Preparation, characterization, and drug-release properties of pH/temperature-responsive poly(N-isopropylacrylamide)/chitosan semi-IPN hydrogel particles

Journal of Applied Polymer Science

Volumn 116, Issue 3, 2010, Pages 1342-1347

  Chen, Xiaochun ^a   Song, He ^a   Fang, Ting ^a   Bai, Jianxin ^a   Xiong, Jian ^a   Ying, Hanjie ^a  

^a NANJING TECH UNIVERSITY   (China)

Author keywords

Drug release systems; Hydrogels; Semi interpenetrating networks (semi IPN); Stimuli sensitive polymers

Indexed keywords

CYCLIC ADENOSINE; DRUG RELEASE; DRUG RELEASE SYSTEM; DRUG RELEASE SYSTEMS; INVERSE SUSPENSION POLYMERIZATION; LOWER CRITICAL SOLUTION TEMPERATURE; MODEL DRUGS; MONOPHOSPHATES; N-ISOPROPYLACRYLAMIDES; PH VALUE; RELEASE BEHAVIORS; RELEASE PROPERTY; SEMI-INTERPENETRATING NETWORKS (SEMI-IPN); SEMI-INTERPENETRATING POLYMER NETWORK HYDROGEL; SEMI-IPN HYDROGELS; STIMULI-SENSITIVE POLYMERS; SWELLING RATIO; TEMPERATURE-SENSITIVE;

ACRYLIC MONOMERS; AMIDES; CHITIN; CHITOSAN; FETAL MONITORING; INTERPENETRATING POLYMER NETWORKS; SUSPENSIONS (FLUIDS); SWELLING;

HYDROGELS;

CHITOSAN; CONTROLLED RELEASE; DRUG DELIVERY; HYDROGEL; PARTICLE SIZE; PH; POLYMERIZATION; SWELLING;

EID: 76949107366     PISSN: 00218995     EISSN: 10974628     Source Type: Journal    
DOI: 10.1002/app.31583     Document Type: Article

References (24)

1. Qiu, Y.; Park, K. Adv Drug Delivery Rev 2001, 539, 321.
2. Kaetsu, I.; Uchida, K.; Sutani, K.; Sakata, S. Radiat Phys Chem 2000, 57, 465.
3. Chen, J.; Sun, J.; Yang, L. M.; Zhang, Q. F.; Zhu, H.; Wu, H. F. Radiat Phys Chem 2007, 76, 1425.
4. Langer, R.; Peppas, N. A. AIChE J 2003, 49, 2990.
5. Pelton, R. H. Adv Colloid Interface Sci 2000, 85, 1.
6. Shimizu, T.; Yamato, M.; Kikuchi, A.; Okano, T. Tissue Eng 2001, 7, 141.
7. Yu, S. Y.; Hu, J. H.; Pan, X. Y.; Yao, P.; Jiang, M. Langmuir 2006, 22, 2754.
8. Matsusaki, M.; Akashi, M. Biomacromolecules 2005, 6, 3351.
9. Lo, C. L.; Lin, K. M.; Hsiue, G. H. J. J Controlled Release 2005, 104, 477.
10. Shi, J.; Alves, N. M.; Mano, J. F. Macromol Biosci 2006, 6, 358.
11. Hoffman, A. S. J Controlled Release 1987, 6, 297.
12. Sun, G.; Zhang, X. Z.; Chu, C. C. J Mater Sci: Mater Med 2007, 18, 1563.
13. Kim, S. Y.; Cho, S. M.; Lee, Y. M.; Kim, S. J. J Appl Polym Sci 2000, 78, 1381.
14. Cheng, M. Y.; Deng, J. U.; Yang, F.; Gong, Y. D.; Zhao, N. M.; Zhang, X. F. Biomaterials 2003, 24, 2871.
15. Peniche, C.; Monal, W. A.; Peniche, H.; Acosta, N. Macromol Biosci 2003, 3, 511.
16. Berger, J.; Reist, M. J.; Mayer, M.; Felt, O.; Gurny, R. Eur J Pharm Sci 2004, 57, 35.
17. Lee, W. F.; Chen, Y. J. J Appl Polym Sci 2001, 82, 2487.
18. Verestiuc, L.; Ivanov, C.; Barbu, E.; Tsibouklis, J. Int J Pharm 2004, 269, 185.
19. Carmen, A. L.; Angel, C.; Alexander, S. D.; Natalia, V. G.; Tatiana, V. B.; Valerij, Y. G. J Controlled Release 2005, 102, 629.
20. Zhang, J.; Peppas, N. A. Macromolecules 2000, 33, 102.
21. Vachoud, L.; Zydowicz, N.; Domard, A. Carbohydr Res 2000, 326, 295.
22. Berth, G.; Dautzenberg, H. Carbohydr Polym 2002, 47, 39.
23. Wu, J. Y.; Liu, S. Q.; Heng, W. S.; Yang, Y. Y. J Controlled Release 2005, 102, 361.
24. Matsudo, T.; Ogawa, E.; Kokufuta, E. Biomacromolecules 2003, 4, 728.