Upregulation of SEPT7 gene inhibits invasion of human glioma cells

Cancer Investigation

Volumn 28, Issue 3, 2010, Pages 248-258

  Xu, Song ^a   Jia, Zhi Fan ^a   Kang, Chunsheng ^a   Huang, Qiang ^a   Wang, Guangxiu ^a   Liu, Xiaozhi ^a   Zhou, Xuan ^a   Xu, Peng ^a   Pu, Peiyu ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Glioma; Invasion; SEPT7

Indexed keywords

ALPHA TUBULIN; GELATINASE A; GELATINASE B; MATRIGEL; MATRIX METALLOPROTEINASE 14; PROTEIN SEPT7; SEPTIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL STRAIN HEK293; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENETIC TRANSFECTION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LASER MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL LINE, TUMOR; CYTOSKELETAL PROTEINS; FEMALE; GLIOBLASTOMA; GLIOMA; GTP-BINDING PROTEINS; HUMANS; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFECTION; TUBULIN; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77149136471     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357900903179609     Document Type: Article

References (48)

1. Stupp, R.; Mason, W.P.; van Den Bent, M.J.; et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005, 352 (10), 987-996.
2. Hartwell, L.H. Genetic control of the cell division cycle in yeast IV genes controlling bud emergence and cytokinesis. Exp Cell Res 1971, 69 (2), 265-276.
3. Sirajuddin, M.; Farkasovsky, M.; Hauer, F.; et al. Structural insight into filament formation by mammalian septins. Nature 2007, 449 (7160), 311-315.
4. Low, C.; Macara, I.G. Structural analysis of Septin 2,6 and 7 complexes. J Biol Chem 281 (2006), 30697-30706.
5. Kremer, B.E.; Haystead, T.; Macara, I.G. Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Mol Biol Cell 2005, 16, 4648-4659.
6. Nagata, K.; Asano, T.; Nozawa, Y.; Inagaki, M. Biochemical and cell biological analyses of a mammalian septin complex SEPT7/9b/11. J Biol Chem 2004, 279, 55895-55904.
7. Xie, Y.; Vessey, J.P.; Konecna, A.; et al. The GTP-binding protein septin 7 is critical for dendrite branching and dendritic-spine morphology. Curr Biol 2007, 10, 1746-1751.
8. Hall, P.A.; Russell, S.E. The pathobiology of the septin gene family. J Pathol 2004, 204, 489-505.
9. Xie, Y.; Vessey, J.P.; Konecna, A.; et al. The GTP-binding protein Septin 7 is critical for dendrite branching and dendritic-spine morphology. Curr Biol 2007, 17, 1746-1751.
10. Zhu, M.; Wang, F.; Yan, F.; et al. Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem 2008, 283, 18916-18925.
11. Kremer, B.E.; Adang, L.A.; Macara, I.G. Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell 2007, 130, 837-850.
12. Hall, P.A.; Russell, S.E. The pathobiology of the septin gene family. J Pathol 2004, 204, 489-505.
13. Megonigal, M.D.; Rappaport, E.F.; Jones, D.H.; et al. t(11;22)(q23;q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes. Proc Natl Acad Sci USA 1998, 95, 6413-6418.
14. Ono, R.; Taki, T.; Taketani, T.; et al. SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24. Cancer Res 2002, 62, 333-337.
15. Osaka, M.; Rowley, J.D.; Zeleznik-Le, N.J. MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25). Proc Natl Acad Sci USA 1999, 96, 6428-6433.
16. Kojima, K.; Sakai, I.; Hasegawa, A.; et al. FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23). Leukemia 2004, 18, 998-1005.
17. Kalikin, L.M.; Sims, H.L.; Petty, E.M. Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors. Genomics 2000, 63, 165-172.
18. Montagna, C.; Lyu, M.S.; Hunter, K.; et al. The septin 9 (MSF) gene is amplified and over expressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines. Cancer Res 2003, 63, 2179-2187.
19. Burrows, J.F.; Chanduloy, S.; McIlhatton, M.A.; et al. Altered expression of the septin gene, SEPT9, in ovarian neoplasia. J Pathol 2003, 201, 581-588.
20. Sakai, K.; Kurimoto, M.; Tsugu, A.; et al. Expression of Nedd5, a mammalian septin, in human brain tumors. J Neurooncol 2002, 57, 169-177.
21. Kim, D.S.; Hubbard, S.L.; Peraud, A.; et al. Analysis of mammalian septin expression in human malignant brain tumours. Neoplasia 2004, 6, 168-178.
22. Scott, M.; Hyland, P.; McGregor, G.; et al. Multimodality expression profiling shows SEPT9 to be over-expressed in a wide range of human tumours. Oncogene 2005, 24, 4688-4700.
23. Kinoshita, A.; Kinoshita, M.; Akiyama, H.; et al. Identification of septins in neurofibrillary tangles in Alzheimer's disease. Am J Pathol 1998, 153, 1551-1560.
24. Cheon, M.S.; Fountoulakis, M.; Dierssen, M.; Ferreres, J.C.; Lubec, G. Expression profiles of proteins in fetal brain with Down syndrome. J Neural Transm Suppl 2001, 61, 311-319.
25. Engidawork, E.; Gulesserian, T.; Fountoulakis, M.; Lubec, G. Aberrant protein expression in cerebral cortex of fetus with Down syndrome. Neuroscience 2003, 122, 145-154.
26. Ihara, M.; Tomimoto, H.; Kitayama, H.; et al. Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. J Biol Chem 2003, 278, 24095-24102.
27. Huang, H.; Colella, S.; Kurrer, M.; et al. Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays. Cancer Res 2000, 60, 6868-6874.
28. Nagata, T.; Takahashi, Y.; Asai, S.; et al. The high level of SEPT7/hCDC10 gene expression in neuroblastoma may be associated with favorable characteristics of the tumor. J Surg Res 2000, 92, 267-275.
29. Hall, P.A.; Jung, K.; Hillan, K.J.; Russell, S.E. Expression profiling the human septin gene family. J Pathol 2005, 206, 269-278.
30. Jiang, R.C.; Pu, P.Y.; shen, C.H.; et al. Preliminary study on cancer-related gene expression profiles in 63 cases of gliomas by cDNA array. Chin J Neurosurg 2004, 1, 21-24.
31. Jia, Z.F.; Pu, P.Y.; Kang, C.S.; et al. Study on the expression of SEPT7/hCDC10 in astrocytic gliomas. Chin J Neurosurg 2006, 22, 636-639.
32. Jia, Z.F.; Pu, P.Y.; Kang, C.S.; et al. Influence of SEPT7 on biological characters of glioma cell line TJ905. Zhonghua Wai Ke Za Zhi 2007, 45, 1420-1423.
33. Wang, S.L.; Li, F.; Pu, P.Y.; et al. The establishment and characteristics of human glioblastoma cell lines TJ899 and TJ905. J Tianjin Med 1996, 12, 416-418.
34. Mohan, P.M.; Chintala, S.K.; Mohanam, S.; et al. Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth. Cancer Res 1999, 59, 3369-3373.
35. Jia, Z.F.; Pu, P.Y.; Kang, C.S.; et al. Effect of SEPT7 on the malignant phenotype of transplanted glioma in nude mice. Chin J Oncol 2008, 30, 3-7.
36. Liotta, L.A. Tumor invasion and metastasis role of the extracellular matrix: Rhoads memorial award lecture. Cancer Res 1986, 46, 1-7.
37. Bello, L.; Francolini, M.; Marthyn, P.; et al. Alpha(v) beta 3 and alpha(v) beta 5 integrin expression in glioma periphery. Neuro-surgery 2001, 49, 380-389.
38. Bello, L.; Lucini, V.; Giussani, C.; et al. IS20I, a specific alphavbeta3 integrin inhibitor, reduces glioma growth in vivo. Neurosurgery 2003, 52, 177-185.
39. Guo, P.; Imanishi, Y.; Cackowski, F.C.; et al. Upregulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma. Am J Pathol 2005, 166, 877-890.
40. Nakado, M.; Kita, D.; Futamik, K.; et al. Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinase 2 in invasion and dissemination of human malignant glioma. J Neurosurg 2001, 94, 464-473.
41. Lakka, S.S.; Rajan, M.; Gondi, C.; et al. Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion. Oncogene 2002, 21, 8011-8819.
42. Nuttall, R.K.; Pennington, C.J.; Taplin, J.; et al. Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells. Mol Cancer Res 2003, 1, 333-345.
43. Gomez, D.E.; Alonso, D.F.; Yoshiji, H.; Thorgeirsson, U.P. Tissue inhibitors of metalloproteinases: structure, regulation, and biological functions. Eur J Cell Biol 1997, 74, 111-122.
44. Yin, Z.Q., Hou, R.G.; Wang, T.; et al. The expression and significance of MMP-2 and TIMP-2 in gliomas. Chin J Neuromed 2005, 4, 1097-1100.
45. Lampert, K.; Machein, M.R.; Conca, W.; et al. Expression of matrix metalloproteinases and the tissue inhibitors in human brain tumors. Am J Pathol 1998, 153, 429-437.
46. Nakano, A.; Tani, E.; Yamamoto, Y.; et al. Increased expression of gelatinases A and B, matrilysin and TIMP1 genes in human malignant gliomas. Nippon Rinsho 1995, 53, 1816-1821.
47. Gerharz, C., Mou, R.; Meister, P.; et al. Cytoskeletal heterogeneity of an epithelioid sarcoma with expression of vimentin, cytokeratin, and neurofilaments. Am J Surg Pathol 1990, 14, 274-282.
48. Sabine, H.; Patricia, C.; Laila, S.; et al. IL-2-dependent expression of genes involved in cytoskeleton organization, oncogene regulation, and transcriptional control. J Immunol 1999, 162, 3280-3288.