-
1
-
-
1642386264
-
Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model
-
Long BJ, Jelovac D, Handratta V, et al. Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model. J Natl Cancer Inst 2004; 96:456-465
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 456-465
-
-
Long, B.J.1
Jelovac, D.2
Handratta, V.3
-
2
-
-
0027173997
-
MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors
-
Yue W, Brodie A. MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors. J Steroid Biochem Mol Biol 1993; 44:671-673
-
(1993)
J Steroid Biochem Mol Biol
, vol.44
, pp. 671-673
-
-
Yue, W.1
Brodie, A.2
-
3
-
-
0027985528
-
A new nude mouse model for postmenopausal breast cancer using MCF-7 cells transfected with the human aromatase gene
-
Yue W, Zhou D, Chen S, et al. A new nude mouse model for postmenopausal breast cancer using MCF-7 cells transfected with the human aromatase gene. Cancer Res 1994; 54:5092-5095
-
(1994)
Cancer Res
, vol.54
, pp. 5092-5095
-
-
Yue, W.1
Zhou, D.2
Chen, S.3
-
4
-
-
0025089197
-
Stable expression of human aromatase complementary DNA in mammalian cells: A useful system for aromatase inhibitor screening
-
Zhou DJ, Pompon D, Chen SA. Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening. Cancer Res 1990; 50:6949-6954
-
(1990)
Cancer Res
, vol.50
, pp. 6949-6954
-
-
Zhou, D.J.1
Pompon, D.2
Chen, S.A.3
-
5
-
-
29544433211
-
A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
-
Breast International Group (BIG) 1-98 Collaborative Group [published erratum in: N Engl J Med 2006; 354:2200]
-
Breast International Group (BIG) 1-98 Collaborative Group, Thurlimann B, Keshaviah A, et al. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer [published erratum in: N Engl J Med 2006; 354:2200]. N Engl J Med 2005; 353:2747-2757
-
(2005)
N Engl J Med
, vol.353
, pp. 2747-2757
-
-
Thurlimann, B.1
Keshaviah, A.2
-
6
-
-
0037157603
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
-
[published erratum in: Lancet 2002 360:1520]
-
Baum M, Budzar AU, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial [published erratum in: Lancet 2002; 360:1520]. Lancet 2002; 359:2131-2139
-
(2002)
Lancet
, vol.359
, pp. 2131-2139
-
-
Baum, M.1
Budzar, A.U.2
Cuzick, J.3
-
7
-
-
33646789495
-
Preventing relapse beyond 5 years: The MA.17 extended adjuvant trial
-
Goss PE. Preventing relapse beyond 5 years: the MA.17 extended adjuvant trial. Semin Oncol 2006; 33(suppl 7):S8-12.
-
(2006)
Semin Oncol
, vol.33
, Issue.SUPPL. 7
-
-
Goss, P.E.1
-
8
-
-
24744450378
-
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17
-
Goss PE, Ingle JN, Martino S, et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. J Natl Cancer Inst 2005; 97:1262-1271
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1262-1271
-
-
Goss, P.E.1
Ingle, J.N.2
Martino, S.3
-
9
-
-
7444259675
-
A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
-
Goss PE, Ingle JN, Martino S, et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 2003; 349:1793-1802
-
(2003)
N Engl J Med
, vol.349
, pp. 1793-1802
-
-
Goss, P.E.1
Ingle, J.N.2
Martino, S.3
-
10
-
-
10744223655
-
A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
-
[published errata in: N Eng J Med 2004; 351:2461 and N Engl J Med 2006; 355:1746]
-
Coombes RC, Hall E, Gibson LJ, et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer [published errata in: N Eng J Med 2004; 351:2461 and N Engl J Med 2006; 355:1746]. N Engl J Med 2004; 350:1081-1092
-
(2004)
N Engl J Med
, vol.350
, pp. 1081-1092
-
-
Coombes, R.C.1
Hall, E.2
Gibson, L.J.3
-
11
-
-
0035992421
-
The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: Long-term studies using the intratumoral aromatase postmenopausal breast cancer model
-
Long BJ, Jelovac D, Thiantanawat A, et al. The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model. Clin Cancer Res 2002; 8:2378-2388
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2378-2388
-
-
Long, B.J.1
Jelovac, D.2
Thiantanawat, A.3
-
12
-
-
20644465808
-
Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole
-
Jelovac D, Sabnis G, Long BJ, et al. Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole. Cancer Res 2005; 65:5380-5389
-
(2005)
Cancer Res
, vol.65
, pp. 5380-5389
-
-
Jelovac, D.1
Sabnis, G.2
Long, B.J.3
-
13
-
-
60549089850
-
Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen
-
Sabnis G, Schayowitz A, Goloubeva O, et al. Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen. Cancer Res 2009; 69:1416-1428
-
(2009)
Cancer Res
, vol.69
, pp. 1416-1428
-
-
Sabnis, G.1
Schayowitz, A.2
Goloubeva, O.3
-
14
-
-
18144387234
-
The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation
-
Sabnis GJ, Jelovac D, Long B, et al. The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation. Cancer Res 2005; 65:3903-3910
-
(2005)
Cancer Res
, vol.65
, pp. 3903-3910
-
-
Sabnis, G.J.1
Jelovac, D.2
Long, B.3
-
15
-
-
49649112223
-
Stopping treatment can reverse acquired resistance to letrozole
-
Sabnis GJ, Macedo LF, Goloubeva O, et al. Stopping treatment can reverse acquired resistance to letrozole. Cancer Res 2008; 68:4518-4524
-
(2008)
Cancer Res
, vol.68
, pp. 4518-4524
-
-
Sabnis, G.J.1
MacEdo, L.F.2
Goloubeva, O.3
-
16
-
-
34249050833
-
Inhibition of the phosphatidylinositol 3-kinase/Akt pathway improves response of long-term estrogen-deprived breast cancer xenografts to antiestrogens
-
Sabnis G, Goloubeva O, Jelovac D, et al. Inhibition of the phosphatidylinositol 3-kinase/Akt pathway improves response of long-term estrogen-deprived breast cancer xenografts to antiestrogens. Clin Cancer Res 2007; 13:2751-2757
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2751-2757
-
-
Sabnis, G.1
Goloubeva, O.2
Jelovac, D.3
-
17
-
-
0032213907
-
The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity
-
Long BJ, Tilghman SL, Yue W, et al. The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity. J Steroid Biochem Mol Biol 1998; 67:293-304.
-
(1998)
J Steroid Biochem Mol Biol
, vol.67
, pp. 293-304
-
-
Long, B.J.1
Tilghman, S.L.2
Yue, W.3
-
18
-
-
0029032231
-
Effect of aromatase inhibitors on growth of mammary tumors in a nude mouse model
-
Yue W, Wang J, Savinov A, et al. Effect of aromatase inhibitors on growth of mammary tumors in a nude mouse model. Cancer Res 1995; 55:3073-3077
-
(1995)
Cancer Res
, vol.55
, pp. 3073-3077
-
-
Yue, W.1
Wang, J.2
Savinov, A.3
-
19
-
-
0028034674
-
Current perspectives on aromatase inhibitors in breast cancer
-
Goss PE, Gwyn KM. Current perspectives on aromatase inhibitors in breast cancer. J Clin Oncol 1994; 12:2460-2470
-
(1994)
J Clin Oncol
, vol.12
, pp. 2460-2470
-
-
Goss, P.E.1
Gwyn, K.M.2
-
20
-
-
23444458199
-
Adjuvant aromatase inhibitors for breast cancer
-
Howell A. Adjuvant aromatase inhibitors for breast cancer. Lancet 2005; 366:431-433
-
(2005)
Lancet
, vol.366
, pp. 431-433
-
-
Howell, A.1
-
21
-
-
66149116225
-
Trastuzumab improves the responsiveness of letrozole refractory human breast cancer cells to endocrine therapy
-
Presented at December 14-17, San Antonio, TX. Abstract 109
-
Sabnis G, Brodie A. Trastuzumab improves the responsiveness of letrozole refractory human breast cancer cells to endocrine therapy. Presented at: the 29th Annual San Antonio Breast Cancer Symposium; December 14-17, 2006; San Antonio, TX. Abstract 109.
-
(2006)
The 29th Annual San Antonio Breast Cancer Symposium
-
-
Sabnis, G.1
Brodie, A.2
-
22
-
-
84898702183
-
Trastuzumab increases sensitivity of hormone dependent and hormone refractory breast cancer cells to endocrine agents
-
Presented at April 14-18, Los Angeles, CA. Abstract 991
-
Sabnis GJ, Schayowitz A, Goloubeva O, et al. Trastuzumab increases sensitivity of hormone dependent and hormone refractory breast cancer cells to endocrine agents. Presented at: the 98th AACR Annual Meeting; April 14-18, 2007; Los Angeles, CA. Abstract 991.
-
(2007)
The 98th AACR Annual Meeting
-
-
Sabnis, G.J.1
Schayowitz, A.2
Goloubeva, O.3
-
23
-
-
0037241504
-
Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer
-
Johnston SR, Head J, Pancholi S, et al. Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. Clin Cancer Res 2003; 9:524S-32S.
-
(2003)
Clin Cancer Res
, vol.9
-
-
Johnston, S.R.1
Head, J.2
Pancholi, S.3
-
24
-
-
0242710208
-
Adaptive hypersensitivity following longterm estrogen deprivation: Involvement of multiple signal pathways
-
Yue W, Wang JP, Conaway MR, et al. Adaptive hypersensitivity following longterm estrogen deprivation: involvement of multiple signal pathways. J Steroid Biochem Mol Biol 2003; 86:265-274
-
(2003)
J Steroid Biochem Mol Biol
, vol.86
, pp. 265-274
-
-
Yue, W.1
Wang, J.P.2
Conaway, M.R.3
-
25
-
-
0036128068
-
The role of mitogen-activated protein (MAP) kinase in breast cancer
-
Santen RJ, Song RX, McPherson R, et al. The role of mitogen-activated protein (MAP) kinase in breast cancer. J Steroid Biochem Mol Biol 2002; 80:239-256
-
(2002)
J Steroid Biochem Mol Biol
, vol.80
, pp. 239-256
-
-
Santen, R.J.1
Song, R.X.2
McPherson, R.3
-
26
-
-
0034464912
-
Estradiol hypersensitivity and mitogen- activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo
-
Shim WS, Conaway M, Masamura S, et al. Estradiol hypersensitivity and mitogen- activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo. Endocrinology 2000; 141:396-405.
-
(2000)
Endocrinology
, vol.141
, pp. 396-405
-
-
Shim, W.S.1
Conaway, M.2
Masamura, S.3
-
27
-
-
12144269500
-
Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer
-
Osborne CK, Shou J, Massarweh S, et al. Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer. Clin Cancer Res 2005; 11:865s-70s.
-
(2005)
Clin Cancer Res
, vol.11
-
-
Osborne, C.K.1
Shou, J.2
Massarweh, S.3
-
28
-
-
0034899503
-
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells
-
Oh AS, Lorant LA, Holloway JN, et al. Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells. Mol Endocrinol 2001; 15:1344-1359
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1344-1359
-
-
Oh, A.S.1
Lorant, L.A.2
Holloway, J.N.3
-
29
-
-
33645730357
-
Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors
-
Creighton CJ, Hilger AM, Murthy S, et al. Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors. Cancer Res 2006; 66:3903-3911
-
(2006)
Cancer Res
, vol.66
, pp. 3903-3911
-
-
Creighton, C.J.1
Hilger, A.M.2
Murthy, S.3
-
30
-
-
0035664786
-
Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer
-
discussion 4411s-4412s
-
Kurokawa H, Arteaga CL. Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer. Clin Cancer Res 2001; 7(12 suppl):4436s-4442s; discussion 4411s-4412s.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.12 SUPPL.
-
-
Kurokawa, H.1
Arteaga, C.L.2
-
31
-
-
24644453938
-
In vitro and in vivo effects of combination of Trastuzumab (Herceptin) and Tamoxifen in breast cancer
-
Wang CX, Koay DC, Edwards A, et al. In vitro and in vivo effects of combination of Trastuzumab (Herceptin) and Tamoxifen in breast cancer. Breast Cancer Res Treat 2005; 92:251-263
-
(2005)
Breast Cancer Res Treat
, vol.92
, pp. 251-263
-
-
Wang, C.X.1
Koay, D.C.2
Edwards, A.3
-
32
-
-
2942652871
-
Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
-
Shou J, Massarweh S, Osborne CK, et al. Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 2004; 96:926-935
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 926-935
-
-
Shou, J.1
Massarweh, S.2
Osborne, C.K.3
-
33
-
-
38549147013
-
Enhancing endocrine response with novel targeted therapies: Why have the clinical trials to date failed to deliver on the preclinical promise?
-
Johnston SR, Leary A, Martin LA, et al. Enhancing endocrine response with novel targeted therapies: why have the clinical trials to date failed to deliver on the preclinical promise? Cancer 2008; 112(3 suppl):710-717
-
(2008)
Cancer
, vol.112
, Issue.3 SUPPL.
, pp. 710-717
-
-
Johnston, S.R.1
Leary, A.2
Martin, L.A.3
|