Ultrasonic Microbubble-Mediated Gene Delivery Causes Phenotypic Changes of Human Aortic Endothelial Cells

Ultrasound in Medicine and Biology

Volumn 36, Issue 3, 2010, Pages 449-458

  Su, Cheng Huang ^a,b   Chang, Chiung Yin ^a   Wang, Hsueh Hsiao ^a   Wu, Yih Jer ^a   Bettinger, Thierry ^c   Tsai, Cheng Ho ^a   Yeh, Hung I ^a  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b MACKAY MEDICAL COLLEGE   (Taiwan)

^c Bracco Suisse SA   (Switzerland)

Author keywords

Endothelial cells; Gene expression; Migration; Phenotypic changes; Proliferation; Ultrasonic microbubble transfection

Indexed keywords

ADHESION MOLECULES; ADVERSE EFFECT; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXPRESSION PROFILE; GENE DELIVERY; HUMAN AORTIC ENDOTHELIAL CELLS; IN-VITRO; IN-VIVO; INTERCELLULAR ADHESION MOLECULE-1; MICRO-BUBBLE; MICROBUBBLES; MIGRATION; MRNA LEVEL; NONVIRAL; P-SELECTIN; PHENOTYPIC CHANGES; PROLIFERATION; PROTEIN LEVEL; REAL TIME RT-PCR; REPORTER GENE; TRANSFECTED CELLS; TYROSINE KINASE; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR ENDOTHELIAL CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR; VON WILLEBRAND FACTOR; WESTERN BLOTTING;

ACOUSTIC WAVES; ADHESION; AMINO ACIDS; BIOACTIVITY; BLOOD VESSEL PROSTHESES; BLOOD VESSELS; CELL ADHESION; GENE EXPRESSION; GENE TRANSFER; MOLECULES; NITRIC OXIDE; NUCLEIC ACIDS; PHOSPHATASES; PLANTS (BOTANY); PROTEINS; SELF ASSEMBLY; ULTRASONICS;

ENDOTHELIAL CELLS;

CONNEXIN 43; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; LUCIFERASE; MESSENGER RNA; PADGEM PROTEIN; PLASMID DNA; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR;

AORTA; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MICROBUBBLE; NONVIRAL GENE DELIVERY SYSTEM; PHENOTYPE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; ULTRASOUND; UPREGULATION; WESTERN BLOTTING;

AORTA; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; LUCIFERASES; MICROBUBBLES; PHENOTYPE; PLASMIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; ULTRASONICS;

EID: 77049106535     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2009.11.006     Document Type: Article

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