Flow-based measurements of von Willebrand factor (VWF) function: Binding to collagen and platelet adhesion under physiological shear rate

Thrombosis Research

Volumn 125, Issue 3, 2010, Pages 239-245

  Fuchs, Birte ^a   Budde, Ulrich ^b   Schulz, Andrea ^c   Kessler, Craig M ^d   Fisseau, Claudine ^a   Kannicht, Christoph ^a  

^a Octapharma Research and Development   (Germany)

^b Aesculabor Hamburg GmbH   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d GEORGETOWN UNIVERSITY   (United States)

Author keywords

collagen; Flow chamber; platelet adhesion; VWF; VWF multimers

Indexed keywords

COLLAGEN; VON WILLEBRAND FACTOR;

ARTICLE; ATOMIC FORCE MICROSCOPY; PRIORITY JOURNAL; SHEAR RATE; THROMBOCYTE ADHESION;

BLOOD PLATELETS; COLLAGEN; HUMANS; PLATELET ADHESIVENESS; STRESS, MECHANICAL; VON WILLEBRAND FACTOR;

EID: 76949093734     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.08.020     Document Type: Article

References (37)

1. Ruggeri Z.M. Platelet and von Willebrand factor interactions at the vessel wall. Hamostaseologie 24 (2004) 1-11
2. Savage B., Saldivar E., and Ruggeri Z.M. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 84 (1996) 289-297
3. Matsushita T., Dong Z., and Sadler J.E. Von Willebrand's factor and von Willebrand's disease. Curr Opin Hematol 1 (1994) 362-368
4. Sadler J.E. Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem 67 (1998) 359-424
5. Dong J.-F. Cleavage of ultra-large von Willebrand factor by ADMATS-13 under flow conditions. J Thromb Haemost 3 (2005) 1710-1716
6. Slayter H., Loscalzo J., Bockenstedt P., and Handin R.I. Native conformation of human von Willebrand protein. Analysis by electron microscopy and quasi-elastic light scattering. J Biol Chem 260 (1985) 8559-8563
7. Kang I., Raghavachari M., Hofmann C.M., and Marchant R.E. Surface-dependent expression in the platelet GPIb binding domain within human von Willebrand factor studied by atomic force microscopy. Thromb Res 6 (2007) 731-740
8. Siedlecki C.A., Lestini B.J., Kottke-Marchant K.K., Eppell S.J., Wilson D.L., and Marchant R.E. Shear dependent changes in the three-dimensional structure of human von Willebrand factor. Blood 88 (1996) 2939-2950
9. Kehrel B. Platelet-collagen interactions. Semin Thromb Hemost 21 (1995) 123-129
10. Saelman E.U., Nieuwenhuis H.K., Hese K.M., de Groot P.G., Heijnen H.F., Sage E.H., et al. Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIα (α2β1-integrin). Blood 83 (1993) 1244-1250
11. Sixma J.J., van Zanten G.H., Saelman E.U.M., Verkleij M., Lankhof H., Nieuwenhuis H.K., et al. Platelet adhesion to collagen. Thromb Haemost 74 (1995) 454-459
12. Li F., Moake J.L., and McIntire L.V. Characterization of von Willebrand factor interaction with collagens in real time using surface plasmon resonance. Ann Biomed Eng 30 (2002) 1107-1116
13. Fischer B.E., Thomas K.B., and Dorner F. Von Willebrand factor: measuring its antigen or function? Correlation between the level of antigen, activity, and multimer size using various detection systems. Thromb Res 91 (1998) 39-43
14. Zwaginga J.J., Sakariassen K.S., King M.R., Diacovo T.G., Grabowski E.F., Nash G., et al. Can blood flow assays help to identify clinically relevant differences in von Willebrand factor functionality in von Willebrand disease types 1-3?. J Thromb Haemost 5 (2007) 2547-2549
15. Stadler M., Gruber G., Kannicht C., Biesert L., Radomski K.U., Suhartono H., et al. Characterisation of a novel high purity, double virus inactivated von Willebrand factor and factor VIII concentrate Wilate. Biologicals 34 (2006) 281-288
16. Tangelder G.J., Slaaf D.W., Arts T., and Reneman R.S. Wall shear rate in arterioles in vivo: least estimates from platelet velocity profiles. Am J Physiol 254 (1988) H1059-H1064
17. Stroev P.V., Hoskins P.R., and Easson W.J. Distribution of wall shear rate throughout the arterial tree: A case study. Atherosclerosis 191 (2007) 276-280
18. Budde U., Pieconka A., Will K., and Schneppenheim R. Laboratory testing for von Willebrand disease: contribution of multimer analysis to diagnosis and classification. Semin Thromb Hemost 32 (2006) 514-521
19. Vollmar B., Slotta J.E., Nickels R.M., Wenzel E., and Menger M.D. Comparative analysis of platelet isolation techniques for the in vivo study of the microcirculation. Microcirculation 10 (2003) 143-152
20. Vanhoorelbeke K., Depraetere H., Romijin R.A.P., Huizinga E.G., De Maeyer M., and Deckmyn H. A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction. J Biol Chem 278 (2003) 37815-37821
21. Moroi M., Jung S.M., Shinmyozu K., Tomiyama Y., Ordinas A., and Diaz-Ricart M. Analysis of platelet adhesion to a collagen-coated surface under flow conditions: the involvement of glycoprotein VI in the platelet adhesion. Blood 88 (1996) 2081-2092
22. Baumgartner H.R., and Haudenschild C. Adhesion of platelets to subendothelium. Ann NY Acad Sci 201 (1972) 22-36
23. Baumgartner H.R. The role of blood flow in platelet adhesion, fibrin deposition and formation of mural thrombi. Microvasc Res 5 (1973) 167-179
24. Sakariassen K.S., Aarts P.A.M.M., de Groot P.G., Houdijk W.P.M., and Sixma J.J. A perfusion chamber developed to investigate platelet interaction in flowing blood with human vessel wall cells, their extracellular matrix and purified components. J Lab Clin Med 102 (1983) 522-535
25. Bonnefoy A., Yamamoto H., Thys C., Kito M., Vermylen J., and Hoylaerts M.F. Shielding the front-strand beta 3 of the von Willebrand factor A1 domain inhibits its binding to platelet glycoprotein Ibalpha. Blood 10 (2003) 1375-1383
26. Zwaginga J.J., Sakariassen K.S., Nash G., King M.R., Heemskerk J.W.M., Frojmovic M., et al. Flow-based assays for global assessment of haemostasis. Part 2: Current methods and considerations for the future. J Thromb Haemost 4 (2006) 2716-2717
27. Chand S., McCraw A., Hutton R., Tuddenham E.G., and Goodall A.H. A two-site, monoclonal antibody-based immunoassay for von Willebrand factor-demonstration that VWF function resides in a conformational epitope. Thromb Haemost 55 (1986) 318-324
28. Murdock P.J., Woodhams B.J., Matthews K.B., Pasi K.J., and Goodall A.H. Von Willebrand factor activity detected in a monoclonal antibody-bases ELISA: an alternative to the ristocetin cofactor platelet agglutination assay for diagnostic use. Thromb Haemost 78 (1997) 1272-1277
29. Godall A.H., Jarvis J., Chand S., Rawlings E., O'Brien D.P., McGraw A., et al. An immunoradiometric assay for human factor VIII/von Willebrand factor (VIII:vWF) using a monoclonal antibody that defines a functional epitope. B J Haemat 59 (1985) 565-577
30. Wu Y.P., van Breugel H.H., Lankhof H., Wise R.J., Handin R.I., de Groot P.G., et al. Platelet adhesion to multimeric and dimeric von Willebrand factor and to collagen type III preincubated with von Willebrand factor. Arterioscler Thromb Vasc Biol 16 (1996) 611-620
31. Savage B., Sixma J.J., and Ruggeri Z.M. Functional self-association of von Willebrand factor during platelet adhesion under flow. Proc Natl Acad Sci U S A 99 (2002) 425-430
32. Barg A., Ossig R., Goerge T., Schneider M.F., Schillers H., Oberleithner H., et al. Soluble plasma-derived von Willebrand factor assembles to a haemostatically active filamentous network. Thromb Haemost 97 (2007) 514-526
33. Wu D., Vanhoorelbeke K., Cauwenberghs N., Meiring M., Depraetere H., Kotze H.F., et al. Inhibition of the von Willebrand (VWF)-collagen interaction by an antihuman VWF monoclonal antibody results in abolition of in vivo arterial platelet thrombus formation in baboons. Blood 99 (2002) 3623-3628
34. Bernardo A., Bergeron A.L., Sun C.W., Guchhait P., Cruz M.A., Lopez J.A., et al. Von Willebrand factor present in fibrillar collagen enhances platelet adhesion to collagen and collagen-induced platelet aggregation. J Thromb Haem 2 (2003) 660-669
35. Watson H.G., and Greaves M. Can we predict bleeding?. Semin Thromb Hemost 34 (2008) 97-103
36. Hoylaerts M.F. Platelet-vessel wall interactions in thrombosis and restenosis role of von Willebrand factor. Verh K Acad Geneeskd Belg 59 (1997) 161-183
37. Michiels J.J., Berneman Z., Gadisseur A., van der Planken M., Schroyens W., van de Velde A., et al. Classification and characterization of hereditary types 2A, 2B, 2C, 2D, 2E, 2M, 2N, and 2U (unclassifiable) von Willebrand disease. Clin Appl Thromb Hemost 12 (2006) 397-420