Synthesis of β-aminoketones and construction of highly substituted 4-piperidones by mannich reaction induced by persistent radical cation salts

Organic Letters

Volumn 12, Issue 4, 2010, Pages 732-735

  Jia, Xiao Dong ^a,b,c   Wang, Xiao E ^a   Yang, Cai Xia ^a   Huo, Cong De ^a   Wang, Wen Juan ^a   Ren, Yan ^a   Wang, Xi Cun ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b NORTHWEST NORMAL UNIVERSITY   (China)

^c LANZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 76849109045     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol9027978     Document Type: Article

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44. This is because when two moles of imines was added extra solvent must be added to permit sufficient agitation, and the concentration of ketone is too low to efficiently trap the iminium radical cation, producing a greatly reduced yield.