Pharmacokinetics and disposition of CS-8958, a long-acting prodrug of the novel neuraminidase inhibitor laninamivir in rats

Xenobiotica

Volumn 40, Issue 3, 2010, Pages 207-216

  Koyama, K ^a   Takahashi, M ^a   Nakai, N ^a   Takakusa, H ^a   Murai, T ^a   Hoshi, M ^a   Yamamura, N ^a   Kobayashi, N ^a   Okazaki, O ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

CS 8958; Laninamivir; Long acting neuraminidase inhibitor; Pharmacokinetics

Indexed keywords

CARBON 14; CS 8958; DRUG METABOLITE; LANINAMIVIR; R 125489; SIALIDASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG ABSORPTION; DRUG DISPOSITION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG RETENTION; ISOTOPE LABELING; LUNG; MALE; NONHUMAN; RADIOACTIVITY; RAT; TISSUE DISTRIBUTION; TRACHEA; URINE;

ANIMALS; ANTIVIRAL AGENTS; BILE; CHROMATOGRAPHY, THIN LAYER; ENZYME INHIBITORS; FECES; MALE; NEURAMINIDASE; PRODRUGS; RADIOACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TISSUE DISTRIBUTION; TISSUE EXTRACTS; ZANAMIVIR;

RATTUS;

EID: 77149157529     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498250903447691     Document Type: Article

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