Preparation and characteristics of interferon-alpha poly(lactic-co-glycolic acid) microspheres

Journal of Microencapsulation

Volumn 27, Issue 2, 2010, Pages 133-141

  Yang, Fan ^a   Song, Feng Lan ^a   Pan, Yu Fang ^a   Wang, Zhao Yang ^b   Yang, Yi Qun ^a   Zhao, Yao Ming ^c   Liang, Shi Zhong ^b   Zhang, Yong Ming ^c  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Concentration; Interferon ; Microspheres; Poly(lactide co glycolide); Preparation; Viscosity

Indexed keywords

ALPHA INTERFERON; MICROSPHERE; POLYGLACTIN; DELAYED RELEASE FORMULATION; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; BIODEGRADABILITY; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; DRUG DEGRADATION; DRUG SYNTHESIS; EVAPORATION; IN VITRO STUDY; MICROEMULSION; MICROENCAPSULATION; POROSITY; SURFACE PROPERTY; VISCOSITY; CELL LINE; CHEMISTRY; DELAYED RELEASE FORMULATION; HUMAN; METABOLISM;

CELL LINE; DELAYED-ACTION PREPARATIONS; HUMANS; INTERFERON-ALPHA; LACTIC ACID; POLYGLYCOLIC ACID; POROSITY; VISCOSITY;

EID: 77149131818     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652040903052010     Document Type: Article

References (36)

1. Alpaslan C, Irie K, Takahashi K, Ohashi N, Sakai H, Nakajima T, et al. 1996. Long-term evaluation of recombinant human bone morphogenetic protein-2 induced bone formation with a biologic and synthetic delivery system. Br J Oral Maxillofac Surg 34:414-418.
2. Aubert-Pouessel A, Venier-Julienne MC, Clavreul A, Sergent M, Jollivet C, Montero-Menei CN, et al. 2004. In vitro study of GDNF release from biodegradable PLGA microspheres. J Contr Rel 95:463-475
3. Beilharz MW. 2000. Therapeutic potential for orally administered type 1 interferons. Pharm Sci Tech Today 3:193-197.
4. Carino GP, Jacob JS, Mathiowitz E. 2000. Nanosphere based oral insulin delivery. J Contr Rel 65:261-269.
5. Carrasquillo KG, Stanley AM, Aponte-Carro JC, De Jesus P, Costantino HR, Bosques CJ, et al. 2001. Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein. J Contr Rel 76:199-208.
6. Chen L, Apte RN, Cohen S. 1997. Characterization of PLGA microspheres for the controlled delivery of IL-1a for tumor immunotherapy. J Contr Rel 43:261-272.
7. Diwan M, Park TG. 2003. Stabilization of recombinant interferon-alpha by pegylation for encapsulation in PLGA microspheres. Int J Pharm 252:111-122.
8. Dogar V, Sokhey J, Kumar S, Sood DK, Tahlan AK. 2002. Interference of thiomersal in biologicals during protein estimation. Biologicals 30:271-275.
9. Feng L, Qi XR, Zhou XJ, Maitani Y, Wang SC, Jiang Y, et al. 2006. Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres. J Contr Rel 112:35-42.
10. Filipovic-Grcic J, Crc V, Jalsenjak I. 1999. Albumin-loaded PLA and PLGA microspheres: In vitro evaluation. Boll Chim Farm 138:14-18.
11. Grizzi I, Garreau H, Li S, Vert M. 1995. Hydrolytic degradation of devices based on poly(DL-lactic acid) size-dependence. Biomaterials 16:305-311.
12. Hora MS, Rana RK, Nunberg JH, Tice TR, Gilley RM, Hudson ME. 1990. Controlled release of interleukin-2 from biodegradable microspheres. Biotechnology (NY) 8:755-758.
13. Kim HK, Park TG. 2004. Comparative study on sustained release of human growth hormone from semi-crystalline poly(L-lactic acid) and amorphous poly(D,L-lactic-co-glycolic acid) microspheres: Morphological effect on protein release. J Contr Rel 98:115-125.
14. Kim TH, Lee H, Park TG. 2002. Pegylated recombinant human epidermal growth factor (rhEGF) for sustained release from biodegradable PLGA microspheres. Biomaterials 23:2311-2317.
15. Kozlowski A, Harris JM. 2001. Improvements in protein PEGylation: Pegylated interferons for treatment of hepatitis C. J Contr Rel 72:217-224. (Pubitemid 32522359)
16. Lam XM, Duenas ET, Cleland JL. 2001. Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres. J Pharm Sci 90:1356-1365.
17. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
18. Nam YS, Song SH, Choi JY, Park TG. 2000. Lysozyme microencapsulation within biodegradable PLGA microspheres: Urea effect on protein release and stability. Biotechnol Bioeng 70:270-277.
19. Ogawa Y, Yamamoto M, Okada H, Yashiki T, Shimamoto T. 1988. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chem Pharm Bull (Tokyo) 36:1095-1103.
20. Ogawa Y, Yamamoto M, Takada S, Okada H, Shimamoto T. 1988. Controlled-release of leuprolide acetate from polylactic acid or copoly (lactic/glycolic) acid microcapsules: Influence of molecular weight and copolymer ratio of polymer. Chem Pharm Bull (Tokyo) 36:1502-1507.
21. Pistel KF, Kissel T. 2000. Effects of salt addition on the microencapsulation of proteins using W/O/W double emulsion technique. J Microencapsulation 17:467-483.
22. Reich G. 1998. Ultrasound-induced degradation of PLA and PLGA during microsphere processing: Influence of formulation variables. Eur J Pharm Biopharm 45:165-171.
23. Sanchez A, Tobio M, Gonzalez L, Fabra A, Alonso MJ. 2003. Biodegradable micro- and nanoparticles as long-term delivery vehicles for interferonalpha. Eur J Pharm Sci 18:221-229.
24. Spenlehauer G, Vert M, Benoit JP, Boddaert A. 1989. In vitro and in vivo degradation of poly(D,L lactide/glycolide) type microspheres made by solvent evaporation method. Biomaterials 10:557-563.
25. Sun Y, Wang J, Zhang X, Zhang Z, Zheng Y, Chen D, et al. 2008. Synchronic release of two hormonal contraceptives for about one month from the PLGA microspheres: In vitro and in vivo studies. J Contr Rel 129:192-199.
26. Uchida T, Goto S. 1994. Oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin as vaccine formulation: Particle size study. Biol Pharm Bull 17:1272-1276.
27. Ungaro F, De Rosa G, Miro A, Quaglia F, La Rotonda MI. 2006. Cyclodextrins in the production of large porous particles: Development of dry powders for the sustained release of insulin to the lungs. Eur J Pharm Sci 28:423-432.
28. Vert M, Mauduit J, Li S. 1994. Biodegradation of PLA/GA polymers: Increasing complexity. Biomaterials 15:1209-1213.
29. Visscher GE, Pearson JE, Fong JW, Argentieri GJ, Robison RL, Maulding HV. 1988. Effect of particle size on the in vitro and in vivo degradation rates of poly(DL-lactide-co-glycolide) microcapsules. J Biomed Mater Res 22:733-746.
30. Waeckerle-Men Y, Allmen EU, Gander B, Scandella E, Schlosser E, Schmidtke G, et al. 2006. Encapsulation of proteins and peptides into biodegradable poly(D,L-lactide-co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells. Vaccine 24:1847-1857.
31. Wang J, Chua KM, Wang CH. 2004. Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres. J Colloid Interface Sci 271:92-101.
32. Wang YS, Youngster S, Grace M, Bausch J, Bordens R, Wyss DF. 2002. Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications. Adv Drug Deliv Rev 54:547-570.
33. Wei G, Pettway GJ, McCauley LK, Ma PX. 2004. The release profiles and bioactivity of parathyroid hormone from poly(lactic-co-glycolic acid) microspheres. Biomaterials 25:345-352.
34. Yamaguchi Y, Takenaga M, Kitagawa A, Ogawa Y, Mizushima Y, Igarashi R. 2002. Insulin-loaded biodegradable PLGA microcapsules: Initial burst release controlled by hydrophilic additives. J Contr Rel 81:235-249.
35. Zannou EA, Streng WH, Stella VJ. 2001. Osmotic properties of sulfobutylether and hydroxypropyl cyclodextrins. Pharm Res 18:1226-1231.
36. Zhou S, Deng X, He S, Li X, Jia W, Wei D, et al. 2002. Study on biodegradable microspheres containing recombinant interferon-alpha-2a. J Pharm Pharmacol 54:1287-1292.