Neonatal mucosal immunization with a non-living, non-genetically modified Lactococcus lactis vaccine carrier induces systemic and local Th1-type immunity and protects against lethal bacterial infection

Mucosal Immunology

Volumn 3, Issue 2, 2010, Pages 159-171

  Ramirez, K ^a   Ditamo, Y ^a   Rodriguez, L ^a   Picking, W L ^b   Van Roosmalen, M L ^c   Leenhouts, K ^c   Pasetti, M F ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c Mucosis BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BACTERIAL VACCINE; DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LACTOCOCCUS LACTIS VACCINE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; BACTERIAL INFECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DRUG EFFICACY; DRUG SAFETY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE REACTION; MOUSE; MUCOSA; NEWBORN; NONHUMAN; PLAGUE; PRIORITY JOURNAL; TH1 CELL; YERSINIA PESTIS;

EID: 77249086689     PISSN: 19330219     EISSN: None     Source Type: Journal    
DOI: 10.1038/mi.2009.131     Document Type: Article

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