Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: Direct observation of formaldehyde

ChemBioChem

Volumn 11, Issue 4, 2010, Pages 506-510

  Hopkinson, Richard J ^a   Hamed, Refaat B ^a   Rose, Nathan R ^a   Claridge, Timothy D W ^a   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Enzyme catalysis; Formaldehyde; Histone demethylases; NMR spectroscopy; Transcriptional regulation

Indexed keywords

2 OXOGLUTARIC ACID; ENZYME; FORMALDEHYDE; HISTONE DEMETHYLASE; UNCLASSIFIED DRUG;

ARTICLE; DECARBOXYLATION; DEMETHYLATION; ENZYME ACTIVITY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ESCHERICHIA COLI; FORMALDEHYDE; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; KETOGLUTARIC ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES;

EID: 77149164783     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900713     Document Type: Article

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