Reduction of percutaneous absorption of toxic chemicals by dendrimers

Cutaneous and Ocular Toxicology

Volumn 29, Issue 1, 2010, Pages 34-40

  Moghimi, Hamid R ^a   Varshochian, Reyhaneh ^a   Kobarfard, Farzad ^a   Erfan, Mohammad ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Absorption retardation; Cutaneous hazards; PAMAM dendrimer; Polyamidoamine dendrimer; Skin protection

Indexed keywords

FURFURAL; POLYAMIDOAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; MALE; NONHUMAN; RAT; SKIN ABSORPTION; SKIN PERMEABILITY; SKIN SURFACE; SKIN TOXICITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; DENDRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; FURALDEHYDE; KINETICS; MALE; PERMEABILITY; PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION;

RATTUS;

EID: 77149149027     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.3109/15569520903429200     Document Type: Article

References (33)

1. O'Flaherty EJ. Absorption, distribution, and elimination of toxic agents. In:Williams PL, James RC, Roberts SM, eds. Principles of Toxicology: Environmental and Industrial Applications. 2nd ed; New York: John Wiley and Sons. 2000:35-55.
2. Zhai H, Maibach HI. Barrier creams. In:Zhai H, Maibach HI, eds. Dermatotoxicology. 6th ed; Boca Raton, FL: CRC Press. 2004:509-516
3. Platoff GE, Baskin SI, Madsen JM. Military personnel part III-chemical threats. In:Greenberg MI, Hamilton RJ, Phillips SD, McCluskey GJ, eds. Occupational, Industrial and Environmental Toxicology. 2nd ed; Philadelphia, PA: Mosby. 2003:258-273
4. Aaron CK. Organophosphates and carbamates. In:Ford MD, Delaney KA, Ling LJ, Erickson T, eds. Clinical Toxicology. Philadelphia, PA: W.B. Saunders Company. 2001:819-828
5. Hatch KL, Maibach HI. Textile chemical finish dermatitis. Contact Dermatitis 1986;14:1-13.
6. Mathias CG.Prevention of occupational contact dermatitis. J Am Acad Dermatol 1990;23:742-748
7. Davidson CL. Occupational contact dermatitis of the upper extremity. Occup Med 1994;9(1):59-74.
8. Berndt U, Gabard B, Schliemann-Willers S, Wigger-Alberti W, Zitterbart D, Elsner P. Integrated skin protection from workplace irritants: a new model for efficacy assessment. Exog Dermatol 2002;1:45-48
9. Berndt U, Wigger-Alberti W, Gabard B, Elsner P. Efficacy of a barrier cream and its vehicle as protective measures against occupational irritant contact dermatitis. Contact Dermatitis 2000;42(2):77-80.
10. Korinth G, Geh S, Schaller KH, Drexler H. In vitro evaluation of the efficacy of skin barrier creams and protective gloves on percutaneous absorption of industrial solvents. Int Arch Occup Environ Health 2003;76(5):382-386
11. Teichmann A, Jacobi U, Waibler E, Sterry W, Lademann J. An in vivo model to evaluate the efficacy of barrier creams on the level of skin penetration of chemicals. Contact Dermatitis 2006;54(1):5-13.
12. Moghimi HR, Shakerinejad A. Retardation effects of ?-cyclodextrin and polyethylene glycol on percutaneous absorption of nitroglycerin. Presented at: Sixth International Perspectives in Percutaneous Penetration Conference, Leiden, Germany, 1998:34.
13. Shakerinejad A. Reduction of percutaneous absorption of toxic compounds. PharmD Thesis, School of Pharmacy, Shahid Beheshti Medical University, Tehran, Iran, 1998:73.
14. Haeri A. Reduction of percutaneous absorption of chemicals through in-situ covalent bond formation. PharmD Thesis, School of Pharmacy, Shahid Beheshti Medical University, Tehran, Iran, 2006:106.
15. Gillies ER, Fréchet JM. Dendrimers and dendritic polymers in drug delivery. Drug Discov Today 2005;10(1):35-43.
16. Cloninger MJ. Biological application of dendrimers. Curr Opin Chem Biol 2002;6:742-748
17. Tomalia DA. Birth of new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Prog Polym Sci 2005;30:294-324.
18. D'Emanuele A, Attwood D. Dendrimer-drug interactions. Adv Drug Deliv Rev 2005;57:2147-2162
19. Milhem OM, Myles C, McKeown NB, Attwood D, D'Emanuele A. Polyamidoamine Starburst dendrimers as solubility enhancers. Int J Pharm 2000;197(1-2): 239-241
20. Kukowaska-Latallo JF, Bielinska AU, Johnson J, Spindler R, Tomalia DA, Baker JR Jr. Efficient transfer of genetic material into mammalian cells by using Starburst polyamidoamine dendrimers. Proc Natl Acad Sci U S A 1996;93(10): 4897-4902
21. Markatou E, Gionis V, Chryssikos GD, Hatziantoniou S, Georgopoulos A, Demetzos C. Molecular interaction between dimethoxycurcumin and PAMAM dendrimer carriers. Int J Pharm 2007;339:231-236
22. Gupta U, Agashe HB, Asthana A, Jain NK. Dendrimers: novel polymeric nanoarchitectures for solubility enhancement. Biomacromolecules 2006;7(3):649-658
23. Wang Z, Itoh Y, Hosaka Y, Kobayashi I, Nakano Y, Maeda I, et al. Mechanism of enhancement effect of dendrimer on transdermal drug permeation through polyhydroxyalkanoate matrix. J Biosci Bioeng 2003;96(6):537-540
24. Cromer JR, Wood SJ, Miller KA, Nguyen T, David SA. Functionalized dendrimers as endotoxin sponges. Bioorg Med Chem Lett 2005;15(5):1295-1298
25. Malik N, Wiwattanapatapee R, Klopsch R, Lorenz K, Frey H, Weener JW, et al. Relationship between structure and biocompatibility in vitro, and preliminary studies on biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Rel 2000;65:133-148
26. Grandjean P. Skin Penetration: Hazardous Chemicals at Work. London, UK: Taylor and Francis. 1990:25.
27. The Merck Index. 30th ed; Rahway, NJ: Merck and Co., Inc. 2001:4325.
28. Harbison RD, Garvey GJ. Aldehydes and ketones. In: Harbison RD, ed. Hamilton & Hardy's Industrial Toxicology. 5th ed; St. Louis, MO: Mosby. 1998:236-262
29. Harrison SM, Barry BW, Dugard PH. Effects of freezing on human skin permeability. J Pharm Pharmacol 1984;36:261-262
30. Wester RC, Maibach HI. Percutaneous absorption. In: Zhai H, Maibach HI, eds. Dermatotoxicology. 6th ed; Boca Raton, FL: CRC Press. 2004:85-103.
31. Williams AC, Barry BW. The enhancement index concept applied to terpene penetration enhancers for human skin and model lipophilic (oestradiol) and hydrophilic (5-fluorouracil) drugs. Int J Pharm 1991;74(2-3):57-168.
32. Barry BW. Dermatological Formulations, Percutaneous Absorption. New York: Marcel Dekker. 1983:66.
33. Cheng Y, Li Y, Wu Q, Zhang J, Xu T. Generation-dependent encapsulation/electrostatic attachment of phenobarbital molecules by poly (amido amine) dendrimers: evidence from 2D-NOESY investigations. Eur J Med Chem 2009;44(5):2219-2223