Apoptotic-related protein changes induced by hexavalent chromium in mice liver

Environmental Toxicology

Volumn 25, Issue 1, 2010, Pages 77-82

  Wang, Xiao Feng ^a,b   Lou, Xiao Ming ^a   Shen, Ying ^c   Xing, Ming Luan ^a   Xu, Li Hong ^b  

^a ZHEJIANG PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Bax; Bcl 2; Caspase 3; Cr(VI); Cytochrome c; In vivo; p53

Indexed keywords

APOPTOSIS; APOPTOTIC; BODY WEIGHT; CASPASE-3; CELL TYPES; CYTOCHROME C; EXPRESSION LEVELS; HEXAVALENT CHROMIUM; IN-VIVO; INDUCED APOPTOSIS; MICE LIVER; MOLECULAR MECHANISM; POTASSIUM DICHROMATES; PROTEIN EXPRESSIONS;

CELL DEATH; CHROMIUM COMPOUNDS; GENE EXPRESSION; LIVER; POTASSIUM; PROTEINS;

CHROMIUM;

APOPTOSIS REGULATORY PROTEIN; CASPASE 3; CHROMIUM; CYTOCHROME C; DICHROMATE POTASSIUM; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; BIOACCUMULATION; BIOCHEMISTRY; CHROMIUM; CYTOCHROME; CYTOLOGY; PROTEIN; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME REGULATION; LIVER CELL; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; DNA DAMAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LETHAL DOSE 50; LIVER; MALE; MICE; POTASSIUM DICHROMATE;

MUS;

EID: 76749117135     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20478     Document Type: Article

References (28)

1. Brady HJ, Gil-Gomez G. 1998. Bax. The pro-apoptotic Bcl-2 family member, Bax. Int J Biochem Cell Biol 30:647-650.
2. Bredesen DE. 2000. Apoptosis: Overview and signal transduction pathways. J Neurotrauma 17:801-810.
3. Cahill J, Nixon R. 2004. Localized recurrence of chromate dermatitis. Contact Dermatitis 51:214.
4. Carlisle DL, Pritchard DE, Singh J, Patierno SR. 2000. Chromium( VI) induces p53-dependent apoptosis in diploid human lung and mouse dermal fibroblasts. Mol Carcinog 28:111-118.
5. Cohen GM. 1997. Caspases: The executioners of apoptosis. Biochem J 326 (Part 1):1-16.
6. D'Agostini F, Izzotti A, Bennicelli C, Camoirano A, Tampa E, De Flora S. 2002. Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI). Carcinogenesis 23:587-593.
7. Fridman JS, Lowe SW. 2003. Control of apoptosis by p53. Oncogene 22:9030-9040.
8. Hayashi Y, Kondo T, Zhao QL, Ogawa R, Cui ZG, Feril LB, Jr, Teranishi H, Kasuya M. 2004. Signal transduction of p53-independent apoptotic pathway induced by hexavalent chromium in U937 cells. Toxicol Appl Pharmacol 197:96-106.
9. Kwan KH, Chan HM, de Lafontaine Y. 2003. Metal contamination in zebra mussels (Dreissena polymorpha) along the St. Lawrence River. Environ Monit Assess 88:193-219.
10. Lanca S, Alves A, Vieira AI, Barata J, de Freitas J, de Carvalho A. 2002. Chromium-induced toxic hepatitis. Eur J Intern Med 13:518-520.
11. Loeffler M, Kroemer G. 2000. The mitochondrion in cell death control: Certainties and incognita. Exp Cell Res 256:19-26.
12. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
13. Maine MA, Sune NL, Lagger SC. 2004. Chromium bioaccumulation: Comparison of the capacity of two floating aquatic macrophytes. Water Res 38:1494-1501.
14. Naqvi SM, Rizvi SA. 2000. Accumulation of chromium and copper in three different soils and bioaccumulation in an aquatic plant, Alternanthera philoxeroides. Bull Environ Contam Toxicol 65:55-61.
15. O'Brien TJ, Ceryak S, Patierno SR. 2003. Complexities of chromium carcinogenesis: Role of cellular response, repair and recovery mechanisms. Mutat Res 533:3-36.
16. Pandey V, Dixit V, Shyam R. 2005. Antioxidative responses in relation to growth of mustard (Brassica juncea cv. Pusa Jaikisan) plants exposed to hexavalent chromium. Chemosphere 61:40-47.
17. Perlman H, Zhang X, Chen MW, Walsh K, Buttyan R. 1999. An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis. Cell Death Differ 6:48-54.
18. Philchenkov A. 2004. Caspases: Potential targets for regulating cell death. J Cell Mol Med 8:432-444.
19. Pritchard DE, Singh J, Carlisle DL, Patierno SR. 2000. Cyclosporin A inhibits chromium(VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells. Carcinogenesis 21:2027-2033.
20. Rowbotham AL, Levy LS, Shuker LK. 2000. Chromium in the environment: An evaluation of exposure of the UK general population and possible adverse health effects. J Toxicol Environ Health B Crit Rev 3:145-178.
21. Rudolf E, Cervinka M, Cerman J, Schroterova L. 2005. Hexavalent chromium disrupts the actin cytoskeleton and induces mitochondria-dependent apoptosis in human dermal fibroblasts. Toxicol In Vitro 19:713-723.
22. Russo P, Catassi A, Cesario A, Imperatori A, Rotolo N, Fini M, Granone P, Dominioni L. 2005. Molecular mechanisms of hexavalent chromium-induced apoptosis in human bronchoalveolar cells. Am J Respir Cell Mol Biol 33:589-600.
23. Sinha S, Saxena R, Singh S. 2005. Chromium induced lipid peroxidation in the plants of Pistia stratiotes L.: Role of antioxidants and antioxidant enzymes. Chemosphere 58:595-604.
24. Tsujimoto Y. 2003. Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol 195:158-167.
25. Wang S, Shi X. 2001. Mechanisms of Cr(VI)-induced p53 activation: The role of phosphorylation, mdm2 and ERK. Carcinogenesis 22:757-762.
26. Wang XF, Xing ML, Shen Y, Zhu X, Xu LH. 2006. Oral administration of Cr(VI) induced oxidative stress. DNA damage and apoptotic cell death in mice. Toxicology 228:16-23.
27. Yu J, Zhang L. 2005. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 331:851-858.
28. Zhitkovich A. 2005. Importance of chromium-DNA adducts in mutagenicity and toxicity of chromium(VI). Chem Res Toxicol 18:3-11.