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Volumn 159, Issue 1, 2010, Pages 517-527

The Role of VEGF Pathways in Human Physiologic and Pathologic Angiogenesis

Author keywords

angiogenesis; human; mechanisms; platelet derived growth factor (PDGF); tyrosine kinases; vascular endothelial growth factor (VEGF); VEGF receptors

Indexed keywords

BEVACIZUMAB; FIBRIN; IMC 1121; IMC 18F1; THROMBIN; UNCLASSIFIED DRUG; VASCULOTROPIN 165; VASCULOTROPIN INHIBITOR; VATALANIB;

EID: 76749160237     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.12.014     Document Type: Article
Times cited : (23)

References (32)
  • 1
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol 29 6 Suppl. 16 (2002) 15
    • (2002) Semin Oncol , vol.29 , Issue.6 SUPPL. 16 , pp. 15
    • Folkman, J.1
  • 2
    • 27644584796 scopus 로고    scopus 로고
    • Update on angiogenesis inhibitors
    • Zakarija A., and Soff G. Update on angiogenesis inhibitors. Curr Opin Oncol 17 (2005) 578
    • (2005) Curr Opin Oncol , vol.17 , pp. 578
    • Zakarija, A.1    Soff, G.2
  • 3
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N., Gerber H.P., and LeCouter J. The biology of VEGF and its receptors. Nat Med 9 (2003) 669
    • (2003) Nat Med , vol.9 , pp. 669
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 4
    • 0027053487 scopus 로고
    • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    • Pepper M.S., Ferrara N., Orci L., et al. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun 189 (1992) 824
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 824
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3
  • 5
    • 0024384470 scopus 로고
    • Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
    • Ferrara N., and Henzel W.J. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161 (1989) 851
    • (1989) Biochem Biophys Res Commun , vol.161 , pp. 851
    • Ferrara, N.1    Henzel, W.J.2
  • 6
    • 0024461206 scopus 로고
    • Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis
    • Connolly D.T., Heuvelman D.M., Nelson R., et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 84 (1989) 1470
    • (1989) J Clin Invest , vol.84 , pp. 1470
    • Connolly, D.T.1    Heuvelman, D.M.2    Nelson, R.3
  • 7
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
    • Gerber H.P., and Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 65 (2005) 671
    • (2005) Cancer Res , vol.65 , pp. 671
    • Gerber, H.P.1    Ferrara, N.2
  • 8
    • 33751267529 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor receptor-1 antagonist antibody as a therapeutic agent for cancer
    • Wu Y., Zhong Z., Huber J., et al. Anti-vascular endothelial growth factor receptor-1 antagonist antibody as a therapeutic agent for cancer. Clin Cancer Res 21 (2006) 6573
    • (2006) Clin Cancer Res , vol.21 , pp. 6573
    • Wu, Y.1    Zhong, Z.2    Huber, J.3
  • 9
    • 0344839087 scopus 로고    scopus 로고
    • Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity
    • Zhu Z., Hattori K., Zhang H., et al. Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity. Leukemia 17 (2003) 604
    • (2003) Leukemia , vol.17 , pp. 604
    • Zhu, Z.1    Hattori, K.2    Zhang, H.3
  • 10
    • 16644397669 scopus 로고    scopus 로고
    • Vascular endothelial growth factor as a therapeutic target in cancer
    • Bergsland E.K. Vascular endothelial growth factor as a therapeutic target in cancer. Am J Health Syst Pharm 61 21 Suppl. 5 (2004) S4
    • (2004) Am J Health Syst Pharm , vol.61 , Issue.21 SUPPL. 5
    • Bergsland, E.K.1
  • 11
    • 0031779927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing
    • Nissen N.N., Polverini P.J., Koch A.E., et al. Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol 152 (1998) 1445
    • (1998) Am J Pathol , vol.152 , pp. 1445
    • Nissen, N.N.1    Polverini, P.J.2    Koch, A.E.3
  • 12
    • 0029829884 scopus 로고    scopus 로고
    • Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: Implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis
    • Shifren J.L., Tseng J.F., Zaloudek C.J., et al. Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: Implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis. J Clin Endocrinol Metab 81 (1996) 3112
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3112
    • Shifren, J.L.1    Tseng, J.F.2    Zaloudek, C.J.3
  • 13
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N., and Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 18 (1997) 4
    • (1997) Endocr Rev , vol.18 , pp. 4
    • Ferrara, N.1    Davis-Smyth, T.2
  • 14
    • 85047690366 scopus 로고    scopus 로고
    • Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of antiangiogenic drugs
    • Woltering E.A., Lewis J.M., Maxwell IV P., et al. Development of a novel in vitro human tissue-based angiogenesis assay to evaluate the effect of antiangiogenic drugs. Ann Surg 237 (2003) 790
    • (2003) Ann Surg , vol.237 , pp. 790
    • Woltering, E.A.1    Lewis, J.M.2    Maxwell IV, P.3
  • 15
    • 2142690163 scopus 로고    scopus 로고
    • A new in vitro assay for human tumor angiogenesis: Three-dimensional human tumor angiogenesis assay
    • Gulec S.A., and Woltering E.A. A new in vitro assay for human tumor angiogenesis: Three-dimensional human tumor angiogenesis assay. Ann Surg Oncol 11 (2004) 99
    • (2004) Ann Surg Oncol , vol.11 , pp. 99
    • Gulec, S.A.1    Woltering, E.A.2
  • 16
    • 0024816246 scopus 로고
    • Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells
    • Plouët J., Schilling J., and Gospodarowicz D. Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J 8 (1989) 3801
    • (1989) EMBO J , vol.8 , pp. 3801
    • Plouët, J.1    Schilling, J.2    Gospodarowicz, D.3
  • 17
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger D.R., Galli S.J., Dvorak A.M., et al. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219 (1983) 983
    • (1983) Science , vol.219 , pp. 983
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3
  • 18
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D.W., Cachianes G., Kuang W.J., et al. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246 (1989) 1306
    • (1989) Science , vol.246 , pp. 1306
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3
  • 19
    • 0028670958 scopus 로고
    • Vascular endothelial growth factor (rhVEGF165) stimulates direct angiogenesis in the rabbit cornea
    • Phillips G.D., Stone A.M., Jones B.D., et al. Vascular endothelial growth factor (rhVEGF165) stimulates direct angiogenesis in the rabbit cornea. In vivo 8 (1994) 961
    • (1994) In vivo , vol.8 , pp. 961
    • Phillips, G.D.1    Stone, A.M.2    Jones, B.D.3
  • 20
    • 0033964460 scopus 로고    scopus 로고
    • Platelet-activating factor enhances vascular endothelial growth factor-induced endothelial cell motility and neoangiogenesis in a murine matrigel model
    • Montrucchio G., Lupia E., Battaglia E., et al. Platelet-activating factor enhances vascular endothelial growth factor-induced endothelial cell motility and neoangiogenesis in a murine matrigel model. Arterioscler Thromb Vasc Biol 20 (2000) 80
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 80
    • Montrucchio, G.1    Lupia, E.2    Battaglia, E.3
  • 21
    • 0028344109 scopus 로고
    • Therapeutic angiogenesis. A single intra-arterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model
    • Takeshita S., Zheng L.P., Brogi E., et al. Therapeutic angiogenesis. A single intra-arterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest 93 (1994) 662
    • (1994) J Clin Invest , vol.93 , pp. 662
    • Takeshita, S.1    Zheng, L.P.2    Brogi, E.3
  • 22
    • 0029739620 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is sufficient to produce iris neovascularization and neovascular glaucoma in a nonhuman primate
    • Tolentino M.J., Miller J.W., Gragoudas E.S., et al. Vascular endothelial growth factor is sufficient to produce iris neovascularization and neovascular glaucoma in a nonhuman primate. Arch Ophthalmol 114 (1996) 964
    • (1996) Arch Ophthalmol , vol.114 , pp. 964
    • Tolentino, M.J.1    Miller, J.W.2    Gragoudas, E.S.3
  • 23
    • 9344236065 scopus 로고    scopus 로고
    • Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients
    • Yamamoto Y., Toi M., Kondo S., et al. Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients. Clin Cancer Res 2 (1996) 821
    • (1996) Clin Cancer Res , vol.2 , pp. 821
    • Yamamoto, Y.1    Toi, M.2    Kondo, S.3
  • 24
    • 0037453099 scopus 로고    scopus 로고
    • The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis
    • Henry T.D., Annex B.H., McKendall G.R., et al. The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation 107 (2003) 1359
    • (2003) Circulation , vol.107 , pp. 1359
    • Henry, T.D.1    Annex, B.H.2    McKendall, G.R.3
  • 25
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H., Fehrenbacher L., Novotny W., et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350 (2004) 2335
    • (2004) N Engl J Med , vol.350 , pp. 2335
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 26
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • Jain R.K. Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy. Nat Med 7 (2001) 987
    • (2001) Nat Med , vol.7 , pp. 987
    • Jain, R.K.1
  • 27
    • 33751108557 scopus 로고    scopus 로고
    • Metabolism and disposition of vatalanib (PTK787/ZK-222584) in cancer patients
    • Jost L.M., Gschwind H.P., Jalava T., et al. Metabolism and disposition of vatalanib (PTK787/ZK-222584) in cancer patients. Drug Metab Dispos 34 (2006) 1817
    • (2006) Drug Metab Dispos , vol.34 , pp. 1817
    • Jost, L.M.1    Gschwind, H.P.2    Jalava, T.3
  • 28
    • 0034655182 scopus 로고    scopus 로고
    • PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
    • Wood J.M., Bold G., Buchdunger E., et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 60 (2000) 2178
    • (2000) Cancer Res , vol.60 , pp. 2178
    • Wood, J.M.1    Bold, G.2    Buchdunger, E.3
  • 29
    • 33749637207 scopus 로고    scopus 로고
    • Results of an interim analysis of a multinational randomized, double-blind, phase III study in patients (pts) with previously treated metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK787/ZK 222584 (PTK/ZK) or placebo (CONFIRM 2)
    • abstract 3509
    • Koehne E., Bajetta E., Lin E., et al. Results of an interim analysis of a multinational randomized, double-blind, phase III study in patients (pts) with previously treated metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK787/ZK 222584 (PTK/ZK) or placebo (CONFIRM 2). J Clin Oncol 24 (2006) 18S abstract 3509
    • (2006) J Clin Oncol , vol.24
    • Koehne, E.1    Bajetta, E.2    Lin, E.3
  • 30
    • 0032962265 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor
    • Lin Y.S., Mguyen C., Mendoza J.L., et al. Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor. J Pharmacol Exp Ther 288 (1999) 371
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 371
    • Lin, Y.S.1    Mguyen, C.2    Mendoza, J.L.3
  • 31
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon M.S., Margolin K., Talpaz M., et al. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 19 (2001) 843
    • (2001) J Clin Oncol , vol.19 , pp. 843
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3
  • 32
    • 0037386937 scopus 로고    scopus 로고
    • A phase I study of anti-kinase insert domain-containing receptor antibody, IMC-1C11, in patients with liver metastases from colorectal carcinoma
    • Posey J.A., Ng T.C., Yang B., et al. A phase I study of anti-kinase insert domain-containing receptor antibody, IMC-1C11, in patients with liver metastases from colorectal carcinoma. Clin Cancer Res 9 (2003) 1323
    • (2003) Clin Cancer Res , vol.9 , pp. 1323
    • Posey, J.A.1    Ng, T.C.2    Yang, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.