Selective cell affinity of biomimetic micro-nano-hybrid structured TiO2 overcomes the biological dilemma of osteoblasts

Dental Materials

Volumn 26, Issue 4, 2010, Pages 275-287

  Hori, Norio ^a   Iwasa, Fuminori ^a   Ueno, Takeshi ^a   Takeuchi, Kazuo ^b   Tsukimura, Naoki ^a   Yamada, Masahiro ^a   Hattori, Masami ^b   Yamamoto, Akiko ^c   Ogawa, Takahiro ^a  

^a UCLA SCHOOL OF DENTISTRY   (United States)

^b AICHI GAKUIN UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR MATERIALS SCIENCE   (Japan)

Author keywords

Biomimetics; Functionalization; Nanonodules; Nanotechnology; Self assembly; Titanium dental implants

Indexed keywords

BIOLOGICAL AGENTS; BONE INTEGRATION; CELL AFFINITY; COMMERCIALLY PURE TITANIUMS; DENTAL IMPLANTS; ETCHED SURFACE; FUNCTIONALIZATION; FUNCTIONALIZATIONS; FUNCTIONALIZED; HEALING TIME; HIERARCHICAL PLATFORMS; HYBRID SURFACE; INHIBITORY MECHANISM; INVERSE CORRELATION; MICRO-NANO; MICRO-TEXTURE; MICROPITS; NANO SCALE; NANOFEATURES; OSTEOBLAST PROLIFERATION; PERI-IMPLANT BONES; RAT BONE MARROW; REGULATORY EFFECTS; SMOOTH SURFACE; TIO; TITANIUM DENTAL IMPLANTS; TITANIUM DISKS; TITANIUM SURFACES;

ACIDS; BIOLOGICAL MATERIALS; BIOMATERIALS; BIOMIMETICS; BONE; CELL CULTURE; DISKS (MACHINE COMPONENTS); DISKS (STRUCTURAL COMPONENTS); FIBROBLASTS; NANOTECHNOLOGY; OSTEOBLASTS; SELF ASSEMBLY; SURFACE ROUGHNESS; TITANIUM;

DENTAL PROSTHESES;

BIOMIMETIC MATERIAL; COLLAGEN; NANOMATERIAL; OSTEOCALCIN; OSTEOPONTIN; TITANIUM; TITANIUM DIOXIDE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN 3T3; CHEMISTRY; CYTOLOGY; DENTAL ACID ETCHING; FIBROBLAST; METABOLISM; MOUSE; OSTEOBLAST; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; SURFACE PROPERTY;

3T3 CELLS; ACID ETCHING, DENTAL; ANIMALS; BIOMIMETIC MATERIALS; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; FIBROBLASTS; MICE; NANOSTRUCTURES; OSTEOBLASTS; OSTEOCALCIN; OSTEOPONTIN; RATS; RATS, SPRAGUE-DAWLEY; SURFACE PROPERTIES; TITANIUM;

EID: 76849096618     PISSN: 01095641     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dental.2009.11.077     Document Type: Article

References (58)

1. Masuda T., Yliheikkila P.K., Felton D.A., and Cooper L.F. Generalizations regarding the process and phenomenon of osseointegration. Part I. In vivo studies. Int J Oral Maxillofac Implants 13 (1998) 17-29
2. Brunski J.B., Puleo D.A., and Nanci A. Biomaterials and biomechanics of oral and maxillofacial implants: current status and future developments. Int J Oral Maxillofac Implants 15 (2000) 15-46
3. Zinger O., Zhao G., Schwartz Z., Simpson J., Wieland M., Landolt D., et al. Differential regulation of osteoblasts by substrate microstructural features. Biomaterials 26 (2005) 1837-1847
4. Olivares-Navarrete R., Raz P., Zhao G., Chen J., Wieland M., Cochran D.L., et al. Integrin alpha2beta1 plays a critical role in osteoblast response to micron-scale surface structure and surface energy of titanium substrates. Proc Natl Acad Sci USA 105 (2008) 15767-15772
5. Albrektsson T., and Wennerberg A. Oral implant surfaces: Part 1-review focusing on topographic and chemical properties of different surfaces and in vivo responses to them. Int J Prosthodont 17 (2004) 536-543
6. Takeuchi K., Saruwatari L., Nakamura H.K., Yang J.M., and Ogawa T. Enhanced intrinsic biomechanical properties of osteoblastic mineralized tissue on roughened titanium surface. J Biomed Mater Res A 72A (2005) 296-305
7. Kubo K., Att W., Yamada M., Ohmi K., Tsukimura N., Suzuki T., et al. Microtopography of titanium suppresses osteoblastic differentiation but enhances chondroblastic differentiation of rat femoral periosteum-derived cells. J Biomed Mater Res A 87 (2008) 380-391
8. Matsuzaka K., Walboomers F., de Ruijter A., and Jansen J.A. Effect of microgrooved poly-l-lactic (PLA) surfaces on proliferation, cytoskeletal organization, and mineralized matrix formation of rat bone marrow cells. Clin Oral Implants Res 11 (2000) 325-333
9. Boyan B.D., Hummert T.W., Dean D.D., and Schwartz Z. Role of material surfaces in regulating bone and cartilage cell response. Biomaterials 17 (1996) 137-146
10. Wennerberg A., and Albrektsson T. Suggested guidelines for the topographic evaluation of implant surfaces. Int J Oral Maxillofac Implants 15 (2000) 331-344
11. Cooper L.F., Masuda T., Yliheikkila P.K., and Felton D.A. Generalizations regarding the process and phenomenon of osseointegration. Part II. In vitro studies. Int J Oral Maxillofac Implants 13 (1998) 163-174
12. Ogawa T., and Nishimura I. Genes differentially expressed in titanium implant healing. J Dent Res 85 (2006) 566-570
13. Albrektsson T., and Wennerberg A. Oral implant surfaces: Part 2--review focusing on clinical knowledge of different surfaces. Int J Prosthodont 17 (2004) 544-564
14. Stein G.S., and Lian J.B. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr Rev 14 (1993) 424-442
15. Siddhanti S.R., and Quarles L.D. Molecular to pharmacologic control of osteoblast proliferation and differentiation. J Cell Biochem 55 (1994) 310-320
16. Alborzi A., Mac K., Glackin C.A., Murray S.S., and Zernik J.H. Endochondral and intramembranous fetal bone development: osteoblastic cell proliferation, and expression of alkaline phosphatase, m-twist, and histone H4. J Craniofac Genet Dev Biol 16 (1996) 94-106
17. Owen T.A., Aronow M., Shalhoub V., Barone L.M., Wilming L., Tassinari M.S., et al. Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J Cell Physiol 143 (1990) 420-430
18. Spinella-Jaegle S., Roman-Roman S., Faucheu C., Dunn F.W., Kawai S., Gallea S., et al. Opposite effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on osteoblast differentiation. Bone 29 (2001) 323-330
19. Alliston T., Choy L., Ducy P., Karsenty G., and Derynck R. TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. EMBO J 20 (2001) 2254-2272
20. Ogawa T., Sukotjo C., and Nishimura I. Modulated bone matrix-related gene expression is associated with differences in interfacial strength of different implant surface roughness. J Prosthodont 11 (2002) 241-247
21. Ogawa T., and Nishimura I. Different bone integration profiles of turned and acid-etched implants associated with modulated expression of extracellular matrix genes. Int J Oral Maxillofac Implants 18 (2003) 200-210
22. Bachle M., and Kohal R.J. A systematic review of the influence of different titanium surfaces on proliferation, differentiation and protein synthesis of osteoblast-like MG63 cells. Clin Oral Implants Res 15 (2004) 683-692
23. Zhao G., Schwartz Z., Wieland M., Rupp F., Geis-Gerstorfer J., Cochran D.L., et al. High surface energy enhances cell response to titanium substrate microstructure. J Biomed Mater Res A 74 (2005) 49-58
24. Boyan B.D., Bonewald L.F., Paschalis E.P., Lohmann C.H., Rosser J., Cochran D.L., et al. Osteoblast-mediated mineral deposition in culture is dependent on surface microtopography. Calcif Tissue Int 71 (2002) 519-529
25. Lu L., Yaszemski M.J., and Mikos A.G. TGF-beta1 release from biodegradable polymer microparticles: its effects on marrow stromal osteoblast function. J Bone Joint Surg Am 83-A Suppl. 1 (2001) S82-S91
26. Bonewald L.F., and Dallas S.L. Role of active and latent transforming growth factor beta in bone formation. J Cell Biochem 55 (1994) 350-357
27. Centrella M., Horowitz M.C., Wozney J.M., and McCarthy T.L. Transforming growth factor-beta gene family members and bone. Endocr Rev 15 (1994) 27-39
28. Sanchez C., Arribart H., and Guille M.M. Biomimetism and bioinspiration as tools for the design of innovative materials and systems. Nat Mater 4 (2005) 277-288
29. Tamerler C., and Sarikaya M. Molecular biomimetics: utilizing nature's molecular ways in practical engineering. Acta Biomater 3 (2007) 289-299
30. Fantner G.E., Hassenkam T., Kindt J.H., Weaver J.C., Birkedal H., Pechenik L., et al. Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture. Nat Mater 4 (2005) 612-616
31. Tai K., Dao M., Suresh S., Palazoglu A., and Ortiz C. Nanoscale heterogeneity promotes energy dissipation in bone. Nat Mater 6 (2007) 454-462
32. Balasundaram G., and Webster T.J. Nanotechnology and biomaterials for orthopedic medical applications. Nanomedicine 1 (2006) 169-176
33. Dalby M.J., Gadegaard N., Curtis A.S., and Oreffo R.O. Nanotopographical control of human osteoprogenitor differentiation. Curr Stem Cell Res Ther 2 (2007) 129-138
34. Smith L.J., Swaim J.S., Yao C., Haberstroh K.M., Nauman E.A., and Webster T.J. Increased osteoblast cell density on nanostructured PLGA-coated nanostructured titanium for orthopedic applications. Int J Nanomed 2 (2007) 493-499
35. Variola F., Yi J.H., Richert L., Wuest J.D., Rosei F., and Nanci A. Tailoring the surface properties of Ti6Al4V by controlled chemical oxidation. Biomaterials 29 (2008) 1285-1298
36. Dalby M.J., McCloy D., Robertson M., Agheli H., Sutherland D., Affrossman S., et al. Osteoprogenitor response to semi-ordered and random nanotopographies. Biomaterials 27 (2006) 2980-2987
37. Sarikaya M., Tamerler C., Jen A.K., Schulten K., and Baneyx F. Molecular biomimetics: nanotechnology through biology. Nat Mater 2 (2003) 577-585
38. Dalby M.J., Gadegaard N., Tare R., Andar A., Riehle M.O., Herzyk P., et al. The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater 6 (2007) 997-1003
39. Lim J.Y., and Donahue H.J. Cell sensing and response to micro- and nanostructured surfaces produced by chemical and topographic patterning. Tissue Eng 13 (2007) 1879-1891
40. Ogawa T., Saruwatari L., Takeuchi K., Aita H., and Ohno N. Ti nano-nodular structuring for bone integration and regeneration. J Dent Res 87 (2008) 751-756
41. Aita H., Hori N., Takeuchi M., Suzuki T., Yamada M., Anpo M., et al. The effect of ultraviolet functionalization of titanium on integration with bone. Biomaterials 30 (2009) 1015-1025
42. Hori N., Att W., Ueno T., Sato N., Yamada M., Saruwatari L., et al. Age-dependent degradation of protein adsorption capacity of Ti. J Dent Res 88 (2009) 663-667
43. Suzuki T, Hori N, Att W, Kubo K, Iwasa F, Ueno T, et al. UV treatment overcomes time-related degrading bioactivity of titanium. Tissue Eng Part A Epub ahead of print, doi: 10.1089/ten.TEA.2008.0568.
44. Saruwatari L., Aita H., Butz F., Nakamura H.K., Ouyang J., Yang Y., et al. Osteoblasts generate harder, stiffer, and more delamination-resistant mineralized tissue on titanium than on polystyrene, associated with distinct tissue micro- and ultrastructure. J Bone Miner Res 20 (2005) 2002-2016
45. Kessler G., and Wolfman M. An automated procedure for the simultaneous determination of calcium and phosphorus. Clin Chem 10 (1964) 686-703
46. Dieudonne S.C., van den Dolder J., de Ruijter J.E., Paldan H., Peltola T., van't Hof M.A., et al. Osteoblast differentiation of bone marrow stromal cells cultured on silica gel and sol-gel-derived titania. Biomaterials 23 (2002) 3041-3051
47. Tullberg-Reinert H., and Jundt G. In situ measurement of collagen synthesis by human bone cells with a sirius red-based colorimetric microassay: effects of transforming growth factor beta2 and ascorbic acid 2-phosphate. Histochem Cell Biol 112 (1999) 271-276
48. Woo K.M., Seo J., Zhang R., and Ma P.X. Suppression of apoptosis by enhanced protein adsorption on polymer/hydroxyapatite composite scaffolds. Biomaterials 28 (2007) 2622-2630
49. Mata A., Su X., Fleischman A.J., Roy S., Banks B.A., Miller S.K., et al. Osteoblast attachment to a textured surface in the absence of exogenous adhesion proteins. IEEE Trans Nanobiosci 2 (2003) 287-294
50. Dalby M.J., McCloy D., Robertson M., Wilkinson C.D., and Oreffo R.O. Osteoprogenitor response to defined topographies with nanoscale depths. Biomaterials 27 (2006) 1306-1315
51. Dalby M.J., Gadegaard N., and Wilkinson C.D. The response of fibroblasts to hexagonal nanotopography fabricated by electron beam lithography. J Biomed Mater Res A 84 (2008) 973-979
52. Seunarine K., Curtis A., Meredith D., Wilkinson C., Riehle M., and Gadegaard N. A hierarchical response of cells to perpendicular micro- and nanometric textural cues. IEEE Trans Nanobiosci (2009)
53. LeGeros R.Z., and Craig R.G. Strategies to affect bone remodeling: osteointegration. J Bone Miner Res 8 Suppl. 2 (1993) S583-S596
54. Puleo D.A., and Nanci A. Understanding and controlling the bone-implant interface. Biomaterials 20 (1999) 2311-2321
55. Pilliar R.M. Cementless implant fixation-toward improved reliability. Orthop Clin North Am 36 (2005) 113-119
56. Ogawa T., Ozawa S., Shih J.H., Ryu K.H., Sukotjo C., Yang J.M., et al. Biomechanical evaluation of osseous implants having different surface topographies in rats. J Dent Res 79 (2000) 1857-1863
57. Klokkevold P.R., Johnson P., Dadgostari S., Caputo A., Davies J.E., and Nishimura R.D. Early endosseous integration enhanced by dual acid etching of titanium: a torque removal study in the rabbit. Clin Oral Implants Res 12 (2001) 350-357
58. Att W., Hori N., Takeuchi M., Ouyang J., Yang Y., Anpo M., et al. Time-dependent degradation of titanium osteoconductivity: an implication of biological aging of implant materials. Biomaterials 30 (2009) 5352-5363