Comparison of semiquantitative test strips, urine protein electrophoresis, and an immunoturbidimetric assay for measuring microalbuminuria in dogs

Veterinary Clinical Pathology

Volumn 38, Issue 4, 2009, Pages 485-492

  Murgier, Philippe ^a   Jakins, Amanda ^a   Bexfield, Nicholas ^a   Archer, Joy ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Dog; kidney disease; Method comparison; Microalbuminuria; Urine

Indexed keywords

ALBUMINURIA; ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMISTRY; DOG; DOG DISEASE; ELECTROPHORESIS; IMMUNOASSAY; METHODOLOGY; PHOTOMETRY; REPRODUCIBILITY; TEST STRIP; URINALYSIS; URINE;

ALBUMINURIA; ANIMALS; DOG DISEASES; DOGS; ELECTROPHORESIS; IMMUNOASSAY; NEPHELOMETRY AND TURBIDIMETRY; REAGENT STRIPS; REPRODUCIBILITY OF RESULTS; URINALYSIS; URINE;

CANIS FAMILIARIS;

EID: 77149132453     PISSN: 02756382     EISSN: 1939165X     Source Type: Journal    
DOI: 10.1111/j.1939-165X.2009.00176.x     Document Type: Article

References (20)

1. Russo LM, Bakris GL, Comper WD. Renal handling of albumin: a critical review of basic concepts and perspective. Am J Kidney Dis. 2002;39:899-919.
2. Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med. 1998;339:1448-1456.
3. th ed. St Louis, MO: Moby Elsevier; 2007:613-691.
4. Pressler BM, Vaden SL, Jensen WA, Simpson D. Detection of canine microalbuminuria using semiquantitative test strips designed for use with human urine. Vet Clin Pathol. 2002;31:56-60.
5. Grauer GF. Measurement, interpretation, and implications of proteinuria and albuminuria. Vet Clin North Am Small Anim Pract. 2007;37:283-295.
6. Struble LA, Feldman EC, Nelson RW, Kass PH. Systemic hypertension and proteinuria in dogs with diabetes mellitus. J Am Vet Med Assoc. 1998;213:822-825.
7. Gentilini F, Dondi F, Mastrorilli C, et al. Validation of a human immunoturbidimetric assay to measure canine albumin in urine and cerebrospinal fluid. J Vet Diagn Invest. 2005;17:179-183.
8. Lees GE. Early diagnosis of renal disease and renal failure. Vet Clin North Am Small Anim Pract. 2004; 34:867-885.
9. Whittemore JC, Gill VL, Jensen WA, Radecki SV, Lappin MR. Evaluation of the association between microalbuminuria and the urine albumin-creatinine ratio and systemic disease in dogs. J Am Vet Med Assoc. 2006;229:958-963.
10. Nabity NB, Boggess MM, Kashtan CE, Lees GE. Day-today variation of the urine protein:creatinine ratio in female dogs with stable glomerular proteinuria caused by x-linked hereditary nephropathy. J Vet Intern Med. 2007;21:425-430.
11. Brinkman JW, de Zeeuw D, Duker JJ, et al. Falsely low urinary albumin concentrations after prolonged frozen storage of urine samples. Clin Chem. 2005;51: 2181-2183.
12. Brinkman JW, de Zeeuw D, Heerspink HJL, et al. Apparent loss of urinary albumin during long term frozen storage: HPLC vs Immunonephelometry. Clin Chem. 2007;53:1520-1526.
13. Jensen AL, Kjelgaard-Hansen M. Method comparison in the clinical laboratory. Vet Clin Pathol. 2006; 35:276-286.
14. th ed. New York, NY: Saunders Elsevier; 2008:201-228.
15. Altman DG. Practical Statistics for Medical Research. Florida: Chapman & Hall/CRC Press; 1999.
16. Gray AT, Cohn LA, Kerl ME, Jensen WA. The effect of exercise on urinary albumin excretion in dogs. JVet Intern Med. 2004;18:52-55.
17. Vaden SL, Pressler BM, Lappin MR, Jensen WA. Effects of urinary tract inflammation and sample blood contamination on urine albumin and total protein concentrations in canine urine samples. Vet Clin Pathol. 2004;33:14-19.
18. Tencer J, Thysell H, Andersson K, Grbb A. Longterm stability of albumin, protein HC, immunoglobin G k, and λ chain-immunoreactivity, orosomucoid and ά-1 antitrypsin in urine stored at - 20°C. Scan J Urol Nephrol. 1997;31:67-71.
19. Garner BC, Wiedmeyer CE. Comparison of a semiquantitative point of care assay for the detection of canine microalbuminuria with routine semiquantitative methods for proteinuria. Vet Clin Pathol. 2007;36:240-244.
20. Miller WG, Burns DE, Hortin GL. Current issues in measurement and reporting of urinary albumin excretion. Clin Chem. 2009;55:24-38.