990) 941-951
7. Noguchi M., Nakamura Y., Russell S.M., Ziegler S.F., Tsang M., Cao X., et al. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science 262 (1993) 1877-1880
8. Sudo T., Nishikawa S., Ohno N., Akiyama N., Tamakoshi M., and Yoshida H. Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc Natl Acad Sci USA 90 (1993) 9125-9129
9. Ryan D.H., Nuccie B.L., Ritterman I., Liesveld J.L., Abboud C.N., and Insel R.A. Expression of interleukin-7 receptor by lineage-negative human bone marrow progenitors with enhanced lymphoid proliferative potential and B-lineage differentiation capacity. Blood 89 (1997) 929-940
10. Seddiki N., Santner-Nanan B., Martinson J., Zaunders J., Sasson S., Landay A., et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 203 (2006) 1693-1700
11. Liu W., Putnam A.L., Xu-Yu Z., Szot G.L., Lee M.R., Zhu S., et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4(+) T reg cells. J Exp Med 203 (2006) 1701-1711
12. Rethi B., Fluur C., Atlas A., Krzyzowska M., Mowafi F., Grutzmeier S., et al. Loss of IL-7Ralpha is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients. AIDS 19 (2005) 2077-2086
13. Peschon J.J., Morrissey P.J., Grabstein K.H., Ramsdell F.J., Maraskovsky E., Gliniak B.C., et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 180 (1994) 1955-1960
14. Puel A., Ziegler S.F., Buckley R.H., and Leonard W.J. Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet 20 (1998) 394-397
15. Sasson S.C., Zaunders J.J., Zanetti G., King E.M., Merlin K.M., Smith D.E., et al. Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection. J Infect Dis 193 (2006) 505-514
16. Fry T.J., Moniuszko M., Creekmore S., Donohue S.J., Douek D.C., Giardina S., et al. IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates. Blood 101 (2003) 2294-2299
17. Park J.H., Yu Q., Erman B., Appelbaum J.S., Montoya-Durango D., Grimes H.L., et al. Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 21 (2004) 289-302
18. Vranjkovic A., Crawley A.M., Gee K., Kumar A., and Angel J.B. IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells. Int Immunol 19 (2007) 1329-1339
19. von Freeden-Jeffry U., Solvason N., Howard M., and Murray R. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 7 (1997) 147-154
20. Welch P.A., Namen A.E., Goodwin R.G., Armitage R., and Cooper M.D. Human IL-7: a novel T cell growth factor. J Immunol 143 (1989) 3562-3567
21. Schluns K.S., Kieper W.C., Jameson S.C., and Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 1 (2000) 426-432
22. Soares M.V., Borthwick N.J., Maini M.K., Janossy G., Salmon M., and Akbar A.N. IL-7-dependent extrathymic expansion of CD45RA+ T cells enables preservation of a naive repertoire. J Immunol 161 (1998) 5909-5917
23. Webb L.M., Foxwell B.M., and Feldmann M. Putative role for interleukin-7 in the maintenance of the recirculating naive CD4+ T-cell pool. Immunology 98 (1999) 400-405
24. Tan J.T., Dudl E., LeRoy E., Murray R., Sprent J., Weinberg K.I., et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci USA 98 (2001) 8732-8737
25. Seddon BaZ R. TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induces expansion of naive T cells. J Immunol (2002) 3752-3759
26. Roifman C.M., Zhang J., Chitayat D., and Sharfe N. A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency. Blood 96 (2000) 2803-2807
27. Dalloul A., Laroche L., Bagot M., Mossalayi M.D., Fourcade C., Thacker D.J., et al. Interleukin-7 is a growth factor for Sezary lymphoma cells. J Clin Invest 90 (1992) 1054-1060
28. Frishman J., Long B., Knospe W., Gregory S., and Plate J. Genes for interleukin 7 are transcribed in leukemic cell subsets of individuals with chronic lymphocytic leukemia. J Exp Med 177 (1993) 955-964
29. Rich B.E., Campos-Torres J., Tepper R.I., Moreadith R.W., and Leder P. Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice. J Exp Med 177 (1993) 305-316
30. Benjamin D., Sharma V., Knobloch T.J., Armitage R.J., Dayton M.A., and Goodwin R.G. B cell IL-7. Human B cell lines constitutively secrete IL-7 and express IL-7 receptors. J Immunol 152 (1994) 4749-4757
31. Touw I., Pouwels K., van Agthoven T., van Gurp R., Budel L., Hoogerbrugge H., et al. Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia. Blood 75 (1990) 2097-2101
32. De Waele M., Renmans W., Vander Gucht K., Jochmans K., Schots R., Otten J., et al. Growth factor receptor profile of CD34+ cells in AML and B-lineage ALL and in their normal bone marrow counterparts. Eur J Haematol 66 (2001) 178-187
33. Nishii K., Katayama N., Miwa H., Shikami M., Masuya M., Shiku H., et al. Survival of human leukaemic B-cell precursors is supported by stromal cells and cytokines: association with the expression of bcl-2 protein. Br J Haematol 105 (1999) 701-710
34. Mocroft A., Katlama C., Johnson A.M., Pradier C., Antunes F., Mulcahy F., et al. AIDS across Europe, 1994-98: the EuroSIDA study. Lancet 356 (2000) 291-296
35. Zaunders J.J., Moutouh-de Parseval L., Kitada S., Reed J.C., Rought S., Genini D., et al. Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2. J Infect Dis 187 (2003) 1735-1747
36. Napolitano L.A., Grant R.M., Deeks S.G., Schmidt D., De Rosa S.C., Herzenberg L.A., et al. Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med 7 (2001) 73-79
37. Fry T.J., Connick E., Falloon J., Lederman M.M., Liewehr D.J., Spritzler J., et al. A potential role for interleukin-7 in T-cell homeostasis. Blood 97 (2001) 2983-2990
38. Rosenberg S.A., Sportes C., Ahmadzadeh M., Fry T.J., Ngo L.T., Schwarz S.L., et al. IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells. J Immunother 29 (2006) 313-319
39. Sereti I., Dunham R.M., Spritzler J., Aga E., Proschan M.A., Medvik K., et al. IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood 113 (2009) 6304-6314
40. Malaspina A., Moir S., Ho J., Wang W., Howell M.L., O'Shea M.A., et al. Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: correlation with increased IL-7. Proc Natl Acad Sci USA 103 (2006) 2262-2267
41. Malaspina A., Moir S., Chaitt D.G., Rehm C.A., Kottilil S., Falloon J., et al. Idiopathic CD4+ T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7. Blood (2006)
42. Colle J.H., Moreau J.L., Fontanet A., Lambotte O., Joussemet M., Jacod S., et al. Regulatory dysfunction of the interleukin-7 receptor in CD4 and CD8 lymphocytes from HIV-infected patients - effects of antiretroviral therapy. J Acquir Immune Defic Syndr 42 (2006) 277-285
43. Pui C.H., Robison L.L., and Look A.T. Acute lymphoblastic leukaemia. Lancet 371 (2008) 1030-1043
44. Mackay F., and Tangye S.G. The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers. Curr Opin Pharmacol 4 (2004) 347-354
45. Haiat S., Billard C., Quiney C., Ajchenbaum-Cymbalista F., and Kolb J.P. Role of BAFF and APRIL in human B-cell chronic lymphocytic leukaemia. Immunology 118 (2006) 281-292
46. Kern C., Cornuel J.F., Billard C., Tang R., Rouillard D., Stenou V., et al. Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 103 (2004) 679-688
47. Kebelmann-Betzing C., Korner G., Badiali L., Buchwald D., Moricke A., Korte A., et al. Characterization of cytokine, growth factor receptor, costimulatory and adhesion molecule expression patterns of bone marrow blasts in relapsed childhood B cell precursor all. Cytokine 13 (2001) 39-50
48. Wu A.M., Till J.E., Siminovitch L., and McCulloch E.A. Cytological evidence for a relationship between normal hematopoietic colony-forming cells and cells of the lymphoid system. J Exp Med 127 (1968) 455-464
49. Voorzanger N., Touitou R., Garcia E., Delecluse H.J., Rousset F., Joab I., et al. Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors. Cancer Res 56 (1996) 5499-5505
50. Hannig H., Matz-Rensing K., Kuhn E.M., Stahl-Hennig C., Kaup F.J., Hunsmann G., et al. Cytokine gene transcription in simian immunodeficiency virus and human immunodeficiency virus-associated non-Hodgkin lymphomas. AIDS Res Hum Retroviruses 13 (1997) 1589-1596
51. Stachel D., Albert M., Meilbeck R., Kreutzer B., Haas R.J., and Schmid I. Bone marrow Th2 cytokine expression as predictor for relapse in childhood acute lymphoblastic leukemia (ALL). Eur J Med Res 11 (2006) 102-113
52. Sasson S.C., Zaunders J.J., and Kelleher A.D. The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostasis and the challenges facing its utilization as a novel therapy. Curr Drug Targets 7 (2006) 1571-1582