Validation, reproducibility and safety of trans dermal electrical stimulation in chronic pain patients and healthy volunteers

BMC Neurology

Volumn 10, Issue 1, 2010, Pages

  Lecybyl, Remigiusz ^a,b,c,d   Acosta, Juan ^a   Ghoshdastidar, Joydeep ^a   Stringfellow, Kinga ^a   Hanna, Magdi ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c Anesthesiology Department   (United Kingdom)

^d UNIVERSITY HOSPITAL LEWISHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLODYNIA; ARTICLE; CHRONIC PAIN; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; HUMAN; HYPERALGESIA; LOW BACK PAIN; MALE; NEUROPATHIC PAIN; PATIENT SAFETY; RADICULAR PAIN; RADICULOPATHY; RATING SCALE; REPRODUCIBILITY; TRANSCUTANEOUS NERVE STIMULATION; VALIDATION PROCESS; VISUAL ANALOG SCALE; AREA UNDER THE CURVE; CHRONIC DISEASE; HABITUATION; METHODOLOGY; MIDDLE AGED; PAIN; PAIN ASSESSMENT; PATHOPHYSIOLOGY; STATISTICAL MODEL; STIMULATION; TIME;

ADULT; AGED; AREA UNDER CURVE; CHRONIC DISEASE; HABITUATION, PSYCHOPHYSIOLOGIC; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; PAIN; PAIN MEASUREMENT; PHYSICAL STIMULATION; REPRODUCIBILITY OF RESULTS; TIME FACTORS; TRANSCUTANEOUS ELECTRIC NERVE STIMULATION; YOUNG ADULT;

EID: 76949107799     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/1471-2377-10-5     Document Type: Article

References (25)

1. Vierck CJ, Hansson PT, Yezierski RP. Clinical and pre-clinical pain assessment: are we measuring the same thing?. Pain 2008, 135(1-2):7-10. 10.1016/j.pain.2007.12.008, 18215466.
2. Goldstein DJ, Wang O, Todd LE, Gitter BD, DeBrota DJ, Iyengar S. Study of the analgesic effect of lanepitant in patients with osteoarthritis pain. Clinical pharmacology and therapeutics 2000, 67(4):419-426. 10.1067/mcp.2000.105243, 10801252.
3. Hill R. NK1 (substance P) receptor antagonists--why are they not analgesic in humans?. Trends in pharmacological sciences 2000, 21(7):244-246. 10.1016/S0165-6147(00)01502-9, 10871891.
4. Arendt-Nielsen L, Curatolo M, Drewes A. Human experimental pain models in drug development: translational pain research. Curr Opin Investig Drugs 2007, 8(1):41-53.
5. Bromm B, Meier W, Scharein E. Imipramine reduces experimental pain. Pain 1986, 25:245-57. 10.1016/0304-3959(86)90100-4, 3523396.
6. Hardy JD, Wolff HG, Goodel H. Experimental evidence on the nature of cutaneous hyperalgesia. J Clin Invest 1950, 29:115-140. 10.1172/JCI102227, 439732, 15399521.
7. Inui K, Tran TD, Hoshiyama M, Kakigi R. Preferential stimulation of Adelta fibers by intra-epidermal needle electrode in humans. Pain 2002, 96:247-52. 10.1016/S0304-3959(01)00453-5, 11972996.
8. Koppert W, Dern SK, Sittl R, Albrecht S, Schüttler J, Schmelz M. A new model of electrically evoked pain and hyperalgesia in human skin: the effects of intravenous alfentanil, S(+)-ketamine, and lidocaine. Anesthesiology 2001, 95(2):395-402. 10.1097/00000542-200108000-00022, 11506112.
9. Lewis T. Experiments relating to cutaneous hyperalgesia and its spread through somatic nerves. Clin Sci 1936, 2:373-421.
10. Filitz J, Ihmsen H, Günther W, Tröster A, Schwilden H, Schüttler J, Koppert W. Supra-additive effects of tramadol and acetaminophen in a human pain model. Pain 2008, 136(3):262-70. 10.1016/j.pain.2007.06.036, 17709207.
11. Chizh BA, Göhring M, Tröster A, Quartey GK, Schmelz M, Koppert W. Effects of oral pregabalin and aprepitant on pain and central sensitization in the electrical hyperalgesia model in human volunteers. Br J Anaesth 2007, 98(2):246-54. 10.1093/bja/ael344, 17251214.
12. Chizh BA, Dusch M, Puthawala M, Schmelz M, Cookson LM, Martina R, Brown J, Koppert W. The effect of intravenous infusion of adenosine on electrically evoked hyperalgesia in a healthy volunteer model of central sensitization. Anesth Analg 2004, 99(3):816-22. 10.1213/01.ANE.0000132995.35119.99, 15333416.
13. Koppert W, Filitz J, Troster A, Ihmsen H, Angst M, Flor H, Schuttler J, Schmelz M. Activation of naloxone-sensitive and -insensitive inhibitory systems in a human pain model. J Pain 2005, 6(11):757-764. 10.1016/j.jpain.2005.07.002, 16275600.
14. Koppert W, Angst M, Alsheimer M, Sittl R, Albrecht S, Schüttler J, Schmelz M. Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans. Pain 2003, 106(1-2):91-9. 10.1016/S0304-3959(03)00294-X, 14581115.
15. Koppert W, Ihmsen H, Körber N, Wehrfritz A, Sittl R, Schmelz M, Schüttler J. Different profiles of buprenorphine-induced analgesia and antihyperalgesia in a human pain model. Pain 2005, 118(1-2):15-22. 10.1016/j.pain.2005.06.030, 16154698.
16. Singler B, Tröster A, Manering N, Schüttler J, Koppert W. Modulation of remifentanil-induced postinfusion hyperalgesia by propofol. Anesth Analg 2007, 104(6):1397-403. 10.1213/01.ane.0000261305.22324.f3, 17513631.
17. Tröster A, Sittl R, Singler B, Schmelz M, Schüttler J, Koppert W. Modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by parecoxib in humans. Anesthesiology 2006, 105(5):1016-23. 10.1097/00000542-200611000-00024, 17065897.
18. Bouhassira D, Attal N, Alchaar H, Boureau F, Brochet B, Bruxelle J, Cunin G, Fermanian J, Ginies P, Grun-Overdyking A, Jafari-Schluep H, Lanteri-Minet M, Laurent B, Mick G, Serrie A, Valade D, Vicaut E. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain 2005, 114(1-2):29-36. 10.1016/j.pain.2004.12.010, 15733628.
19. Bouhassira D, Lanteri-Minet M, Attal N, Laurent B, Touboul C. Prevalence of chronic pain with neuropathic characteristics in the general population. Pain 2008, 136(3):380-7. 10.1016/j.pain.2007.08.013, 17888574.
20. Lecybyl R, Acosta-Guillen J, Hanna M. Development of a new electrical model of neuropathic pain which mimics electrical discharge. J Pain 2006, 7(2 s2).
21. Rolke R, Magerl W, Campbell KA, Schalber C, Caspari S, Birklein F, Treede RD. Quantitative sensory testing: a comprehensive protocol for clinical trials. European journal of pain (London, England) 2006, 10(1):77-88. 10.1016/j.ejpain.2005.02.003, 16291301.
22. Rolan P. The contribution of clinical pharmacology surrogates and models to drug development- a critical appraisal. Br J Clin Pharmacol 1997, 44:219-225. 10.1046/j.1365-2125.1997.t01-1-00583.x, 2042843, 9296315.
23. Woolf CJ, Mannion RJ. Neuropathic pain: aetiology, symptom, mechanism and management. The lancet 1999, (353):1995-64.
24. Treede RD, Handwerker HO, Baumgartner U, Meyer RA, Magerl W. Hyperalgesia and Allodynia: Taxonomy, assessment and mechanisms; Hyperalgesia and Allodynia: molecular mechanisms and clinical implications. Prog Pain Res Menage 2004, 30:3-15.
25. Klein T, Magerl W, Hopf HC, Sandkuhler J, Treede RD. Perceptual correlates of nociceptive long-term potentiation and long-term depression in humans. J Neurosci 2004, 24(4):964-971. 10.1523/JNEUROSCI.1222-03.2004, 14749441.