Congenital heart disease in pregnancies complicated by maternal diabetes mellitus: An international clinical collaboration, literature review, and meta-analysis

Herz

Volumn 35, Issue 1, 2010, Pages 19-26

  Lisowski, Lukas A ^a   Verheijen, Paul M ^b   Copel, Joshua A ^c   Kleinman, Charles S ^d   Wassink, Sander ^e   Visser, Gerard H A ^f   Meijboom, Erik Jan ^g  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b DEPARTMENT OF SURGERY   (Netherlands)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e Infection and Immunology   (Netherlands)

^f UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^g LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Congenital heart disease; Congenital structural cardiac malformations; Periconceptional glycemic control

Indexed keywords

HEMOGLOBIN A1C;

ADULT; AORTA ARCH ANOMALY; AORTA COARCTATION; ARTICLE; ATRIOVENTRICULAR SEPTAL DEFECT; CLINICAL ARTICLE; CLINICAL STUDY; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DISEASE REGISTRY; EBSTEIN ANOMALY; FEMALE; FETUS; FIRST TRIMESTER PREGNANCY; GLYCEMIC CONTROL; GREAT VESSELS TRANSPOSITION; HEART ATRIUM SEPTUM DEFECT; HEART RIGHT VENTRICLE DOUBLE OUTLET; HEART SINGLE VENTRICLE; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HYPOPLASTIC LEFT HEART SYNDROME; INCIDENCE; INFORMATION RETRIEVAL; INSULIN DEPENDENT DIABETES MELLITUS; MATERNAL DIABETES MELLITUS; MEDICAL RECORD REVIEW; NETHERLANDS; PARTIAL ANOMALOUS PULMONARY VENOUS CONNECTION; PATENT DUCTUS ARTERIOSUS; POPULATION; PROGENY; PULMONARY ARTERY MALFORMATION; RETROSPECTIVE STUDY; TRICUSPID VALVE DISEASE; VISCERAL HETEROATAXIA;

CROSS-CULTURAL COMPARISON; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 1; DISEASES IN TWINS; EUROPE; FEMALE; HEART DEFECTS, CONGENITAL; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIC AGENTS; INCIDENCE; INFANT, NEWBORN; INSULIN; NETHERLANDS; PREGNANCY; PREGNANCY IN DIABETICS; PREGNANCY, MULTIPLE; REFERENCE VALUES; RETROSPECTIVE STUDIES; RISK; RISK FACTORS; ULTRASONOGRAPHY, PRENATAL; UNITED STATES;

EID: 76749105214     PISSN: 03409937     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00059-010-3244-3     Document Type: Article

References (64)

1. 1c values in early pregnancy Br Med J 289 345 6 10.1136/bmj.289.6441.345 1:STN:280: DyaL2c3otFGluw%3D%3D
2. L. Molsted-Pedersen I. Tygstrup J. Pedersen 1964 Congenital malformations in newborn infants of diabetic women Lancet 1 1124 6 10.1016/S0140-6736(64) 91805-7
3. J. Kucera 1971 Rate and type of congenital anomalies among offspring of diabetic women J Reprod Med 7 73 82 1:STN:280:DyaE38%2Fgs1emsg%3D%3D 5095696
4. M. Miodovnik F. Mimouni P.S. Dignan 1988 Major malformations in infants of IDDM women. Vasculopathy and early first-trimester poor glycemic control Diabetes Care 11 713 8 10.2337/diacare.11.9.713 1:STN:280:DyaL1M7js1Ohsw%3D%3D 3224542
5. I.F. Casson C.A. Clarke C.V. Howard 1997 Outcomes of pregnancy in insulin dependent diabetic women: results of a five year population cohort study Br Med J 315 275 8 1:STN:280:DyaK2svitVSguw%3D%3D
6. J.L. Kitzmiller J.P. Cloherty M.D. Younger 1978 Diabetic pregnancy and perinatal morbidity Am J Obstet Gynecol 131 560 80 1:STN:280: DyaE1c3jt1Oksw%3D%3D 354386
7. S.G. Gabbe 1977 Congenital malformations in infants of diabetic mothers Obstet Gynecol Surv 32 125 32 10.1097/00006254-197703000-00001 1:STN:280:DyaE2s7ntF2nsA%3D%3D 857205
8. J. Pedersen L.M. Molsted-Pedersen 1978 Congenital malformations: the possible role of diabetes care outside pregnancy Ciba Found Symp 63 265 71 256545
9. B.A. Meyer S.M. Palmer 1990 Pregestational diabetes Semin Perinatol 14 12 23 1:STN:280:DyaK3c7ptlOhtQ%3D%3D 2180071
10. K. Fuhrmann H. Reiher K. Semmler 1983 Prevention of congenital malformations in infants of insulin-dependent diabetic mothers Diabetes Care 6 219 23 10.2337/diacare.6.3.219 1:STN:280:DyaL3s3mtFWntg%3D%3D 6347574
11. B. Rosenn M. Miodovnik C.A. Combs 1994 Glycemic thresholds for spontaneous abortion and congenital malformations in insulin-dependent diabetes mellitus Obstet Gynecol 84 515 20 1:STN:280:DyaK2cznslSksw%3D%3D 8090386
12. C. Lowy R.W. Beard J. Goldschmidt 1986 The UK diabetic pregnancy survey Acta Endocrinol Suppl (Copenh) 277 86 9 1:STN:280:DyaL2s%2FitF2isQ%3D%3D
13. J.E. Becerra M.J. Khoury J.F. Cordero J.D. Erickson 1990 Diabetes mellitus during pregnancy and the risks for specific birth defects: a population-based case-control study Pediatrics 85 1 9 1:STN:280: DyaK3c7hsFWluw%3D%3D 2404255
14. J.L. Kitzmiller L.A. Gavin G.D. Gin 1991 Preconception care of diabetes. Glycemic control prevents congenital anomalies JAMA 265 731 6 10.1001/jama.265.6.731 1:STN:280:DyaK3M7hs1Kqsg%3D%3D 1990188
15. J.L. Mills L. Baker A.S. Goldman 1979 Malformations in infants of diabetic mothers occur before the seventh gestational week. Implications for treatment Diabetes 28 292 3 10.2337/diabetes.28.4.292 1:STN:280: DyaE1M7ntVCnsg%3D%3D 437367
16. P.M. Verheijen L.A. Lisowski P. Stoutenbeek 2001 Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient J Thorac Cardiovasc Surg 121 798 803 10.1067/mtc.2001.112825 1:STN:280: DC%2BD3M3itFSgtg%3D%3D 11279423
17. J.L. Mills R.H. Knopp J.L. Simpson 1988 Lack of relation of increased malformation rates in infants of diabetic mothers to glycemic control during organogenesis N Engl J Med 318 671 6 1:STN:280:DyaL1c7ktlShtA%3D%3D 3344018
18. G. Gladman B.W. McCrindle C. Boutin J.F. Smallhorn 1997 Fetal echocardiographic screening of diabetic pregnancies for congenital heart disease Am J Perinatol 14 59 62 10.1055/s-2007-994098 1:STN:280:DyaK2svgs1Cmsw%3D%3D 9259899
19. 1c in predicting fetal heart disease in diabetic pregnancies Obstet Gynecol 159 352 6
20. T.W. Rowland J.P. Hubbell A.S. Nadas 1973 Congenital heart disease in infants of diabetic mothers J Pediatr 83 815 20 10.1016/S0022-3476(73)80374-9 1:STN:280:DyaE2c%2FgsFWhug%3D%3D 4742573
21. M.A. Ramos-Arroyo E. Rodriguez-Pinilla J.F. Cordero 1992 Maternal diabetes: the risk for specific birth defects Eur J Epidemiol 8 503 8 10.1007/BF00146367 1:STN:280:DyaK3s%2FhtFymsw%3D%3D 1397216
22. C. Ferencz J.D. Rubin R.J. McCarter E.B. Clark 1990 Maternal diabetes and cardiovascular malformations: predominance of double outlet right ventricle and truncus arteriosus Teratology 41 319 26 10.1002/tera.1420410309 1:STN:280:DyaK3c3itlehsw%3D%3D 2326756
23. Z.A. Brown J.L. Mills B.E. Metzger 1992 Early sonographic evaluation for fetal growth delay and congenital malformations in pregnancies complicated by insulin-requiring diabetes. National Institute of Child Health and Human Development Diabetes in Early Pregnancy Study Diabetes Care 15 613 9 10.2337/diacare.15.5.613 1:STN:280:DyaK38zoslSntA%3D%3D 1516479
24. 1 and risk for major malformation and spontaneous abortion in diabetic pregnancy Teratology 39 225 31 10.1002/tera.1420390303 1:STN:280:DyaL1M3mslGmsw%3D%3D 2727930 (Pubitemid 19108914)
25. L. Suhonen V. Hiilesmaa K. Teramo 2000 Glycaemic control during early pregnancy and fetal malformations in women with type I diabetes mellitus Diabetologia 43 79 82 10.1007/s001250050010 1:STN:280:DC%2BD3c7js1erug%3D%3D 10663219
26. 1 and congenital malformation Diabet Med 4 156 9 10.1111/j.1464-5491.1987.tb00853.x 1:STN:280:DyaL2s7ovVOguw%3D%3D 2952434
27. J.F. Pedersen L. Molsted-Pedersen 1981 Early fetal growth delay detected by ultrasound marks increased risk of congenital malformation in diabetic pregnancy Br Med J (Clin Res Ed) 283 269 71 10.1136/bmj.283.6286.269 1:STN:280:DyaL3M3jtlyhtw%3D%3D
28. M. Small L. Cassidy J.M. Leiper 1986 Outcome of pregnancy in insulin-dependent (type 1) diabetic women between 1971 and 1984 Q J Med 61 1159 61 1:STN:280:DyaL1c%2Fhs1yhsA%3D%3D 3310067
29. M.J. Khoury J.E. Becerra J.F. Cordero J.D. Erickson 1989 Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy Pediatrics 84 658 65 1:STN:280:DyaL1MzosFOmsA%3D%3D 2674881
30. K.F. McFarland E. Hemaya 1985 Neonatal mortality in infants of diabetic mothers Diabetes Care 8 333 6 10.2337/diacare.8.4.333 1:STN:280: DyaL28%2FgsVSitA%3D%3D 4042799
31. F. Mimouni M. Miodovnik R.C. Tsang 1987 Decreased maternal serum magnesium concentration and adverse fetal outcome in insulin-dependent diabetic women Obstet Gynecol 70 85 8 1:STN:280:DyaL2s3lvFaktA%3D%3D 3601271
32. J.L. Ballard J. Holroyde R.C. Tsang 1984 High malformation rates and decreased mortality in infants of diabetic mothers managed after the first trimester of pregnancy (1956-1978) Am J Obstet Gynecol 148 1111 8 1:STN:280:DyaL2c7ns1WrsA%3D%3D 6711647
33. L. Cordero S.H. Treuer M.B. Landon S.G. Gabbe 1998 Management of infants of diabetic mothers Arch Pediatr Adolesc Med 152 249 54 1:STN:280: DyaK1c7ptVamuw%3D%3D 9529462
34. T.J. Albert M.B. Landon J.J. Wheller 1996 Prenatal detection of fetal anomalies in pregnancies complicated by insulin-dependent diabetes mellitus Am J Obstet Gynecol 174 1424 8 10.1016/S0002-9378(96)70583-5 1:STN:280: DyaK283ktVSlug%3D%3D 9065106 (Pubitemid 26165255)
35. A. Aberg L. Westbom B. Kallen 2001 Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes Early Hum Dev 61 85 95 10.1016/S0378-3782(00)00125-0 1:STN:280:DC%2BD3M7ps1Cgtg%3D%3D 11223271 (Pubitemid 32149652)
36. Centers for Disease Control. 1989 Contribution of birth defects to infants' mortality - United States 1986 MMWR 38 633 5
37. Weatherall DJ, Ledingham JGG, Warrell DA. Oxford textbook of medicine, vol 1, 2nd edn. Oxford: Oxford University Press, 1987:985-6.
38. G. Hawthorne S. Robson E.A. Ryall 1997 Prospective population based survey of outcome of pregnancy in diabetic women: results of the Northern Diabetic Pregnancy Audit, 1994 BMJ 315 279 81 1:STN:280:DyaK2svitVSnsg%3D%3D 9274546
39. I.M. Evers A.M. Bos A.L. Aalders 2000 Zwangerschap bij vrouwen met diabetes mellitus type-1: nog steeds maternale en perinatale complicaties, ondanks goede bloedglucoseregulatie Ned Tijdschr Geneeskd 144 804 9 1:STN:280:DC%2BD3c3mtVentw%3D%3D 10800551
40. I.M. Evers H.W. de Valk G.H.A. Visser 2001 A nationwide prospective study on the outcome of pregnancies in women with type 1 diabetes mellitus: do planned pregnancies result in better pregnancy outcome? Diabetologia 44 1 A42
41. D. Hurwitz I.C. Irving 1937 Diabetes and pregnancy Am J Med Sci 194 85 92 10.1097/00000441-193707000-00011
42. H.C. Miller 1946 Mortality in pregnancies complicated by diabetes JAMA 131 700
43. C.A. Loffredo P.D. Wilson C. Ferencz 2001 Maternal diabetes: an independent risk factor for major cardiovascular malformations with increased mortality of affected infants Teratology 44 98 106 10.1002/tera.1051 (Pubitemid 32702475)
44. Larsen WJ. Human embryology. New York: Churchill Livingstone, 1993:161-3.
45. H. Yasui M. Morishima M. Nakazawa 1999 Developmental spectrum of cardiac outflow tract anomalies encompassing transposition of the great arteries and dextroposition of the aorta: pathogenic effect of extrinsic retinoic acid in the mouse embryo Anat Rec 254 253 60 10.1002/(SICI)1097-0185(19990201)254:2<253: :AID-AR11>3.0.CO;2-4 1:CAS:528:DyaK1MXht1emurk%3D 9972810 (Pubitemid 29053229)
46. C.M. Siman G. A. Gittenberger-De B. Wisse U.J. Eriksson 2000 Malformations in offspring of diabetic rats: morphometric analysis of neural crest-derived organs and effects of maternal vitamin E treatment Teratology 61 355 67 10.1002/(SICI)1096-9926(200005)61:5<355::AID-TERA7>3.0.CO;2-W 1:CAS:528:DC%2BD3cXivFKqurY%3D 10777831 (Pubitemid 30258821)
47. E. Goldmuntz B.J. Clark L.E. Mitchell 1998 Frequency of 22q11 deletions in patients with conotruncal defects J Am Coll Cardiol 32 492 8 10.1016/S0735-1097(98)00259-9 1:STN:280:DyaK1cznt1WrtA%3D%3D 9708481 (Pubitemid 28396502)
48. E. Goldmuntz R. Bamford J.D. Karkera 2002 CFC1 mutations in patients with transposition of the great arteries and double-outlet right ventricle Am J Hum Genet 70 776 80 10.1086/339079 1:CAS:528:DC%2BD38XislChtrc%3D 11799476 (Pubitemid 34177932)
49. T.A. Wilson S.L. Blethen A. Vallone 1993 DiGeorge anomaly with renal agenesis in infants of mothers with diabetes Am J Med Genet 47 1078 82 10.1002/ajmg.1320470729 1:STN:280:DyaK2c7itFSlsA%3D%3D 8291527 (Pubitemid 23323415)
50. I.S. Kathiriya D. Srivastava 2000 Left-right asymmetry and cardiac looping: implications for cardiac development and congenital heart disease Am J Med Genet 97 271 9 10.1002/1096-8628(200024)97:4<271::AID-AJMG1277>3.0. CO;2-O 1:STN:280:DC%2BD3M3ps1Ciuw%3D%3D 11376438 (Pubitemid 32463491)
51. D. Srivastava 2001 Genetic assembly of the heart: implications for congenital heart disease Annu Rev Physiol 63 451 69 10.1146/annurev.physiol.63. 1.451 1:CAS:528:DC%2BD3MXjtFKmtb8%3D 11181963 (Pubitemid 32304325)
52. A. Slavotinek E. Hellen S. Gould 1996 Three infants of diabetic mothers with malformations of left-right asymmetry - further evidence for the aetiological role of diabetes in this malformation spectrum Clin Dysmorphol 5 241 7 10.1097/00019605-199607000-00008 1:STN:280:DyaK28vhsFGhug%3D%3D 8818453
53. M. Splitt C. Wright D. Sen J. Goodship 1999 Left-isomerism sequence and maternal type-1 diabetes Lancet 354 305 6 10.1016/S0140-6736(99)01942-X 1:STN:280:DyaK1Mzms12htA%3D%3D 10440314 (Pubitemid 29348746)
54. M.L. Martinez-Frias 2001 Heterotaxia as an outcome of maternal diabetes: an epidemiological study Am J Med Genet 99 142 6 10.1002/1096-8628(2000)9999: 999<00::AID-AJMG1139>3.0.CO;2-Z 1:STN:280:DC%2BD3Mzit1ykuw%3D%3D 11241474 (Pubitemid 32204786)
55. H. Kalter 1993 Case reports of malformations associated with maternal diabetes: history and critique Clin Genet 43 174 9 1:STN:280: DyaK3szitFCiug%3D%3D 8330451
56. M.P. Goto A.S. Goldman 1994 Diabetic embryopathy Curr Opin Pediatr 6 486 91 10.1097/00008480-199408000-00023 1:STN:280:DyaK2M%2FjvFalsg%3D%3D 7951674
57. R.J. McCarter I.I. Kessler G.W. Comstock 1987 Is diabetes mellitus a teratogen or a coteratogen? Am J Epidemiol 125 195 205 1:STN:280: DyaL2s7isVOntQ%3D%3D 3812428
58. E.A. Reece C.J. Homko Y.K. Wu 1996 Multifactorial basis of the syndrome of diabetic embryopathy Teratology 54 171 82 10.1002/(SICI)1096-9926(199610)54: 4<171::AID-TERA1>3.0.CO;2-4 1:CAS:528:DyaK2sXhsVaqsLw%3D 9122886 (Pubitemid 27087007)
59. 1c in early pregnancy and major congenital anomalies in infants of diabetic mothers N Engl J Med 304 1331 4 1:STN:280:DyaL3M7nt12itA%3D%3D 7012627
60. J. Cederberg C.M. Siman U.J. Eriksson 2001 Combined treatment with vitamin E and vitamin C decreases oxidative stress and improves fetal outcome in experimental diabetic pregnancy Pediatr Res 49 755 62 10.1203/00006450- 200106000-00007 1:CAS:528:DC%2BD3MXltVOitLk%3D 11385134
61. P.M. Verheijen L.A. Lisowski P. Stoutenbeek 2002 Lactacidosis in the neonate is minimized by prenatal detection of congenital heart disease Ultrasound Obstet Gynecol 19 552 5 10.1046/j.1469-0705.2002.00714.x 1:STN:280:DC%2BD38zgs1Gruw%3D%3D 12047532 (Pubitemid 34626116)
62. D. Bonnet A. Coltri G. Butera 1999 Detection of transposition of the great arteries in fetuses reduces neonatal morbidity and mortality Circulation 99 916 8 1:STN:280:DyaK1M7lt1SktQ%3D%3D 10027815
63. W. Tworetzky D.B. McElhinney V.M. Reddy 2001 Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome Circulation 103 1269 73 1:STN:280:DC%2BD3M3msFCqtw%3D%3D 11238272
64. O. Franklin M. Burch N. Manning 2002 Prenatal diagnosis of coarctation of the aorta improves survival and reduces morbidity Heart 87 67 9 10.1136/heart.87.1.67 1:STN:280:DC%2BD38%2FgtlWjuw%3D%3D 11751670