Metabolomic investigation of gastric cancer tissue using gas chromatography/mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 396, Issue 4, 2010, Pages 1385-1395

  Wu, Hao ^a   Xue, Ruyi ^a   Tang, Zhaoqing ^a   Deng, Chunhui ^a   Liu, Taotao ^a   Zeng, Huazong ^b   Sun, Yihong ^a   Shen, Xizhong ^a  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Foundation Engineering Co Ltd   (China)

Author keywords

Biomarker; Gas chromatography mass spectrometry; Gastric cancer; Metabolomic profile

Indexed keywords

AREA UNDER THE CURVES; CHEMICAL DERIVATIZATION; CLINICAL DIAGNOSIS; DIAGNOSTIC MODEL; GAS CHROMATOGRAPHY/MASS SPECTROMETRY; GASTRIC CANCERS; GASTRIC MUCOSA; GASTRIC TISSUE; INVASIVE TUMORS; MALIGNANT TISSUES; METABOLOMIC PROFILE; METABOLOMICS; NON-INVASIVE; RECEIVER OPERATING CHARACTERISTICS; WILCOXON RANK SUM TEST;

BIOMARKERS; BIOMOLECULES; DIAGNOSIS; HISTOLOGY; METABOLISM; METABOLITES; ONCOLOGY; SPECTROMETRY; TUMORS;

PRINCIPAL COMPONENT ANALYSIS;

TUMOR MARKER;

ADULT; AGED; ARTICLE; CHEMISTRY; FEMALE; HUMAN; MALE; MASS FRAGMENTOGRAPHY; METABOLISM; METABOLOMICS; MIDDLE AGED; STANDARD; STOMACH; STOMACH TUMOR;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MALE; METABOLOMICS; MIDDLE AGED; REFERENCE STANDARDS; STOMACH; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 76749168026     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-009-3317-4     Document Type: Article

References (45)

1. DM Parkin F Bray J Ferlay P Pisani 2005 Global cancer statistics, 2002 CA Cancer J Clin 55 74 108 10.3322/canjclin.55.2.74
2. KD Crew AI Neugut 2006 Epidemiology of gastric cancer World J Gastroenterol 12 354 362
3. JS Macdonald 2006 Gastric cancer-new therapeutic options N Engl J Med 355 76 77 10.1056/NEJMe068121 1:CAS:528:DC%2BD28Xms1Gkt78%3D (Pubitemid 43053709)
4. D Cunningham YJ Chua 2007 East meets west in the treatment of gastric cancer N Engl J Med 357 1863 1865 10.1056/NEJMe078182 1:CAS:528: DC%2BD2sXht1Kiur%2FM (Pubitemid 350044810)
5. W Yasui N Oue PP Aung S Matsumura M Shutoh H Nakayama 2005 Molecular-pathological prognostic factors of gastric cancer: a review Gastric Cancer 8 86 94 10.1007/s10120-005-0320-0 1:CAS:528:DC%2BD2MXjvVCntbY%3D (Pubitemid 40655517)
6. A Tashiro M Sano K Kinameri K Fujita Y Takeuchi 2006 Comparing mass screening techniques for gastric cancer in Japan World J Gastroenterol 12 4873 4874
7. P Sipponen P Ranta T Helske I Kaariainen T Maki A Linnala O Suovaniemi A Alanko M Harkonen 2002 Serum levels of amidated gastrin-17 and pepsinogen I in atrophic gastritis: an observational case-control study Scand J Gastroenterol 37 785 791 1:CAS:528:DC%2BD38XmvVSkt7s%3D
8. H Vaananen M Vauhkonen T Helske I Kaariainen M Rasmussen H Tunturi-Hihnala J Koskenpato M Sotka M Turunen R Sandstrom M Ristikankare A Jussila P Sipponen 2003 Non-endoscopic diagnosis of atrophic gastritis with a blood test. Correlation between gastric histology and serum levels of gastrin-17 and pepsinogen I: a multicentre study Eur J Gastroenterol Hepatol 15 885 891 10.1097/00042737-200308000-00009 1:STN:280:DC%2BD3sznvVWjtQ%3D%3D
9. K Miki M Morita M Sasajima R Hoshina E Kanda Y Urita 2003 Usefulness of gastric cancer screening using the serum pepsinogen test method Am J Gastroenterol 98 735 739 10.1111/j.1572-0241.2003.07410.x (Pubitemid 36576295)
10. F Kitahara K Kobayashi T Sato Y Kojima T Araki MA Fujino 1999 Accuracy of screening for gastric cancer using serum pepsinogen concentrations Gut 44 693 697 1:STN:280:DyaK1M3itFKrug%3D%3D
11. S Kikuchi M Kurosawa T Sakiyama H Tenjin K Miki O Wada Y Inaba 2000 Long-term effect of Helicobacter pylori infection on serum pepsinogens Jpn J Cancer Res 91 471 476 1:CAS:528:DC%2BD3cXjsleqtrY%3D
12. WK Leung MS Wu Y Kakugawa JJ Kim KG Yeoh KL Goh KC Wu DC Wu J Sollano U Kachintorn T Gotoda JT Lin WC You EK Ng JJ Sung 2008 Screening for gastric cancer in Asia: current evidence and practice Lancet Oncol 9 279 287 10.1016/S1470-2045(08)70072-X (Pubitemid 351722947)
13. M Mal PK Koh PY Cheah EC Chan 2009 Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue Rapid Commun Mass Spectrom 23 487 494 10.1002/rcm.3898 1:CAS:528:DC%2BD1MXitVakt70%3D
14. AA Evans G Chen EA Ross FM Shen WY Lin WT London 2002 Eight-year follow-up of the 90, 000-person Haimen City cohort: I. Hepatocellular carcinoma mortality, risk factors, and gender differences Cancer Epidemiol Biomarkers Prev 11 369 376
15. WM Claudino A Quattrone L Biganzoli M Pestrin I Bertini A Di Leo 2007 Metabolomics: available results, current research projects in breast cancer, and future applications J Clin Oncol 25 2840 2846 10.1200/JCO.2006.09.7550 1:CAS:528:DC%2BD2sXosValtbY%3D (Pubitemid 47123194)
16. WR Wikoff JA Gangoiti BA Barshop G Siuzdak 2007 Metabolomics identifies perturbations in human disorders of propionate metabolism Clin Chem 53 2169 2176 10.1373/clinchem.2007.089011 1:CAS:528:DC%2BD2sXhtl2qt77P (Pubitemid 350197301)
17. C Deng N Li X Zhang 2004 Development of headspace solid-phase microextraction with on-fiber derivatization for determination of hexanal and heptanal in human blood J Chromatogr B Analyt Technol Biomed Life Sci 813 47 52 10.1016/j.jchromb.2004.09.007 1:CAS:528:DC%2BD2cXhtVSns7vK (Pubitemid 39535427)
18. R Xue Z Lin C Deng L Dong T Liu J Wang X Shen 2008 A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry Rapid Commun Mass Spectrom 22 3061 3068 10.1002/rcm.3708 1:CAS:528:DC%2BD1cXht1ekt7nK
19. M Bogdanov WR Matson L Wang T Matson R Saunders-Pullman SS Bressman M Flint Beal 2008 Metabolomic profiling to develop blood biomarkers for Parkinson's disease Brain 131 389 396 10.1093/brain/awm304 (Pubitemid 351197614)
20. J Chen X Zhao J Fritsche P Yin P Schmitt-Kopplin W Wang X Lu HU Haring ED Schleicher R Lehmann G Xu 2008 Practical approach for the identification and isomer elucidation of biomarkers detected in a metabonomic study for the discovery of individuals at risk for diabetes by integrating the chromatographic and mass spectrometric information Anal Chem 80 1280 1289 10.1021/ac702089h 1:CAS:528:DC%2BD1cXlsl2hug%3D%3D (Pubitemid 351272366)
21. H Wu R Xue C Lu C Deng T Liu H Zeng Q Wang X Shen 2009 Metabolomic study for diagnostic model of oesophageal cancer using gas chromatography/mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 877 3111 3117 10.1016/j.jchromb.2009.07.039 1:CAS:528:DC%2BD1MXhtFams7jP
22. C Deng X Zhang N Li 2004 Investigation of volatile biomarkers in lung cancer blood using solid-phase microextraction and capillary gas chromatography-mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 808 269 277 10.1016/j.jchromb.2004.05.015 1:CAS:528:DC%2BD2cXlvVSrtrs%3D (Pubitemid 38952922)
23. JK Nicholson J Connelly JC Lindon E Holmes 2002 Metabonomics: a platform for studying drug toxicity and gene function Nat Rev Drug Discov 1 153 161 10.1038/nrd728 1:CAS:528:DC%2BD38Xhs1aksbw%3D (Pubitemid 41646523)
24. P Jonsson J Gullberg A Nordstrom M Kusano M Kowalczyk M Sjostrom T Moritz 2004 A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS Anal Chem 76 1738 1745 10.1021/ac0352427 1:CAS:528:DC%2BD2cXhtVylsLw%3D (Pubitemid 38338423)
25. P Jonsson AI Johansson J Gullberg J Trygg A Jiye B Grung S Marklund M Sjostrom H Antti T Moritz 2005 High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses Anal Chem 77 5635 5642 10.1021/ac050601e 1:CAS:528:DC%2BD2MXmvFSrsr0%3D (Pubitemid 41268639)
26. C Deng J Zhang X Yu W Zhang X Zhang 2004 Determination of acetone in human breath by gas chromatography-mass spectrometry and solid-phase microextraction with on-fiber derivatization J Chromatogr B Analyt Technol Biomed Life Sci 810 269 275 1:CAS:528:DC%2BD2cXnslehsr0%3D (Pubitemid 39243314)
27. LH Sobin ID Fleming 1997 TNM Classification of Malignant Tumors, 5th edn (1997). Union Internationale Contre le Cancer and the American Joint Committee on Cancer Cancer 80 1803 1804 10.1002/(SICI)1097-0142(19971101)80:9<1803:: AID-CNCR16>3.0.CO;2-9 1:STN:280:DyaK1c%2FhtF2itA%3D%3D (Pubitemid 27475940)
28. EC Chan PK Koh M Mal PY Cheah KW Eu A Backshall R Cavill JK Nicholson HC Keun 2009 Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS) J Proteome Res 8 352 361 10.1021/pr8006232 1:CAS:528:DC%2BD1cXhsVOnsLnN
29. CY Lin HF Wu RS Tjeerdema MR Viant 2007 Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics Metabolomics 3 55 67 10.1007/s11306-006-0043-1 1:CAS:528:DC%2BD2sXktVOhu70%3D (Pubitemid 46443556)
30. HK Kim YH Choi TJ Luijendijk RA Rocha R Verpoorte 2004 Comparison of extraction methods for secologanin and the quantitative analysis of secologanin from Symphoricarpos albus using 1H-NMR Phytochem Anal 15 257 261 10.1002/pca.776 1:CAS:528:DC%2BD2cXms1Gnurk%3D (Pubitemid 39136526)
31. R Xue L Dong H Wu T Liu J Wang X Shen 2009 Gas chromatography/mass spectrometry screening of serum metabolomic biomarkers in hepatitis B virus infected cirrhosis patients Clin Chem Lab Med 47 305 310 10.1515/CCLM.2009.083 1:CAS:528:DC%2BD1MXktlaltb8%3D
32. H Wu R Xue L Dong T Liu C Deng H Zeng X Shen 2009 Metabolomic profiling of human urine in hepatocellular carcinoma patients using gas chromatography/mass spectrometry Anal Chim Acta 648 98 104 10.1016/j.aca.2009. 06.033 1:CAS:528:DC%2BD1MXoslGnsbo%3D
33. P Jonsson SJ Bruce T Moritz J Trygg M Sjostrom R Plumb J Granger E Maibaum JK Nicholson E Holmes H Antti 2005 Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets Analyst 130 701 707 10.1039/b501890k 1:CAS:528:DC%2BD2MXjsFOnurc%3D (Pubitemid 40685900)
34. J Trygg E Holmes T Lundstedt 2007 Chemometrics in metabonomics J Proteome Res 6 469 479 10.1021/pr060594q 1:CAS:528:DC%2BD28XhtlCit7rM (Pubitemid 46340151)
35. C Postic R Dentin J Girard 2004 Role of the liver in the control of carbohydrate and lipid homeostasis Diabetes Metab 30 398 408 10.1016/S1262-3636(07)70133-7 1:CAS:528:DC%2BD2MXlsFeitbc%3D
36. ML Anthony VS Rose JK Nicholson JC Lindon 1995 Classification of toxin-induced changes in 1H NMR spectra of urine using an artificial neural network J Pharm Biomed Anal 13 205 211 10.1016/0731-7085(95)01278-S 1:CAS:528:DyaK2MXltFGqtrw%3D
37. O Beckonert ME Bollard TMD Ebbels HC Keun H Antti E Holmes JC Lindon JK Nicholson 2003 Anal Chim Acta 490 3 10.1016/S0003-2670(03)00060-6 1:CAS:528:DC%2BD3sXmsVOlsb0%3D (Pubitemid 37281288)
38. A Hirayama K Kami M Sugimoto M Sugawara N Toki H Onozuka T Kinoshita N Saito A Ochiai M Tomita H Esumi T Soga 2009 Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry Cancer Res 69 4918 4925 10.1158/0008-5472.CAN- 08-4806 1:CAS:528:DC%2BD1MXmsFGks74%3D
39. K Taniguchi T Nonami A Nakao A Harada T Kurokawa S Sugiyama N Fujitsuka Y Shimomura SM Hutson RA Harris H Takagi 1996 The valine catabolic pathway in human liver: effect of cirrhosis on enzyme activities Hepatology 24 1395 1398 10.1002/hep.510240614 1:CAS:528:DyaK2sXpt1CmtA%3D%3D
40. K Ishigure Y Shimomura T Murakami T Kaneko S Takeda S Inoue S Nomoto K Koshikawa T Nonami A Nakao 2001 Human liver disease decreases methacrylyl-CoA hydratase and beta-hydroxyisobutyryl-CoA hydrolase activities in valine catabolism Clin Chim Acta 312 115 121 10.1016/S0009-8981(01)00597-6 1:CAS:528:DC%2BD3MXnt1Whs7s%3D (Pubitemid 32913587)
41. AM Landel WG Hammond MM Meguid 1985 Aspects of amino acid and protein metabolism in cancer-bearing states Cancer 55 230 237 10.1002/1097- 0142(19850101)55:1+<230::AID-CNCR2820551305>3.0.CO;2-I 1:CAS:528:DyaL2MXht12ltL8%3D
42. 3 on liver and kidney tissues by magic-angle spinning 1H nuclear magnetic resonance spectroscopy and pattern recognition Anal Biochem 339 242 248 10.1016/j.ab.2005.01.021 1:CAS:528:DC%2BD2MXis1Gksbs%3D (Pubitemid 40395281)
43. NJ Waters E Holmes CJ Waterfield RD Farrant JK Nicholson 2002 NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate Biochem Pharmacol 64 67 77 10.1016/S0006-2952(02)01016-X 1:CAS:528:DC%2BD38XltFSqs7s%3D (Pubitemid 34775177)
44. Y Yang C Li X Nie X Feng W Chen Y Yue H Tang F Deng 2007 Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-angle spinning 1H NMR spectroscopy in conjunction with multivariate data analysis J Proteome Res 6 2605 2614 10.1021/pr070063h 1:CAS:528:DC%2BD2sXmtlOnurk%3D (Pubitemid 47122355)
45. WL Cheng CS Wang YH Huang Y Liang PY Lin C Hsueh YC Wu WJ Chen CJ Yu SR Lin KH Lin 2008 Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer Int J Cancer 123 1787 1796 10.1002/ijc.23746 1:CAS:528:DC%2BD1cXhtFKhu7nF