Expression of VEGF receptors VEFGR-1 and VEGFR-2, angiopoietin receptors Tie-1 and Tie-2 in chorionic villi tree during early pregnancy

Folia Histochemica et Cytobiologica

Volumn 47, Issue 3, 2009, Pages 435-445

  Demir, Ramazan ^a  

^a AKDENIZ UNIVERSITY   (Turkey)

Author keywords

Angiogenesis; Early pregnancy; Haemangiogenic cells; Human placenta; Vasculogenesis

Indexed keywords

ANGIOPOIETIN RECEPTOR; TIE 1 RECEPTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANTIBODY LABELING; ARTICLE; BLOOD VESSEL; CHORION VILLUS; ELECTRON MICROSCOPY; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; PLACENTA; PLACENTA VILLUS; PROTEIN EXPRESSION; ULTRASTRUCTURE;

EID: 77149157526     PISSN: 02398508     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10042-009-0100-5     Document Type: Article

References (60)

1. Ahmed A, Dunk C, Ahmad S and Khaliq A. Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen - a review. Placenta 2000; 21: 16-24.
2. Benirschke K, Kaufmann P. Pathology of the Human Placenta. Springer, New York, 2000.
3. Brockelsby JC, Anthony FW, Johnson IR and Baker PN. The effects of vascular endothelial growth factor on endothelial cells: A potential role in preeclampsia. Am. J. Obstet. Gynecol. 2000;182: 176-83.
4. Cervar M, Blaschitz A, Dohr G and Desoye G. Paracrine regulation of distinct trophoblast functions in vitro by placental macrophages. Cell Tissue Res. 1999; 295: 297-305.
5. Charnock-Jones DS, Kaufmann P and Mayhew TM. Aspects of human fetoplacental vasculogenesis and angiogenesis. I. Molecular regulation. Placenta 2004; 25: 103-13.
6. Cheung CY. Vascular endothelial growth factor: possible role in fetal development and placental function. J Soc Gynecol Invest. 1997; 4.169-77.
7. Clark DE, Smith SK, Licence D, Evans AL and Charnock-Jones DS. Comparison of expression patterns for placenta growth factor, vascular endothelial growth factor (VEGF), VEGF-B and VEGF-C in the human placenta throughout gestation. J Endocrinol. 1998; 159: 459-67.
8. Cogle CR and Scott EW. The hemangioblast: cradle to clinic. Exp Hematol. 2004; 32: 885-890.
9. Cooper JC, Sharkey AM, McLaren J, Charnock-Jones DS and Smith SK. Localization of vascular endothelial growth factor and its receptor, flt, in human placenta and decidua by immunohistochemistry. J Reprod Fertil . 1995;105: 205-13.
10. Demir R. Ultrastructure of the epithelium of the chorionic villi of the human placenta. Acta Anat (Basel). 1980; 106: 18-29.
11. Demir R, Demir N, Ustunel I, Erbengi T, Trak I and Kaufmann P. The fine structure of normal and ectopic (tubal) human placental villi as revealed by scanning and transmission electron microscopy. Zentralbl Pathol. 1995; 140: 427-42.
12. Demir R and Erbengi T. Some new findings about Hofbauer cells in the chorionic villi of the human placenta. Acta Anat (Basel).1984;119: 18-26.
13. Demir R, Kaufmann P, Castellucci M, Erbengi T and Kotowski A. Fetal vasculogenesis and angiogenesis in human placental villi. Acta Anat (Basel) 1989; 136: 190-203.
14. Demir R, Kayisli UA, Cayli S and Huppertz B. Sequential Steps During Vasculogenesis and Angiogenesis in the Very Early Human Placenta. Placenta 2006; 27:535-39.
15. Demir R, Kayisli UA, Celik-Ozenci C, Korgun ET, Demir-Weusten AY and Arici A. Structural differentiation of human uterine luminal and glandular epithelium during early pregnancy: an ultrastructural and immunohistochemical study. Placenta 2002; 23: 672-84.
16. Demir R, Kayisli UA, Seval Y, Celik-Ozenci C, Korgun ET, Demir-Weusten AY and Huppertz B. Sequential expression of VEGF and its receptors in human placental villi during very early pregnancy: differences between placental vasculogenesis and angiogenesis. Placenta 2004; 25:560-72.
17. Demir R, Kosanke G, Kohnen G, Kertschanska S and Kaufmann P. Classification of human placental stem villi: review of structural and functional aspects. Microsc Res Tech. 1997; 38: 29-41.
18. Demir R, Acar G, Tanriover G, Seval Y, Kayisli UA, Agar A. Effects of excess vitamin B6 intake on cerebral cortex neurons in rat: an ultrastructural study. Folia Histochem Cytobiol. 2005; 43(3):143-50.
19. Demir R, Seval Y, Huppertz B. Vasculogenesis and angiogenesis in the early human placenta. Acta Histochem. 2007;109 (4):257-65.
20. Dunk C and Ahmed A. Expression of VEGF-C and activation of its receptors VEGFR-2 and VEGFR-3 in trophoblast. Histol Histopathol. 2001; 16: 359-75.
21. Dvorak HF, Brown LF, Detmar M and Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol. 1995; 146: 1029-39.
22. El-Salahy EM, Ahmed MI, El-Gharieb Aand Tawfik H. New scope in angiogenesis: Role of vascular endothelial growth factor (VEGF), NO, lipid peroxidation, and vitamin E in the pathophysiology of pre-eclampsia among Egyptian females. Clin Biochem. 2001; 34: 323-29.
23. Ferrara N. Vascular endothelial growth factor and the regulation of angiogenesis. Recent Prog Horm Res 2000; 55: 15-35.
24. Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev. 2004; 25 581-611.
25. Fong GH, Rossant J, Gertsenstein M and Breitman ML. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995; 376: 66-70.
26. Fong GH, Zhang L, Bryce DM and Peng J. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development 1999;126: 3015-25.
27. Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997;277: 48-50.
28. Hanahan D and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-64.
29. Helske S, Vourela P, Carpén O, Horning C, Weich H and Halmesmäki E. Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies. Mol. Hum. Reprod. 2001; 7: 205-10.
30. Hiratsuka S, Nakao K, Nakamura K, Katsuki M, Maru Y and Shibuya M. Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice. Mol Cell Biol. 2005; 25: 346-54.
31. Gu B, Alexander JS, Gu Y, Zhang Y, Lewis DF and Wang Y. Expression of lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1) in the human placenta. Lymphat Res Biol. 2006; 4: 11-7.
32. Joukov V, Pajusola K, Kaipainen A, et al. A novel vascular endothelial growth factor, VEGF-C, is the ligand for the Flt-4 receptor tyrosine kinase (VEGFR-3) EMBO J. 1996; 15: 290-98.
33. Kaufmann P, Mayhew TM and Charnock-Jones DS. Aspects of human fetoplacental vasculogenesis and angiogenesis. II. Changes during normal pregnancy. Placenta 2004; 25: 114-26.
34. Kayisli UA, Cayli S, Seval Y, Tertemiz F, Huppertz B and Demir R. Spatial and temporal distribution of Tie-1 and Tie-2 during very early development of the human placenta. Placenta 2006; 27:648-59.
35. Kingdom J, Huppertz B, Seaward G and Kaufmann P. Development of the placental villous tree and its consequences for fetal growth. Eur J Obstet Gynecol Reprod Biol. 2000; 92: 35-43.
36. Kumazaki K, Nakayama M, Suehara N and Yoshinao W. Expression of vascular endothelial growth factor, placental growth factor, and their receptors flt-1 and KDR in human placenta under pathologic conditions. Hum. Pathol. 2002; 33: 1069-77.
37. Leach L, Babawale MO, Anderson M and Lammiman M. Vasculogenesis, angiogenesis and the molecular organisation of endothelial junctions in the early human placenta. J Vasc Res. 2002; 39: 246-59.
38. Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997; 277: 55-60.
39. Mayhew TM, Charnock-Jones DS and Kaufmann P. Aspects of human fetoplacental vasculogenesis and angiogenesis. III. Changes in complicated pregnancies. Placenta 2004; 25: 127-39.
40. Millauer B, Wizigmann-Voos S, Schnurch H, et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 1993;72: 835-46.
41. O'Rahilly R and Tucker JA. The early development of the larynx in staged human embryos. I. Embryos of the first five weeks (to stage 15). Ann Otol Rhinol Laryngol. 1973; 82:1-27.
42. Pardanaud L, Yassine F and Dieterlen-Lievre F. Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny. Development 1989;105: 473-85.
43. Park JE, Chen HH, Winer J, Houck KA and Ferrara N. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem. 1994; 269: 25646-54.
44. Redman CW and Sargent IL. The pathogenesis of pre-eclampsia. Gynecol. Obstet. Fertil. 29, 518-522.
45. Sato TN, Tozawa Y, Deutsch U, et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995; 376:70-74.
46. Sgambati E, Marini M, Zappoli Thyrion GD, et al. VEGF expression in the placenta from pregnancies complicated by hypertensive disorders. BJOG Int J Obstet Gynecol. 2004; 111: 564-70.
47. Seval Y, Korgun ET, Demir R. Hofbauer cells in early human placenta: possible implications in vasculogenesis and angiogenesis. Placenta. 2007;28 (8-9):841-5.
48. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS and Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219: 983-85.
49. Shalaby F, Rossant J, Yamaguchi TP, et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 1995;376: 62-6.
50. Shore VH, Wang TH, Wang CL, Torry RJ, Caudle MR and Torry DS. Vascular endothelial growth factor, placenta growth factor and their receptors in isolated human trophoblast. Placenta 1997; 18:657-65.
51. Suri C, Jones PF, Patan S, et al. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 1996; 87: 1171-80.
52. Szukiewicz D, Szewczyk G, Watroba M, Kurowska E and Maslinski S. Isolated placental vessel response to vascular endothelial growth factor and placenta growth factor in normal and growth-restricted pregnancy. Gynecol Obstet Invest. 2005; 59: 102-7.
53. Tammela T, Enholm B, Alitalo K and Paavonen K. The biology of vascular endothelial growth factors. Cardiovasc Res. 2005; 65: 550-63.
54. Terman BI, Dougher-Vermazen M, Carrion ME, et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun. 1992; 187: 1579-86.
55. Torry DS and Torry RJ. Angiogenesis and the expression of vascular endothelial growth factor in endometrium and placenta. Am J Reprod Immunol. 1997;37:21-9.
56. Tsatsaris V, Goffin F, Munaut C, et al. Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences. J Clin Endocrinol Metab. 2003; 88: 5555-63.
57. Tsokos M, Longauer F, Kardosova V, Gavel A, Anders S and Schulz F. Maternal death in pregnancy from HELLP syndrome. Areport of three medico-legal autopsy cases with special reference to distinctive histopathological alterations. Int J Legal Med. 2002;116: 50-3.
58. Vuckovic M, Ponting J, Terman BI, Niketic V, Seif MW and Kumar S. Expression of the vascular endothelial growth factor receptor, KDR, in human placenta. J Anat. 1996; 188 (Pt 2): 361-66.
59. Vuorela P, Hatva E, Lymboussaki A, et al. Expression of vascular endothelial growth factor and placenta growth factor in human placenta. Biol Reprod. 1997; 56: 489-94.
60. Zhou Y, McMaster M, Woo K, et al. Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am. J. Pathol. 2002; 160: 1405-23.