PH-dependent pKa values in proteins-a theoretical analysis of protonation energies with practical consequences for enzymatic reactions

Journal of Physical Chemistry B

Volumn 114, Issue 5, 2010, Pages 1994-2003

  Bombarda, Elisa ^a   Ullmann, G Matthias ^a  

^a UNIVERSITÄT BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSTS; ENZYMES; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FREE ENERGY; ORGANIC ACIDS; TITRATION;

ABSOLUTE TEMPERATURES; AMINO ACID RESIDUES; BIOCHEMICAL RESEARCH; ELECTROSTATIC INTERACTIONS; ENZYMATIC MECHANISMS; ENZYMATIC REACTION; ENZYME CATALYSIS; FREE ENERGY CHANGE; FTIR; GAS CONSTANTS; LIMITING CASE; LINEAR RELATIONSHIPS; NONLINEAR DEPENDENCE; PH DEPENDENCE; PH-DEPENDENT; PROTONATION ENERGY; SIGMOIDAL SHAPE; SIMPLE MODEL; TITRATION CURVES; WEAK INTERACTIONS; WIDE PH RANGE;

PROTONATION;

PLASTOCYANIN; PROTON; RIBONUCLEASE T1;

ARTICLE; BIOCATALYSIS; CHEMICAL MODEL; CHEMISTRY; KINETICS; PH; THERMODYNAMICS;

BIOCATALYSIS; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, CHEMICAL; PLASTOCYANIN; PROTONS; RIBONUCLEASE T1; THERMODYNAMICS;

EID: 77149161107     PISSN: 15206106     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp908926w     Document Type: Article

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