Inhibition of the phosphatidylinositol 3-kinase/Akt pathway improves response of long-term estrogen-deprived breast cancer xenografts to antiestrogens

Clinical Cancer Research

Volumn 13, Issue 9, 2007, Pages 2751-2757

  Sabnis, Gauri ^a   Goloubeva, Olga ^a   Jelovac, Danijela ^a   Schayowitz, Adam ^a   Brodie, Angela ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; AROMATASE INHIBITOR; ESTROGEN; FULVESTRANT; LETROZOLE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; TAMOXIFEN; WORTMANNIN;

ARTICLE; BREAST CANCER; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; XENOGRAFT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANDROSTENEDIONE; ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AROMATASE INHIBITORS; BREAST NEOPLASMS; CELL LINE, TUMOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; HUMANS; MICE; MICE, NUDE; NITRILES; PROTO-ONCOGENE PROTEINS C-AKT; TAMOXIFEN; TRIAZOLES;

EID: 34249050833     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-2466     Document Type: Article

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