Computer-aided non-contrast CT-based quantification of pericardial and thoracic fat and their associations with coronary calcium and metabolic syndrome

Atherosclerosis

Volumn 209, Issue 1, 2010, Pages 136-141

  Dey, Damini ^a,b   Wong, Nathan D ^c   Tamarappoo, Balaji ^a   Nakazato, Ryo ^a   Gransar, Heidi ^a   Cheng, Victor Y ^a   Ramesh, Amit ^a   Kakadiaris, Ioannis ^d   Germano, Guido ^a,b   Slomka, Piotr J ^a,b   Berman, Daniel S ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d University of Houston   (United States)

Author keywords

Coronary calcium; Metabolic syndrome; Non contrast CT; Pericardial fat; Thoracic fat

Indexed keywords

ADIPONECTIN; CALCIUM; GLUCOSE; HIGH DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ABDOMINAL FAT; ADIPOSE TISSUE; ADULT; ARTICLE; AUTOMATION; BODY MASS; CALCIUM SIGNALING; CARDIOVASCULAR RISK; COMPUTER AIDED DESIGN; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY RISK; DISEASE ASSOCIATION; FEMALE; HUMAN; IMAGE ANALYSIS; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; OBSERVER VARIATION; PERICARDIUM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; RETROSPECTIVE STUDY; RISK ASSESSMENT; THORAX; WAIST CIRCUMFERENCE;

ADIPOSE TISSUE; BODY MASS INDEX; CALCIUM; CORONARY VESSELS; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PERICARDIUM; RADIOGRAPHY, THORACIC; TOMOGRAPHY, X-RAY COMPUTED; WAIST CIRCUMFERENCE;

EID: 77049125938     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.08.032     Document Type: Article

References (24)

1. Iacobellis G., Pistilli D., Gucciardo M., et al. Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease. Cytokine 29 6 (21 2005) 251-255
2. Kortelainen M.L. Myocardial infarction and coronary pathology in severely obese people examined at autopsy. Int J Obes Relat Metab Disord 26 1 (2002) 73-79
3. Rosito G.A., Massaro J.M., Hoffmann U., et al. Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: The Framingham Heart Study. Circulation 117 5 (5, 2008) 605-613
4. Gorter P.M., van Lindert A.S.R., de Vos A.M., et al. Quantification of epicardial and peri-coronary fat using cardiac computed tomography; reproducibility and relation with obesity and metabolic syndrome in patients suspected of coronary artery disease. Atherosclerosis 197 2 (2008) 896-903
5. Ding J., Kritchevsky S.B., Harris T.B., et al. The association of pericardial fat with calcified coronary plaque. Obesity 16 8 (2008) 1914-1919
6. Wheeler G.L., Shi R., Beck S.R., et al. Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in type 2 diabetic families. Invest Radiol 40 2 (2005) 97-101
7. Dey D., Suzuki Y., Suzuki S., et al. Automated quantitation of pericardiac fat from non-contrast CT. Invest Radiol 43 2 (2008) 145-153
8. Taguchi R., Takasu J., Itani Y., et al. Pericardial fat accumulation in men as a risk factor for coronary artery disease. Atherosclerosis 157 1 (2001) 203-209
9. Mahabadi A.A., Massaro J.M., Rosito G.A., et al. Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. Eur Heart J 30 7 (2009) 850-856
10. Daniell AL F.J., Ben-Yosef N., Wong N.D., et al. Concordance of coronary calcium estimation between multi-detector and electron beam CT. Circulation 106 II (2002) 479
11. Agatston A.S., Janowitz W.R., Hildner F.J., et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am College Cardiol 15 4 (1990) 827-832
12. Yoshizumi T., Nakamura T., Yamane M., et al. Abdominal fat: standardized technique for measurement at CT. Radiology 211 1 (1999) 283-286
13. Kvist H., Chowdhury B., Grangard U., Tylen U., and Sjostrom L. Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations. Am J Clin Nutr 48 6 (1988) 1351-1361
14. Catmull E, Rom R. A class of local interpolating splines. Vol 74: Proceedings of International Conference on Computer Aided Geometric Design; 1974:317-326.
15. Sjostrom L., Kvist H., Cederblad A., and Tylen U. Determination of total adipose tissue and body fat in women by computed tomography, 40K, and tritium. Am J Physiol 250 6 Pt 1 (1986) E736-745
16. Wajchenberg B. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 21 6 (2000) 697-738
17. Grundy S.M., Cleeman J.I., Daniels S.R., et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112 17 (25 2005) 2735-2752
18. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). Jama. May 16 2001; 285(19):2486-2497.
19. Wong N.D., Sciammarella M.G., Polk D., Gallagher A., et al. The metabolic syndrome, diabetes, and subclinicalatherosclerosis assessed by coronary calcium. J Am College Cardiol 41 9 (2003) 1547-1553
20. Janssen I., Katzmarzyk P.T., and Ross R. Body mass index, waist circumference, and health risk: evidence in support of current National Institutes of Health guidelines. Arch Intern Med 162 18 (14 2002) 2074-2079
21. Greif M., Becker A., von Ziegler F., et al. Pericardial adipose tissue determined by dual source CT is a risk factor for coronary atherosclerosis. Arterioscler Thromb Vasc Biol 29 5 (2009) 781-786
22. Mazurek T., Zhang L., Zalewski A., et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 108 20 (18 2003) 2460-2466
23. Bandekar A., Naghavi M., and Kakadiaris I.A. Automated Pericardial Fat Quantification in CT Data. Proc. of the 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, (EMBS'06). New York, August 30-September 3 (2006)
24. Cheng V, Dey, D, Tamarappoo B, et al. Pericardial and thoracic fat burden in asymptomatic patients who experience adverse cardiovascular events after non-contrast CT for calcium scoring. Accepted abstract, American Heart Association Annual Meeting; Circulation Supplement 2009: in press (abstract).